Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   B7R57_RS11610 Genome accession   NZ_CP020656
Coordinates   2248568..2249284 (-) Length   238 a.a.
NCBI ID   WP_000688498.1    Uniprot ID   Q2VG52
Organism   Staphylococcus aureus strain K5     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2243568..2254284
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  B7R57_RS11590 (B7R57_11610) - 2244652..2245602 (+) 951 WP_101766724.1 LacI family DNA-binding transcriptional regulator -
  B7R57_RS11595 (B7R57_11615) - 2245751..2247235 (+) 1485 WP_000141414.1 sucrose-6-phosphate hydrolase -
  B7R57_RS11600 (B7R57_11620) - 2247232..2248191 (+) 960 WP_001253314.1 carbohydrate kinase -
  B7R57_RS11605 (B7R57_11625) - 2248379..2248488 (-) 110 Protein_2216 hypothetical protein -
  B7R57_RS11610 (B7R57_11630) agrA 2248568..2249284 (-) 717 WP_000688498.1 quorum-sensing response regulator AgrA Regulator
  B7R57_RS11615 (B7R57_11635) agrC 2249303..2250586 (-) 1284 WP_000447888.1 quorum-sensing sensor histidine kinase AgrC -
  B7R57_RS11620 (B7R57_11640) agrD 2250616..2250759 (-) 144 WP_001094921.1 cyclic lactone autoinducer peptide AgrD -
  B7R57_RS11625 (B7R57_11645) - 2250762..2251325 (-) 564 WP_001105696.1 accessory gene regulator AgrB -
  B7R57_RS14480 (B7R57_11650) - 2251561..2251695 (+) 135 WP_001549197.1 delta-lysin family phenol-soluble modulin -
  B7R57_RS11635 (B7R57_11655) - 2252292..2253077 (-) 786 WP_101766725.1 carbon-nitrogen family hydrolase -
  B7R57_RS11640 (B7R57_11665) - 2253438..2254063 (-) 626 Protein_2223 nitroreductase family protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27933.91 Da        Isoelectric Point: 6.0927

>NTDB_id=225298 B7R57_RS11610 WP_000688498.1 2248568..2249284(-) (agrA) [Staphylococcus aureus strain K5]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSRDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=225298 B7R57_RS11610 WP_000688498.1 2248568..2249284(-) (agrA) [Staphylococcus aureus strain K5]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGCTTACAATTAT
TATCAAGAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTTAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-237)

Response regulator receiver domain (Response_reg)

(3-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q2VG52

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

99.58

100

0.996

Multiple sequence alignment