Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpC   Type   Regulator
Locus tag   A6J72_RS04565 Genome accession   NZ_CP020433
Coordinates   922100..924529 (-) Length   809 a.a.
NCBI ID   WP_082311878.1    Uniprot ID   -
Organism   Streptococcus intermedius strain FDAARGOS_233     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 917100..929529
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A6J72_RS04540 (A6J72_04555) - 917399..918217 (+) 819 WP_082311874.1 hypothetical protein -
  A6J72_RS04545 (A6J72_04560) - 918236..919507 (+) 1272 WP_003077837.1 toxic anion resistance protein -
  A6J72_RS04550 (A6J72_04565) hslO 919716..920588 (+) 873 WP_225791041.1 Hsp33 family molecular chaperone HslO -
  A6J72_RS04555 (A6J72_04570) dusB 920575..921546 (+) 972 WP_082311876.1 tRNA dihydrouridine synthase DusB -
  A6J72_RS04560 (A6J72_04575) - 921617..922057 (-) 441 WP_082311877.1 GNAT family N-acetyltransferase -
  A6J72_RS04565 (A6J72_04580) clpC 922100..924529 (-) 2430 WP_082311878.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  A6J72_RS04570 (A6J72_04585) - 924533..924994 (-) 462 WP_003077510.1 CtsR family transcriptional regulator -
  A6J72_RS04575 (A6J72_04590) - 925253..925603 (+) 351 WP_048785259.1 hypothetical protein -
  A6J72_RS04580 (A6J72_04595) tsf 925680..926723 (-) 1044 WP_003074777.1 translation elongation factor Ts -
  A6J72_RS04585 (A6J72_04600) rpsB 926806..927588 (-) 783 WP_082311879.1 30S ribosomal protein S2 -
  A6J72_RS04595 (A6J72_04610) - 928231..929016 (-) 786 WP_082311880.1 hypothetical protein -

Sequence

Protein


Download         Length: 809 a.a.        Molecular weight: 90060.19 Da        Isoelectric Point: 5.7781

>NTDB_id=222996 A6J72_RS04565 WP_082311878.1 922100..924529(-) (clpC) [Streptococcus intermedius strain FDAARGOS_233]
MKYSKALTESIESAQLLASHFETDYLESWQLLIAMANNPYSVAGSVLNDYPLEIDDFEKAAFHITGKVYQQEGDFTIWPF
SYRMKVLFLTAEQIAGAVHANNLGTEHILLAMLFDQGSLAARILEFIGFSYEDKEGVLRMTDLRKNLEHKASWNKEDLKA
IRHLNKSAAATRQTMANMMGMPPATNGGLEDYTRDLTEMAHMGLLEPVIGRDKEISRILQILSRKTKNNPVLVGDAGVGK
TALALGLAQRVADGQVPNELAKMRVLELDLMNVVAGTRFRGDFEERMNNIINDIEADGHVILFIDELHTIMGSGSGIDST
LDAANILKPALAKGTLRTIGATTQEEYQKYIEKDAALSRRFAKVTIEEPTVADSIAILQGLKKSYEDHHKVVITDSAIEM
AVKYAHRYLTSKHLPDSAIDLLDEAAARVQNKSPQNHVKAELSAADEALMAGDWNKVDTLLEKESQPIVYKLRVKDEDVL
ATLSSLSGIPVQKLTQTDAKKYLNLEKELHKRVIGQNEAISAISRAIRRNQSGIRTSKRPIGSFMFLGPTGVGKTELAKA
LAEVLFDDETALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNRPYSVLLFDEVEKAHPDIFNVLLQVLDDG
VLTDSKGRKVDFSNTIIIMTSNLGATSLRDDKTVGFGARDARFDHESMEKRMMEELKKSYRPEFINRIDEKVVFHSLTSE
DMQEVVKIMVKPLIVSLAEKGIELKFQPSALKLLAQEGYDPEMGARPLRRTLQTQVEDHLSELLLAGELQTGQSLKVGVK
AGKLKFEVL

Nucleotide


Download         Length: 2430 bp        

>NTDB_id=222996 A6J72_RS04565 WP_082311878.1 922100..924529(-) (clpC) [Streptococcus intermedius strain FDAARGOS_233]
ATGAAATATTCAAAAGCTTTGACAGAAAGTATTGAATCAGCACAGTTATTAGCAAGTCATTTTGAAACGGATTATTTAGA
GTCTTGGCAGCTGTTGATTGCTATGGCAAATAATCCTTATAGTGTTGCTGGTTCAGTTTTAAATGATTACCCACTTGAAA
TTGATGATTTTGAAAAGGCAGCTTTTCATATCACGGGGAAAGTCTATCAACAAGAGGGAGACTTTACTATTTGGCCGTTT
TCTTATCGCATGAAAGTGCTATTTTTGACTGCTGAACAAATTGCAGGGGCGGTTCATGCTAATAATCTTGGGACAGAGCA
TATATTGCTAGCTATGTTATTTGACCAAGGAAGCTTGGCAGCGCGTATTCTTGAATTTATTGGTTTTAGTTACGAAGATA
AAGAAGGCGTTTTGCGCATGACAGATCTGCGGAAAAATTTAGAGCATAAGGCCAGCTGGAATAAAGAGGATTTAAAGGCT
ATTCGTCACCTAAATAAAAGTGCTGCAGCAACAAGACAAACGATGGCTAATATGATGGGAATGCCTCCTGCAACCAATGG
CGGACTAGAAGATTATACTCGTGATCTAACTGAAATGGCTCATATGGGCCTTTTAGAACCGGTCATTGGGCGGGATAAAG
AGATTTCTCGCATACTTCAGATTTTAAGTCGTAAGACAAAAAACAATCCGGTTTTGGTAGGAGATGCAGGAGTTGGGAAG
ACAGCATTAGCTCTGGGTTTGGCGCAACGTGTGGCAGATGGTCAAGTTCCAAATGAGCTTGCAAAGATGAGAGTTTTAGA
GCTAGATTTAATGAATGTGGTGGCTGGAACTCGTTTTCGTGGTGATTTTGAAGAACGGATGAACAATATTATCAATGATA
TTGAAGCAGATGGGCATGTTATTCTCTTCATTGATGAGCTTCATACCATTATGGGTTCTGGCAGCGGGATTGACTCGACA
TTAGATGCAGCAAATATTCTCAAGCCGGCTTTGGCTAAAGGAACGCTCAGAACGATCGGTGCAACAACACAAGAAGAGTA
CCAAAAATATATCGAAAAAGATGCAGCTCTTTCACGAAGATTTGCCAAGGTTACTATTGAAGAACCAACGGTAGCTGACA
GCATTGCTATTTTACAGGGACTCAAGAAAAGTTATGAAGATCACCACAAAGTCGTGATTACGGATTCGGCAATTGAGATG
GCTGTTAAGTATGCGCATCGTTACCTGACTAGTAAACATCTACCTGACTCAGCGATTGACTTGCTAGACGAAGCTGCTGC
AAGGGTACAAAATAAAAGCCCGCAAAATCACGTAAAAGCAGAATTGAGTGCAGCAGATGAGGCTTTAATGGCAGGCGATT
GGAACAAAGTTGATACGTTGTTGGAGAAAGAGAGTCAGCCAATTGTTTATAAATTAAGAGTGAAAGACGAGGATGTTTTA
GCAACACTCAGCAGTTTATCAGGTATTCCTGTGCAAAAGTTGACACAAACAGATGCGAAGAAATACCTCAATTTAGAAAA
GGAGTTACACAAACGAGTTATCGGGCAGAATGAAGCAATTTCTGCTATTAGTCGAGCGATTCGGCGCAATCAATCTGGTA
TCCGCACTAGCAAGCGCCCAATTGGCTCCTTTATGTTCTTAGGGCCAACCGGGGTCGGAAAAACTGAGCTAGCTAAGGCT
TTGGCAGAAGTTCTCTTTGATGACGAAACAGCGTTAATTCGTTTTGATATGTCCGAATACATGGAGAAATTTGCTGCTAG
TCGTCTCAATGGAGCGCCTCCAGGTTATGTCGGTTATGAAGAAGGGGGCGAATTGACTGAAAAAGTTCGCAATCGTCCTT
ACTCTGTGCTCCTTTTTGACGAGGTGGAAAAAGCTCACCCTGATATTTTCAATGTGCTTCTCCAAGTCTTAGATGACGGG
GTGCTGACCGACAGCAAGGGACGCAAGGTGGATTTTTCCAATACCATTATCATTATGACCAGCAATCTTGGTGCGACAAG
TTTGCGGGATGATAAGACGGTCGGTTTTGGAGCGCGTGATGCCCGCTTTGATCATGAAAGCATGGAAAAACGGATGATGG
AAGAACTCAAGAAAAGTTATCGTCCGGAATTTATCAACCGGATTGATGAAAAGGTTGTTTTCCATAGCCTGACTAGCGAA
GACATGCAAGAAGTGGTAAAAATTATGGTGAAGCCACTCATTGTCAGTCTCGCTGAAAAAGGAATTGAGCTGAAATTCCA
ACCTAGTGCTTTGAAGCTTCTAGCTCAAGAGGGCTATGATCCTGAAATGGGAGCAAGACCACTTCGCAGAACTCTACAAA
CTCAGGTAGAAGATCATTTATCCGAATTACTTTTAGCTGGTGAGTTACAGACGGGACAAAGTTTGAAAGTCGGTGTCAAA
GCTGGAAAGCTGAAGTTTGAAGTGCTATGA

Domains

Predicted by InterproScan.

AAA lid domain (AAA_lid_9)

(371-446)

AAA domain (Cdc48 subfamily) (AAA_2)

(539-710)

ATPase family associated with various cellular activities (AAA) (AAA)

(231-349)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(717-797)

Clp amino terminal domain, pathogenicity island component (Clp_N)

(14-60)

Clp amino terminal domain, pathogenicity island component (Clp_N)

(91-133)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpC Streptococcus pneumoniae TIGR4

76.819

100

0.77
  clpC Streptococcus pneumoniae Rx1

76.819

100

0.77
  clpC Streptococcus pneumoniae D39

76.819

100

0.77
  clpC Streptococcus mutans UA159

66.626

100

0.671
  clpC Streptococcus thermophilus LMG 18311

65.479

100

0.659
  clpC Streptococcus thermophilus LMD-9

65.356

100

0.658
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

49.519

100

0.509
  clpC Bacillus subtilis subsp. subtilis str. 168

45.761

99.135

0.454

Multiple sequence alignment