Detailed information NTG0022331

Bioinformatically predicted

Overview

• Name: kpsS
• Type: Regulator
• Locus tag: NMB_RS00445
• Genome accession: NC_003112
• Coordinates: 93566..94825 (+)
• Length: 419 a.a.
• NCBI ID: WP_002223278.1
• Uniprot ID: Q05014
• Organism: Neisseria meningitidis MC58
• Function: repress natural transformation (predicted from homology) Competence regulation

Genomic Context

Location: 88566..99825

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NMB_RS00425 (NMB0079)	rfbB	88701..89768 (+)	1068	WP_002224748.1	dTDP-glucose 4,6-dehydratase	-
NMB_RS00430 (NMB0080)	rfbA	89831..90697 (+)	867	WP_002224747.1	glucose-1-phosphate thymidylyltransferase RfbA	-
NMB_RS00435 (NMB0081)	rfbC	90751..91290 (+)	540	WP_002224755.1	dTDP-4-dehydrorhamnose 3,5-epimerase	-
NMB_RS00440 (NMB0082)	-	91315..93429 (+)	2115	WP_002224756.1	capsular polysaccharide biosynthesis protein	-
NMB_RS00445 (NMB0083)	kpsS	93566..94825 (+)	1260	WP_002223278.1	capsule biosynthesis protein	Regulator
NMB_RS00450 (NMB0084)	-	95192..96597 (+)	1406	Protein_85	tetratricopeptide repeat protein	-
NMB_RS00455 (NMB0085)	gltS	96815..98029 (+)	1215	WP_002224758.1	sodium/glutamate symporter	-
NMB_RS00460 (NMB0086)	-	98128..99144 (+)	1017	WP_002215314.1	lysozyme inhibitor LprI family protein	-
NMB_RS00465 (NMB0087)	-	99155..99352 (+)	198	WP_002215316.1	hypothetical protein	-
NMB_RS11285	-	99370..99519 (+)	150	WP_033908521.1	hypothetical protein	-

Sequence

Protein

• Length: 419 a.a.
• Molecular weight: 48701.63 Da
• Isoelectric Point: 9.0748

>NTDB_id=22331 NMB_RS00445 WP_002223278.1 93566..94825(+) (kpsS) [Neisseria meningitidis MC58]
MKQTVLKNNLQNLLESAENILLLQGPVGDFFLRLADWLTANGKTVHKFNFNAGDDYFYPPTQAHTVVFNDNYDAFPEFLQ
EYITQHHIQAVVCFGDTRPYHVIAKRIANENQASFWAFEEGYFRPYYITLEKDGVNAFSPLPRRADFFLEQFPKLAQQEY
KAPTPVHGGFTPMAKNAIRYYIELFRNPRKYPDYIHHRAPNAGHYLKPWSLSILKRLNYYIEDIQIAKRVEAGKYGKFFI
VPLQVFNDSQVRIHCDFPSVRSFLLHVLSSFAEHAPADTNIIIKHHPMDRGFIDYWRDIKRFIKEHPELKGRVIYVHDVP
LPVFLRHGLGMVTINSTSGLSGLIHNMPVKVLGRAYYDIPGITDQNTLAEFWNHPTPPDKELFHAYRMYHLNVTQINGNF
YSQVFFPNKKTSNSSTPVI

Nucleotide

• Length: 1260 bp

>NTDB_id=22331 NMB_RS00445 WP_002223278.1 93566..94825(+) (kpsS) [Neisseria meningitidis MC58]
ATGAAACAGACCGTCCTCAAAAATAACCTGCAAAACCTGCTTGAAAGCGCAGAAAATATCCTGCTGCTTCAAGGCCCTGT
CGGCGATTTTTTTCTGCGCCTTGCCGACTGGCTGACTGCAAACGGCAAAACCGTACATAAATTCAACTTTAATGCAGGCG
ACGACTATTTTTATCCGCCCACTCAAGCGCATACCGTTGTTTTTAACGACAACTACGATGCCTTTCCTGAGTTTTTGCAA
GAATACATCACTCAACATCACATCCAGGCCGTTGTCTGCTTTGGCGACACACGCCCTTATCACGTCATTGCAAAACGCAT
TGCAAACGAAAACCAAGCCAGTTTCTGGGCGTTTGAAGAAGGCTATTTCCGCCCCTACTACATCACCTTAGAAAAAGACG
GCGTCAACGCATTTTCCCCGTTGCCGCGCCGTGCCGACTTTTTTCTTGAACAATTCCCTAAGCTTGCCCAGCAAGAATAT
AAAGCGCCAACGCCGGTACACGGCGGTTTTACGCCCATGGCAAAAAACGCTATCCGTTACTATATCGAGTTGTTCCGCAA
TCCACGCAAATACCCCGACTACATCCACCACCGCGCACCCAATGCCGGCCATTACCTCAAACCGTGGTCGCTCTCCATCC
TCAAGCGTTTGAACTACTATATTGAAGACATCCAAATCGCCAAACGTGTGGAAGCAGGCAAATACGGCAAGTTTTTTATT
GTTCCCTTACAGGTATTCAACGACAGCCAAGTCCGTATCCATTGCGACTTTCCCAGCGTCCGCAGCTTCCTGCTCCATGT
TTTGAGTTCATTTGCCGAGCACGCGCCTGCCGATACCAACATCATCATCAAGCATCATCCGATGGACCGCGGTTTTATCG
ACTACTGGCGCGACATTAAACGCTTTATCAAAGAACACCCCGAACTCAAAGGCCGTGTGATTTATGTCCATGATGTCCCC
CTGCCCGTTTTCCTGCGCCACGGTCTCGGCATGGTCACCATCAACAGCACCAGCGGCCTGTCCGGACTGATTCACAATAT
GCCAGTTAAGGTTCTCGGCCGTGCCTATTATGATATTCCCGGCATTACTGACCAAAATACCTTGGCAGAATTTTGGAATC
ATCCGACACCGCCTGACAAAGAGCTGTTCCATGCCTACCGAATGTACCACCTCAACGTGACCCAAATTAACGGCAACTTC
TACAGTCAGGTGTTTTTCCCCAACAAAAAAACCTCCAACTCTTCCACACCAGTAATCTGA

Domains

Predicted by InterProScan.

• Capsule polysaccharide biosynthesis protein (Capsule_synth) (89-401)

3D structure

• AlphaFold DB: Q05014

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
kpsS	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	38.579	94.033	0.363