Detailed information NTG0224040

Bioinformatically predicted

Overview

• Name: irvR
• Type: Regulator
• Locus tag: RL05_RS03420
• Genome accession: NZ_CP026074
• Coordinates: 572059..572766 (+)
• Length: 235 a.a.
• NCBI ID: WP_000094093.1
• Uniprot ID: A0A1D4DWM6
• Organism: Staphylococcus aureus strain FDAARGOS_47
• Function: regulate expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 567059..577766

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
RL05_RS03365 (RL05_003365)	-	567954..568217 (-)	264	WP_001205732.1	hypothetical protein	-
RL05_RS03370 (RL05_003370)	-	568226..568486 (-)	261	WP_000291506.1	DUF1108 family protein	-
RL05_RS03375 (RL05_003375)	-	568491..568794 (-)	304	Protein_622	DUF2482 family protein	-
RL05_RS03380 (RL05_003380)	-	568888..569049 (-)	162	WP_031766022.1	DUF1270 domain-containing protein	-
RL05_RS03385 (RL05_003385)	-	569046..569366 (-)	321	WP_001120197.1	DUF771 domain-containing protein	-
RL05_RS03390 (RL05_003390)	-	569421..569801 (+)	381	WP_000762521.1	DUF2513 domain-containing protein	-
RL05_RS03395 (RL05_003395)	-	569788..569985 (-)	198	WP_001148862.1	hypothetical protein	-
RL05_RS03400 (RL05_003400)	-	570001..570756 (-)	756	WP_001148343.1	phage antirepressor KilAC domain-containing protein	-
RL05_RS03405 (RL05_003405)	-	570813..571352 (+)	540	WP_000351243.1	hypothetical protein	-
RL05_RS03410 (RL05_003410)	-	571376..571636 (-)	261	WP_000435341.1	transcriptional regulator	-
RL05_RS03415 (RL05_003415)	-	571649..571888 (-)	240	WP_000548576.1	helix-turn-helix transcriptional regulator	-
RL05_RS03420 (RL05_003420)	irvR	572059..572766 (+)	708	WP_000094093.1	XRE family transcriptional regulator	Regulator
RL05_RS15380	-	572778..572924 (+)	147	WP_001049401.1	hypothetical protein	-
RL05_RS03425 (RL05_003425)	-	572921..573106 (+)	186	WP_000100503.1	hypothetical protein	-
RL05_RS03430 (RL05_003430)	-	573306..573473 (+)	168	WP_031806878.1	hypothetical protein	-
RL05_RS03435 (RL05_003435)	-	573771..574844 (+)	1074	WP_031929590.1	Abi family protein	-
RL05_RS03440 (RL05_003440)	-	574905..575942 (+)	1038	WP_000857188.1	site-specific integrase	-
RL05_RS03445 (RL05_003445)	sph	575993..576823 (+)	831	Protein_637	sphingomyelin phosphodiesterase	-

Sequence

Protein

• Length: 235 a.a.
• Molecular weight: 26769.35 Da
• Isoelectric Point: 5.4082

>NTDB_id=224040 RL05_RS03420 WP_000094093.1 572059..572766(+) (irvR) [Staphylococcus aureus strain FDAARGOS_47]
MSSFSSNLERLMNKRDMSDSELAELVDVNRTTVTRWRKGIRSPKLDKLPEIANVFGVKPLDLIHDMDDSKIIEEIHNVSS
QLTPPRQSNVLKYATNQLEEQNNDSDNLVDFNSYIQEKSEVDIYGCASAGIGERLYNEPISKEFVRGYVPAHDIALKVNG
DSMEPLFKNGQIIFIEKSHTIKDGQIGVFIINGDAYVKKVYVEDNRLTLVSLNKKYKDLHFYDNESVRLVGKVIL

Nucleotide

• Length: 708 bp

>NTDB_id=224040 RL05_RS03420 WP_000094093.1 572059..572766(+) (irvR) [Staphylococcus aureus strain FDAARGOS_47]
ATGAGTTCATTTTCTTCGAATCTAGAACGTCTGATGAACAAAAGAGATATGAGTGATAGTGAATTAGCAGAATTAGTAGA
TGTAAATAGAACAACAGTCACAAGATGGAGAAAGGGAATTAGAAGTCCAAAACTAGATAAATTACCTGAAATAGCTAATG
TTTTTGGAGTTAAACCCTTAGATTTAATACATGATATGGATGATTCGAAAATTATTGAAGAAATTCATAACGTGTCATCT
CAACTCACGCCTCCAAGACAAAGCAATGTACTAAAATATGCGACTAATCAATTAGAAGAGCAAAATAATGACAGTGATAA
TCTGGTAGATTTCAATTCTTACATTCAAGAAAAATCCGAAGTGGATATATATGGTTGTGCGTCTGCTGGTATTGGTGAAA
GATTATATAACGAGCCTATTTCAAAAGAATTCGTAAGAGGTTATGTCCCCGCACATGATATAGCTTTAAAAGTAAATGGA
GACTCAATGGAGCCGTTATTTAAAAATGGACAAATTATATTCATTGAAAAATCTCACACTATCAAAGATGGACAAATAGG
CGTCTTTATTATAAATGGAGATGCTTACGTAAAGAAGGTTTATGTAGAAGATAACAGATTAACGTTGGTTTCTTTAAATA
AAAAGTATAAAGATTTACATTTTTATGATAATGAAAGTGTGAGGTTAGTTGGAAAAGTTATTTTATAG

Domains

Predicted by InterProScan.

• Peptidase S24-like (Peptidase_S24) (123-234)

• Helix-turn-helix (HTH_3) (8-61)

3D structure

• AlphaFold DB: A0A1D4DWM6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
irvR	Streptococcus mutans UA159	30.769	100	0.374