Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpE   Type   Regulator
Locus tag   A6J72_RS08325 Genome accession   NZ_CP020433
Coordinates   1642816..1645068 (-) Length   750 a.a.
NCBI ID   WP_082312206.1    Uniprot ID   -
Organism   Streptococcus intermedius strain FDAARGOS_233     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1637816..1650068
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A6J72_RS08295 (A6J72_08280) - 1637820..1638074 (+) 255 WP_003077046.1 hypothetical protein -
  A6J72_RS08300 (A6J72_08285) - 1638086..1640140 (+) 2055 WP_082312204.1 sodium:proton antiporter -
  A6J72_RS08305 (A6J72_08290) - 1640215..1640514 (-) 300 WP_003071940.1 DUF1827 family protein -
  A6J72_RS08310 (A6J72_08295) - 1640578..1641027 (-) 450 WP_003071942.1 NUDIX hydrolase -
  A6J72_RS08315 (A6J72_08300) - 1641184..1642077 (+) 894 WP_105255949.1 YafY family protein -
  A6J72_RS08320 (A6J72_08305) - 1642137..1642742 (+) 606 WP_082312205.1 GyrI-like domain-containing protein -
  A6J72_RS08325 (A6J72_08310) clpE 1642816..1645068 (-) 2253 WP_082312206.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  A6J72_RS08330 (A6J72_08315) - 1645308..1645538 (+) 231 WP_003023686.1 DUF1797 family protein -
  A6J72_RS08335 (A6J72_08320) - 1645691..1646233 (+) 543 WP_003077029.1 ClbS/DfsB family four-helix bundle protein -
  A6J72_RS10010 - 1646275..1646406 (+) 132 WP_263969849.1 hypothetical protein -
  A6J72_RS08345 (A6J72_08330) - 1646678..1648066 (-) 1389 WP_003071961.1 ABC transporter permease -
  A6J72_RS08350 (A6J72_08335) - 1648090..1648737 (-) 648 WP_003030192.1 ABC transporter ATP-binding protein -
  A6J72_RS08355 (A6J72_08340) - 1648749..1650041 (-) 1293 WP_003076587.1 ABC transporter permease -

Sequence

Protein


Download         Length: 750 a.a.        Molecular weight: 83862.03 Da        Isoelectric Point: 5.1600

>NTDB_id=223029 A6J72_RS08325 WP_082312206.1 1642816..1645068(-) (clpE) [Streptococcus intermedius strain FDAARGOS_233]
MLCQNCKINESTIHLYTNVNGKQHQVDLCQNCYQIMKTDPNNALFRGMTNMNNQNNLDPFDDFFSNIGNFQNHQEPQTPP
TQSGGGYGNGGYGSNQGNSTRQQAPQQPKGLLEEFGINVTEFARRGEIDPVIGRDEEIVRVIEILNRRTKNNPVLIGEPG
VGKTAVVEGLAQKIVDGDVPHKLQGKEVIRLDVVSLVQGTGIRGQFEERMQKLMNEIRSRQDVILFIDEIHEIVGAGSAG
DGNMDAGNILKPALARGELQLVGATTLNEYRIIEKDAALERRMQPVKVDEPTVEETITILKGIQKKYEDYHHVKYTDDAI
EAAAVLSNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFVDPKVIDQRLVEAENLKAQATRDEDFEKAAYFRDQIAKYKEMQ
QNKMADQDTPLISEKTIEHIIEQKTNIPVGDLKEKEQSQLISLADDLKTHVIGQDDAVDKIAKAIRRNRVGLGTPNRPIG
SFLFVGPTGVGKTELSKQLAIELFGSADSMIRFDMSEYMEKHSVAKLVGAPPGYVGYEEAGQLTERVRRNPYSLILLDEI
EKAHPDVMHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKVEANVGFGAAREGRTNSVIGELGNFFSPEFMNRFD
GIIEFKSLSKENLLQIVDLMLKDVNERLATNDIYLDVTDKVKEKLVNLGYDPKMGARPLRRTIQDHIEDAITDYYLEHPS
DKELKAIMTSNGKIVIKPAKKSENKSNKES

Nucleotide


Download         Length: 2253 bp        

>NTDB_id=223029 A6J72_RS08325 WP_082312206.1 1642816..1645068(-) (clpE) [Streptococcus intermedius strain FDAARGOS_233]
ATGCTTTGTCAAAACTGTAAAATAAATGAATCTACCATTCATCTTTACACAAATGTTAATGGGAAACAACATCAAGTTGA
CCTCTGTCAAAATTGTTATCAAATCATGAAAACGGATCCAAATAATGCCTTATTTCGTGGCATGACCAATATGAATAATC
AAAACAACCTAGACCCATTTGATGATTTCTTTAGCAATATAGGGAATTTTCAAAATCATCAAGAACCGCAGACTCCTCCT
ACTCAATCAGGTGGTGGATATGGCAATGGAGGCTATGGCTCCAATCAAGGCAATAGTACACGCCAACAAGCACCACAGCA
ACCTAAAGGTCTCCTAGAGGAATTCGGTATCAATGTGACTGAATTTGCTCGGCGTGGTGAAATTGACCCCGTGATTGGTC
GTGATGAGGAAATTGTTCGTGTTATTGAAATCCTCAATCGTAGAACGAAGAACAACCCTGTCCTCATCGGAGAGCCCGGT
GTCGGGAAAACAGCAGTTGTCGAAGGCTTAGCTCAGAAAATTGTAGACGGTGATGTGCCACATAAACTCCAAGGCAAAGA
AGTTATCCGCTTAGATGTCGTTAGCTTGGTTCAAGGAACTGGTATCCGTGGTCAATTTGAAGAACGAATGCAAAAACTCA
TGAACGAAATTCGCTCTCGTCAGGATGTGATATTATTCATTGATGAAATTCACGAAATTGTTGGAGCTGGTTCTGCCGGT
GATGGAAATATGGATGCTGGAAACATTCTAAAACCAGCACTTGCTCGCGGTGAACTCCAATTAGTTGGTGCCACAACTCT
CAATGAATACCGGATTATCGAAAAAGATGCTGCACTGGAACGCCGTATGCAGCCTGTAAAAGTTGATGAACCAACAGTTG
AAGAAACAATCACTATCCTCAAAGGTATTCAAAAGAAATACGAAGACTATCACCACGTCAAATACACCGACGATGCCATT
GAAGCAGCAGCTGTCTTGTCCAATCGTTATATCCAAGATCGCTTCTTGCCTGATAAGGCCATTGACTTGCTAGATGAAGC
AGGCTCTAAGATGAATCTGACACTTAACTTTGTCGATCCAAAAGTCATTGATCAACGATTGGTAGAGGCTGAAAACCTCA
AGGCACAAGCTACTCGTGATGAAGATTTTGAAAAAGCTGCTTATTTCCGTGACCAAATTGCCAAATACAAAGAAATGCAG
CAAAATAAAATGGCTGATCAAGATACGCCTCTTATCAGTGAAAAAACCATTGAACATATCATTGAGCAAAAGACCAATAT
TCCAGTTGGCGACTTGAAAGAAAAGGAACAATCACAATTGATTAGTCTGGCTGATGATTTGAAAACTCATGTCATTGGTC
AAGATGATGCTGTTGATAAAATTGCCAAAGCTATTCGCCGTAATCGAGTTGGACTAGGTACACCAAACCGACCAATTGGT
TCTTTCCTTTTTGTTGGGCCAACCGGTGTCGGCAAAACAGAACTCTCTAAACAATTAGCGATTGAGCTCTTTGGTTCAGC
TGACAGCATGATTCGCTTTGATATGAGTGAGTATATGGAAAAACATAGCGTAGCAAAACTCGTCGGAGCGCCTCCAGGTT
ACGTTGGCTACGAAGAGGCTGGGCAATTAACAGAACGCGTACGTCGTAATCCTTATTCTCTCATTTTACTTGATGAAATA
GAAAAAGCTCACCCAGATGTCATGCACATGTTCTTGCAAGTACTGGATGACGGACGTCTGACAGATGGACAAGGTCGGAC
AGTCAGTTTCAAAGATACGATTATCATTATGACTTCCAACGCCGGTACTGGAAAAGTTGAAGCAAACGTCGGATTCGGTG
CAGCGCGTGAAGGACGAACCAATTCTGTTATCGGTGAATTAGGGAACTTCTTCAGTCCAGAATTTATGAACCGTTTTGAT
GGTATTATTGAGTTCAAATCTCTTAGCAAAGAAAATCTCCTACAAATCGTAGATTTGATGCTTAAAGATGTCAATGAACG
GCTTGCCACGAATGACATTTACCTAGATGTAACAGATAAAGTCAAGGAAAAATTAGTTAATCTTGGTTACGATCCGAAAA
TGGGAGCTCGTCCACTTCGTCGGACAATCCAAGATCACATTGAGGATGCTATCACTGACTACTATCTTGAACATCCAAGC
GACAAAGAGCTCAAAGCTATCATGACAAGTAATGGTAAGATTGTCATCAAACCAGCTAAAAAATCTGAGAATAAATCCAA
TAAAGAAAGCTAG

Domains

Predicted by InterproScan.

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(648-722)

ATPase family associated with various cellular activities (AAA) (AAA)

(154-273)

AAA lid domain (AAA_lid_9)

(292-389)

AAA domain (Cdc48 subfamily) (AAA_2)

(477-640)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpE Streptococcus pneumoniae Rx1

86.551

100

0.867
  clpE Streptococcus pneumoniae D39

86.551

100

0.867
  clpE Streptococcus pneumoniae R6

86.551

100

0.867
  clpE Streptococcus pneumoniae TIGR4

86.551

100

0.867
  clpE Streptococcus mutans UA159

84.615

100

0.851
  clpC Lactococcus lactis subsp. cremoris KW2

78.003

98.8

0.771
  clpC Bacillus subtilis subsp. subtilis str. 168

49.857

93.067

0.464
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

47.546

86.933

0.413
  clpC Streptococcus pneumoniae Rx1

48.47

82.8

0.401
  clpC Streptococcus pneumoniae D39

48.47

82.8

0.401
  clpC Streptococcus pneumoniae TIGR4

48.309

82.8

0.4
  clpC Streptococcus thermophilus LMD-9

47.191

83.067

0.392
  clpC Streptococcus mutans UA159

46.372

84.533

0.392
  clpC Streptococcus thermophilus LMG 18311

47.115

83.2

0.392

Multiple sequence alignment