Detailed information NTG0223284

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: RK77_RS12795
• Genome accession: NZ_CP026064
• Coordinates: 2484418..2485692 (-)
• Length: 424 a.a.
• NCBI ID: WP_001279338.1
• Uniprot ID: A0A0H2XGV4
• Organism: Staphylococcus aureus strain FDAARGOS_19
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 2479418..2490692

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
RK77_RS12780 (RK77_012780)	-	2481704..2481796 (+)	93	WP_001789987.1	hypothetical protein	-
RK77_RS12785 (RK77_012785)	-	2481776..2482681 (-)	906	WP_000184370.1	transglycosylase domain-containing protein	-
RK77_RS12790 (RK77_012790)	tyrS	2483062..2484324 (+)	1263	WP_000186037.1	tyrosine--tRNA ligase	-
RK77_RS12795 (RK77_012795)	htrA	2484418..2485692 (-)	1275	WP_001279338.1	trypsin-like peptidase domain-containing protein	Regulator
RK77_RS12800 (RK77_012800)	-	2485864..2486481 (+)	618	WP_000287588.1	1-acyl-sn-glycerol-3-phosphate acyltransferase	-
RK77_RS12805 (RK77_012805)	nagE	2486609..2488075 (+)	1467	WP_000276367.1	N-acetylglucosamine-specific PTS transporter subunit IIBC	-
RK77_RS12810 (RK77_012810)	-	2488182..2489312 (+)	1131	WP_000721707.1	HAD family hydrolase	-
RK77_RS12815 (RK77_012815)	-	2489273..2489368 (-)	96	WP_031789489.1	hypothetical protein	-

Sequence

Protein

• Length: 424 a.a.
• Molecular weight: 45802.98 Da
• Isoelectric Point: 9.9696

>NTDB_id=223284 RK77_RS12795 WP_001279338.1 2484418..2485692(-) (htrA) [Staphylococcus aureus strain FDAARGOS_19]
MSDFNHTDHSTTNHSQTPRYRRPKFPWFKTVIVALIAGIIGALLVLGIGKVLNSTILNKDGSTVQTTNNKGGNQLDGQSK
KFGTVHEMIKSVSPTIVGVINMQKASSVDDLLKGKSSKPSEAGVGSGVIYQINNNSAYIVTNNHVIDGANEIRVQLHNKK
QVKAKLVGKDAVTDIAVLKIENTKGIKAIQFANSSKVQTGDSVFAMGNPLGLQFANSVTSGIISASERTIDAETTGGNTK
VSVLQTDAAINPGNSGGALVDINGNLVGINSMKIAATQVEGIGFAIPSNEVKVTIEQLVKHGKIDRPSIGIGLINLKDIP
EEEREQLHTDREDGIYVAKADSDIDLKKGDIITEIDGKKIKDDVDLRSYLYENKKPGESVTVTVIRDGKTKEVKVKLKQQ
KEQPKRQSRSERQSPGQGDRDFFR

Nucleotide

• Length: 1275 bp

>NTDB_id=223284 RK77_RS12795 WP_001279338.1 2484418..2485692(-) (htrA) [Staphylococcus aureus strain FDAARGOS_19]
ATGTCAGATTTTAATCATACAGATCATTCTACAACAAACCATAGCCAAACACCTAGATACAGAAGACCTAAATTTCCATG
GTTTAAAACAGTCATCGTTGCATTGATTGCTGGAATTATTGGTGCACTTCTAGTACTTGGTATAGGCAAAGTATTAAATA
GTACAATTTTAAATAAAGATGGTTCAACTGTCCAGACAACAAATAATAAAGGTGGCAATCAATTAGACGGTCAAAGCAAG
AAATTCGGTACCGTTCATGAAATGATAAAATCTGTCTCCCCTACAATTGTTGGAGTTATTAACATGCAAAAAGCATCAAG
TGTAGACGACTTATTAAAAGGCAAATCATCTAAACCATCTGAAGCTGGAGTAGGTTCAGGTGTTATCTATCAAATAAACA
ACAATTCAGCTTATATCGTTACAAACAATCATGTTATTGATGGCGCAAATGAAATTAGAGTCCAATTACATAATAAAAAA
CAAGTTAAAGCGAAATTAGTTGGTAAAGATGCAGTAACTGATATTGCTGTACTTAAAATTGAAAATACAAAAGGTATTAA
AGCGATTCAATTTGCCAACTCTTCAAAAGTACAAACTGGCGATAGCGTATTCGCAATGGGTAACCCATTAGGATTACAAT
TTGCTAACTCTGTAACATCTGGTATCATTTCAGCAAGCGAACGTACGATTGACGCTGAGACAACTGGTGGCAATACAAAA
GTCAGCGTTCTTCAAACAGATGCTGCTATTAACCCAGGTAACTCAGGTGGCGCATTAGTAGATATTAATGGTAATTTAGT
TGGTATTAACTCAATGAAAATTGCTGCGACACAAGTTGAAGGTATCGGGTTTGCTATTCCAAGTAATGAAGTTAAAGTAA
CAATTGAACAACTTGTAAAACATGGTAAAATTGACCGCCCTTCGATTGGTATTGGTTTAATTAATTTGAAAGATATTCCT
GAAGAAGAGCGCGAGCAACTTCATACTGATAGAGAAGACGGTATTTATGTCGCCAAAGCTGATAGTGATATTGATCTTAA
AAAAGGTGATATTATTACAGAAATTGATGGCAAGAAAATTAAAGATGATGTTGATTTAAGAAGCTATTTATATGAAAATA
AAAAACCTGGTGAATCAGTCACTGTTACCGTTATCCGTGATGGTAAAACAAAAGAAGTTAAAGTGAAATTAAAACAACAA
AAAGAACAACCAAAACGTCAAAGCCGATCAGAACGTCAATCACCTGGCCAAGGCGATAGAGATTTCTTTAGATAA

Domains

Predicted by InterProScan.

• Trypsin-like peptidase domain (Trypsin_2) (125-269)

• PDZ domain (PDZ_2) (307-397)

3D structure

• AlphaFold DB: A0A0H2XGV4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mutans UA159	39.055	94.811	0.37