Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilH   Type   Machinery gene
Locus tag   NMB_RS04595 Genome accession   NC_003112
Coordinates   907408..908076 (+) Length   222 a.a.
NCBI ID   WP_002230433.1    Uniprot ID   Q9JZV4
Organism   Neisseria meningitidis MC58     
Function   type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 902408..913076
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NMB_RS12145 - 903100..903207 (+) 108 Protein_876 IS5/IS1182 family transposase -
  NMB_RS04575 (NMB0882) - 903252..903584 (+) 333 WP_002225363.1 hypothetical protein -
  NMB_RS04580 (NMB0883) - 903916..904425 (+) 510 WP_002213852.1 isoprenylcysteine carboxyl methyltransferase family protein -
  NMB_RS04585 (NMB0884) - 904942..905529 (-) 588 WP_002220670.1 superoxide dismutase -
  NMB_RS04590 (NMB0885) dnaB 905693..907099 (+) 1407 WP_002225362.1 replicative DNA helicase -
  NMB_RS04595 (NMB0886) pilH 907408..908076 (+) 669 WP_002230433.1 GspH/FimT family pseudopilin Machinery gene
  NMB_RS04600 (NMB0887) pilV 908100..908708 (+) 609 WP_061706010.1 type IV pilus modification protein PilV Regulator
  NMB_RS04605 (NMB0888) pilJ 908705..909646 (+) 942 WP_002244084.1 PilW family protein Machinery gene
  NMB_RS04610 (NMB0889) pilK 909625..910218 (+) 594 WP_002244085.1 pilus assembly PilX family protein Machinery gene
  NMB_RS04615 (NMB0890) pilX 910223..910696 (+) 474 WP_002225356.1 PilX family type IV pilin Machinery gene
  NMB_RS04620 (NMB0892) - 912465..912833 (-) 369 Protein_886 AzlC family ABC transporter permease -

Sequence

Protein


Download         Length: 222 a.a.        Molecular weight: 24955.58 Da        Isoelectric Point: 9.7285

>NTDB_id=22351 NMB_RS04595 WP_002230433.1 907408..908076(+) (pilH) [Neisseria meningitidis MC58]
MCTRKQQGFTLTELLIVMVIAAIMAMIALPNMSQWIASRRIASHAERIANLLRFSRGEAVRLNLPVYICPVQVKKDGTPN
NKCDSGKKGQGMLAFGDKNGNKGYDNDTEDVLLRSVVLNDDINDKRINYAFNHIAFGQTQPTTDRVVWTFNQNGTFGYTK
DQHLTKQSSFFYSDGYIQIVLTDAKAVSADEKKFRSAVVLINSSGRVEVCPRGDRRTMCQYK

Nucleotide


Download         Length: 669 bp        

>NTDB_id=22351 NMB_RS04595 WP_002230433.1 907408..908076(+) (pilH) [Neisseria meningitidis MC58]
ATGTGTACACGAAAACAACAAGGTTTCACGCTAACAGAGCTGCTCATCGTGATGGTCATTGCAGCCATTATGGCGATGAT
AGCCCTCCCCAATATGAGCCAATGGATTGCATCCCGCCGCATTGCCAGTCACGCGGAGCGGATTGCCAACCTTTTGCGTT
TCTCCAGGGGCGAAGCCGTCCGGCTCAATCTCCCTGTCTATATCTGTCCTGTTCAAGTTAAAAAAGACGGTACGCCCAAC
AATAAATGTGACTCCGGCAAGAAGGGGCAGGGAATGTTGGCTTTCGGCGACAAAAACGGCAATAAGGGATATGACAATGA
TACGGAGGATGTTCTTCTCCGCAGTGTGGTATTGAATGATGATATCAATGATAAGCGGATTAATTATGCCTTCAACCATA
TCGCTTTCGGTCAGACTCAGCCGACCACCGACCGTGTAGTTTGGACATTCAATCAAAACGGGACGTTCGGTTATACGAAA
GACCAGCATCTTACAAAACAATCCAGCTTTTTTTATTCTGACGGTTATATCCAAATCGTGTTGACAGATGCGAAGGCGGT
TTCTGCCGATGAAAAGAAATTCCGTTCGGCGGTGGTTTTGATTAACAGCAGCGGCAGGGTCGAAGTTTGCCCTAGGGGTG
ATCGGCGTACTATGTGCCAGTATAAATAA

Domains

Predicted by InterProScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(4-29)

Type II transport protein GspH (GspH)

(44-205)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q9JZV4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilH Neisseria gonorrhoeae MS11

81.9

99.55

0.815