Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpE   Type   Regulator
Locus tag   A6J85_RS00335 Genome accession   NZ_CP020450
Coordinates   63315..65576 (+) Length   753 a.a.
NCBI ID   WP_082307105.1    Uniprot ID   -
Organism   Streptococcus gordonii strain FDAARGOS_257     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 58315..70576
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A6J85_RS00300 (A6J85_00300) - 58439..58651 (-) 213 WP_008809086.1 exodeoxyribonuclease VII small subunit -
  A6J85_RS00305 (A6J85_00305) xseA 58629..59969 (-) 1341 WP_082307103.1 exodeoxyribonuclease VII large subunit -
  A6J85_RS00315 (A6J85_00315) - 60125..60967 (-) 843 WP_105165070.1 NAD(P)H-hydrate dehydratase -
  A6J85_RS00320 (A6J85_00320) - 61075..61848 (-) 774 WP_082307104.1 HAD hydrolase family protein -
  A6J85_RS00325 (A6J85_00325) - 61845..62699 (-) 855 WP_061583573.1 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase -
  A6J85_RS00330 (A6J85_00330) - 62832..63062 (-) 231 WP_008809091.1 DUF1797 family protein -
  A6J85_RS00335 (A6J85_00335) clpE 63315..65576 (+) 2262 WP_082307105.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  A6J85_RS00340 (A6J85_00340) - 65628..66233 (-) 606 WP_082307106.1 GyrI-like domain-containing protein -
  A6J85_RS00345 (A6J85_00345) - 66293..67183 (-) 891 WP_082307107.1 YafY family protein -
  A6J85_RS00350 (A6J85_00350) - 67343..67795 (+) 453 WP_105165071.1 NUDIX hydrolase -
  A6J85_RS00355 (A6J85_00355) - 67894..68193 (+) 300 WP_045773849.1 DUF1827 family protein -
  A6J85_RS00360 (A6J85_00360) - 68230..68667 (-) 438 WP_082307108.1 GNAT family N-acetyltransferase -
  A6J85_RS00365 (A6J85_00365) - 68690..69145 (+) 456 WP_045501900.1 MarR family winged helix-turn-helix transcriptional regulator -

Sequence

Protein


Download         Length: 753 a.a.        Molecular weight: 83887.91 Da        Isoelectric Point: 4.9810

>NTDB_id=223144 A6J85_RS00335 WP_082307105.1 63315..65576(+) (clpE) [Streptococcus gordonii strain FDAARGOS_257]
MLCQNCKINESTIHLYTNVNGKKQQVDLCQNCYQIMKTDPNNSLLGGLTNMNNHNMDPFDDFFNHLGNFQGPKDSTPPTQ
SGGSYGGGNYGPGSNNQRPQSASNKPKGLLEEFGINVTEIARRGDIDPVIGRDDEIRRVIEILNRRTKNNPVLIGEPGVG
KTAVVEGLAQKIVDSDVPQKLQGKEVIRLDVVSLVQGTGIRGQFEERMQKLMDEIRNRNDIILFIDEIHEIVGAGSAGDG
NMDAGNILKPALARGELQLVGATTLNEYRIIEKDAALERRMQPVKVDEPTVEETITILKGIQKKYEDYHHVRYTDEAIEA
AAILSNRYIQDRFLPDKAIDLLDESGSKMNLTLNFVDPKEIDRRLIEAENLKTQATRDEDYEKAAYFRDQIAKYKEMQTA
KIDEQDTPIISEKEIEAIVEQKTNIPVGDLKEKEQSQLIHLASDLKSHVIGQDDAVDKIAKAIRRNRVGLGSPNRPIGSF
LFVGPTGVGKTELSKQLAIELFGSADSMIRFDMSEYMEKHSVAKLVGAPPGYVGYEEAGQLTERVRRNPYSLILLDEVEK
AHPDVMHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKVEASVGFGAAREGRTNSVLGELGNFFSPEFMNRFDGI
IEFKALSKDNLLQIVDLMLEDVNNRLASNDIHLDVTTKVKEKLVDLGYDPKMGARPLRRTIQDHIEDAITDYYLEHPTDK
DLKAIMTSNGKIIIKGKQKAELDQTSDISTSSD

Nucleotide


Download         Length: 2262 bp        

>NTDB_id=223144 A6J85_RS00335 WP_082307105.1 63315..65576(+) (clpE) [Streptococcus gordonii strain FDAARGOS_257]
ATGCTTTGTCAAAACTGTAAAATCAATGAATCTACCATTCATTTATACACTAATGTAAATGGTAAAAAACAACAAGTTGA
CCTCTGTCAAAATTGCTATCAGATTATGAAAACTGATCCAAATAACTCTCTTTTGGGTGGATTGACGAACATGAATAATC
ATAATATGGATCCTTTTGATGATTTCTTTAATCATCTGGGGAATTTCCAAGGACCAAAGGATTCTACCCCTCCAACTCAG
TCAGGTGGTAGTTATGGAGGGGGCAACTATGGTCCTGGTTCTAACAACCAGCGTCCTCAGTCAGCCTCCAATAAACCAAA
AGGTCTTTTGGAAGAGTTTGGTATTAATGTTACAGAAATTGCTCGGCGTGGTGATATTGATCCAGTGATTGGACGAGATG
ATGAAATTCGTCGTGTTATAGAAATTCTCAATCGCCGAACTAAGAATAATCCAGTCCTTATTGGCGAACCTGGTGTCGGG
AAGACTGCTGTTGTAGAGGGCTTGGCACAGAAAATAGTCGATAGTGACGTTCCTCAAAAACTGCAAGGAAAAGAGGTCAT
TCGACTCGATGTTGTCAGCCTTGTTCAAGGAACTGGTATTCGCGGGCAATTTGAAGAACGAATGCAAAAACTCATGGATG
AGATTCGCAATCGCAATGATATCATTCTCTTTATTGATGAAATCCATGAAATTGTTGGAGCTGGCTCTGCGGGCGACGGT
AATATGGATGCTGGAAATATTCTCAAACCTGCTCTTGCTCGAGGTGAACTTCAACTGGTTGGAGCTACTACTCTCAACGA
ATACCGAATCATTGAAAAGGATGCAGCATTAGAAAGACGGATGCAACCAGTCAAGGTAGATGAACCAACTGTAGAAGAAA
CGATCACAATTCTAAAGGGAATTCAAAAGAAATACGAAGATTACCACCATGTTCGCTACACAGATGAGGCTATTGAAGCT
GCAGCCATCCTATCTAATCGTTATATTCAGGACCGTTTCCTTCCCGATAAAGCTATTGATCTTTTGGATGAATCAGGATC
TAAGATGAACCTAACCCTCAATTTTGTTGATCCAAAAGAAATTGACAGACGCTTGATAGAGGCTGAAAATCTGAAAACAC
AGGCCACTCGCGATGAAGATTACGAAAAAGCAGCCTACTTCCGCGACCAAATTGCCAAATATAAGGAAATGCAAACTGCT
AAAATAGATGAACAAGATACTCCTATCATCAGTGAGAAGGAGATCGAAGCTATTGTCGAGCAAAAAACAAATATTCCTGT
TGGGGATTTGAAGGAAAAAGAGCAGTCTCAGCTTATTCATTTAGCCAGTGATTTGAAGTCTCATGTCATTGGGCAGGATG
ATGCTGTTGATAAGATTGCAAAAGCCATCCGTCGCAATCGTGTGGGATTAGGCAGTCCAAACCGACCAATCGGAAGTTTT
CTTTTTGTTGGACCTACAGGTGTCGGAAAAACTGAACTTTCCAAACAATTGGCCATCGAACTTTTTGGCTCTGCCGATAG
CATGATTCGTTTTGATATGAGTGAATACATGGAAAAACATAGCGTTGCCAAACTTGTGGGAGCACCTCCAGGCTACGTTG
GCTATGAAGAAGCAGGGCAGTTGACTGAACGTGTTCGTCGTAATCCATACTCACTCATTCTCTTAGATGAGGTGGAAAAA
GCTCATCCAGATGTCATGCATATGTTCTTACAAGTCCTAGATGATGGACGTTTGACTGATGGTCAAGGCAGGACAGTCAG
CTTCAAAGATACCATTATTATCATGACTTCCAATGCAGGAACTGGCAAAGTAGAAGCTAGCGTTGGCTTTGGTGCTGCTC
GAGAAGGTCGGACAAATTCTGTCTTAGGTGAGTTAGGTAACTTCTTTAGTCCAGAATTCATGAATCGATTTGATGGCATC
ATTGAATTCAAGGCATTAAGCAAGGATAATCTCTTACAGATTGTGGATCTAATGCTGGAAGATGTTAATAATCGACTCGC
TAGCAACGATATTCATCTAGATGTAACAACTAAAGTCAAGGAAAAACTAGTTGATCTTGGCTACGATCCTAAGATGGGGG
CACGACCACTTCGCCGAACTATTCAAGATCATATTGAAGATGCTATTACGGACTATTACCTAGAACATCCGACAGATAAG
GATTTAAAAGCAATCATGACTAGCAATGGCAAGATTATAATCAAGGGCAAACAGAAAGCTGAGCTTGATCAAACAAGTGA
CATCAGCACTAGCTCGGATTGA

Domains

Predicted by InterproScan.

AAA lid domain (AAA_lid_9)

(290-387)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(646-718)

ATPase family associated with various cellular activities (AAA) (AAA)

(152-271)

AAA domain (Cdc48 subfamily) (AAA_2)

(475-638)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpE Streptococcus pneumoniae Rx1

86.729

99.07

0.859
  clpE Streptococcus pneumoniae D39

86.729

99.07

0.859
  clpE Streptococcus pneumoniae R6

86.729

99.07

0.859
  clpE Streptococcus pneumoniae TIGR4

86.595

99.07

0.858
  clpE Streptococcus mutans UA159

85.121

99.07

0.843
  clpC Lactococcus lactis subsp. cremoris KW2

77.454

100

0.776
  clpC Bacillus subtilis subsp. subtilis str. 168

50.74

89.774

0.456
  clpC Streptococcus pneumoniae Rx1

47.68

83.001

0.396
  clpC Streptococcus pneumoniae D39

47.68

83.001

0.396
  clpC Streptococcus mutans UA159

46.562

84.993

0.396
  clpC Streptococcus pneumoniae TIGR4

47.52

83.001

0.394
  clpC Streptococcus thermophilus LMD-9

44.985

87.384

0.393
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

46.761

84.064

0.393
  clpC Streptococcus thermophilus LMG 18311

45.038

86.985

0.392

Multiple sequence alignment