Detailed information NTG0223146

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: A6J85_RS00535
• Genome accession: NZ_CP020450
• Coordinates: 99781..100824 (-)
• Length: 347 a.a.
• NCBI ID: WP_046165911.1
• Uniprot ID: -
• Organism: Streptococcus gordonii strain FDAARGOS_257
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 94781..105824

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A6J85_RS00510 (A6J85_00505)	-	95280..95591 (-)	312	WP_011074524.1	chorismate mutase	-
A6J85_RS00515 (A6J85_00510)	trpB	95899..97080 (-)	1182	WP_008809124.1	tryptophan synthase subunit beta	-
A6J85_RS00520 (A6J85_00515)	-	97448..97987 (-)	540	WP_082307116.1	VanZ family protein	-
A6J85_RS00525 (A6J85_00520)	rlmN	97974..99062 (-)	1089	WP_002911938.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
A6J85_RS00530 (A6J85_00525)	-	99072..99608 (-)	537	WP_053794854.1	YutD family protein	-
A6J85_RS00535 (A6J85_00530)	sepM	99781..100824 (-)	1044	WP_046165911.1	SepM family pheromone-processing serine protease	Regulator
A6J85_RS00540 (A6J85_00535)	coaD	100811..101305 (-)	495	WP_082307117.1	pantetheine-phosphate adenylyltransferase	-
A6J85_RS00545 (A6J85_00540)	rsmD	101295..101843 (-)	549	WP_185760801.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
A6J85_RS00550 (A6J85_00545)	-	101916..102404 (-)	489	WP_082307119.1	YcxB family protein	-
A6J85_RS00555 (A6J85_00550)	-	102547..103224 (+)	678	WP_082307120.1	XRE family transcriptional regulator	-
A6J85_RS00560 (A6J85_00555)	-	103229..104644 (+)	1416	WP_082307121.1	Y-family DNA polymerase	-
A6J85_RS00565 (A6J85_00560)	-	104641..105015 (+)	375	WP_002896227.1	hypothetical protein	-
A6J85_RS00570 (A6J85_00565)	-	104993..105286 (+)	294	WP_048775740.1	DUF5960 family protein	-
A6J85_RS00575 (A6J85_00570)	-	105368..105652 (-)	285	WP_045634732.1	type II toxin-antitoxin system RelE/ParE family toxin	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 38023.59 Da
• Isoelectric Point: 6.1221

>NTDB_id=223146 A6J85_RS00535 WP_046165911.1 99781..100824(-) (sepM) [Streptococcus gordonii strain FDAARGOS_257]
MKKISVYKWPIIIFSSLILLVVSLTVPLPYYIEVPGGAEDIRKVLLVDNKEDKEAGAYEFVTVGVQRATFAHLVYAWLTD
FTDIYSAEEMTGGSSDQEFIRINQFYMETSQNMAKYQGLKTAGKDISMKYLGVYVLQVAKDSTFKGILNIADTVTGVNDK
TFDSSEELVKYVNSQKLGDKVKVTYQEDGQEKSATGKIIKLENGKNGIGISLIDRTEVTSNIPIEFTTEGIGGPSAGLMF
SLSIYTQLADPTLRDGRVIAGTGSINRDGEVGDIGGIDKKVVSAAKSGASIFFAPNNPVTKEMKKIDPKAKTNYETAVEA
AKKIKTDMKIVPVKTLQDAIDYLKNNK

Nucleotide

• Length: 1044 bp

>NTDB_id=223146 A6J85_RS00535 WP_046165911.1 99781..100824(-) (sepM) [Streptococcus gordonii strain FDAARGOS_257]
ATGAAAAAAATTAGTGTTTATAAATGGCCCATTATTATTTTTTCAAGCTTGATTTTGCTTGTCGTATCTTTGACGGTTCC
TTTACCATACTATATTGAAGTTCCTGGCGGTGCAGAGGATATTCGAAAGGTCTTGCTGGTTGATAATAAGGAAGATAAGG
AAGCTGGGGCCTACGAGTTTGTGACAGTTGGAGTTCAACGAGCAACCTTTGCTCATCTTGTCTATGCGTGGCTGACTGAT
TTCACGGATATCTACTCTGCCGAAGAAATGACTGGTGGATCATCGGACCAAGAATTTATTCGAATCAATCAGTTTTATAT
GGAAACATCCCAAAACATGGCCAAGTATCAAGGCTTGAAAACGGCTGGAAAAGATATTAGCATGAAATATCTGGGCGTCT
ATGTTTTGCAAGTCGCAAAAGATTCGACTTTTAAGGGAATTTTGAATATTGCGGACACGGTAACGGGAGTTAATGACAAG
ACTTTTGACAGTTCAGAAGAATTGGTGAAATATGTTAATTCTCAGAAATTAGGAGATAAGGTTAAGGTCACTTACCAGGA
AGATGGCCAAGAAAAATCAGCGACTGGAAAGATTATTAAGCTAGAAAATGGTAAAAACGGAATCGGTATTAGCTTAATCG
ATAGAACAGAAGTTACTAGTAACATTCCAATTGAATTTACCACAGAAGGCATTGGAGGACCTAGTGCGGGTCTCATGTTT
AGCTTGTCAATCTATACACAACTTGCAGATCCAACTTTACGAGATGGGCGTGTGATTGCAGGTACCGGAAGTATCAATCG
TGATGGAGAAGTTGGTGATATTGGTGGGATTGATAAGAAAGTCGTCTCAGCTGCTAAAAGTGGGGCCAGCATCTTCTTTG
CTCCCAATAATCCTGTAACAAAAGAAATGAAAAAAATCGATCCAAAAGCAAAGACGAACTATGAAACAGCAGTTGAGGCT
GCTAAAAAGATTAAAACAGATATGAAAATTGTTCCTGTTAAAACCTTACAGGATGCCATTGATTATCTTAAGAACAATAA
ATAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (129-195)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (232-315)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	61.272	99.712	0.611