Detailed information NTG0225092

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: B7H15_RS14615
• Genome accession: NZ_CP020619
• Coordinates: 2770156..2771043 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain JE2
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2765156..2776043

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
B7H15_RS14580 (B7H15_14580)	-	2765175..2765267 (+)	93	WP_010956583.1	hypothetical protein	-
B7H15_RS14585 (B7H15_14585)	-	2765375..2765872 (-)	498	WP_001065268.1	glutathione peroxidase	-
B7H15_RS14590 (B7H15_14590)	-	2765882..2766142 (-)	261	WP_001789910.1	hypothetical protein	-
B7H15_RS14600 (B7H15_14600)	-	2766524..2766637 (-)	114	WP_001791776.1	hypothetical protein	-
B7H15_RS14605 (B7H15_14605)	-	2767296..2769296 (-)	2001	WP_000776751.1	ABC transporter permease	-
B7H15_RS14610 (B7H15_14610)	-	2769293..2770048 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
B7H15_RS14615 (B7H15_14615)	braS	2770156..2771043 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
B7H15_RS14620 (B7H15_14620)	braR	2771054..2771719 (-)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
B7H15_RS14625 (B7H15_14625)	-	2771745..2771945 (-)	201	WP_000604728.1	hypothetical protein	-
B7H15_RS14630 (B7H15_14630)	-	2772143..2773567 (+)	1425	WP_000953744.1	alkaline phosphatase	-
B7H15_RS15630 (B7H15_14635)	-	2773627..2773728 (-)	102	WP_000731972.1	SE2200 family small protein	-
B7H15_RS14640 (B7H15_14640)	-	2773850..2774305 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
B7H15_RS14645 (B7H15_14645)	-	2774550..2775311 (-)	762	WP_000323455.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=225092 B7H15_RS14615 WP_000143419.1 2770156..2771043(-) (braS) [Staphylococcus aureus strain JE2]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=225092 B7H15_RS14615 WP_000143419.1 2770156..2771043(-) (braS) [Staphylococcus aureus strain JE2]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997