Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP   Type   Regulator
Locus tag   A6J72_RS03195 Genome accession   NZ_CP020433
Coordinates   645878..647752 (-) Length   624 a.a.
NCBI ID   WP_003073669.1    Uniprot ID   A0A3R9JBZ9
Organism   Streptococcus intermedius strain FDAARGOS_233     
Function   require for competence development; phosphorylate ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 640878..652752
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A6J72_RS03165 (A6J72_03160) - 641020..641337 (+) 318 WP_009568141.1 DUF960 domain-containing protein -
  A6J72_RS03170 (A6J72_03165) - 641457..641849 (-) 393 WP_014829583.1 S1 RNA-binding domain-containing protein -
  A6J72_RS03175 (A6J72_03170) - 641851..643251 (-) 1401 WP_102570638.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  A6J72_RS03180 (A6J72_03175) - 643291..643923 (-) 633 WP_082311762.1 response regulator transcription factor -
  A6J72_RS03185 (A6J72_03180) - 643925..644920 (-) 996 WP_082311763.1 sensor histidine kinase -
  A6J72_RS03190 (A6J72_03185) liaF 644917..645615 (-) 699 WP_082311764.1 cell wall-active antibiotics response protein LiaF -
  A6J72_RS03195 (A6J72_03190) stkP 645878..647752 (-) 1875 WP_003073669.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  A6J72_RS03200 (A6J72_03195) - 647749..648489 (-) 741 WP_003073671.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  A6J72_RS03205 (A6J72_03200) rsmB 648508..649821 (-) 1314 WP_082311765.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  A6J72_RS03210 (A6J72_03205) fmt 649811..650746 (-) 936 WP_082311766.1 methionyl-tRNA formyltransferase -

Sequence

Protein


Download         Length: 624 a.a.        Molecular weight: 67672.81 Da        Isoelectric Point: 9.6670

>NTDB_id=222990 A6J72_RS03195 WP_003073669.1 645878..647752(-) (stkP) [Streptococcus intermedius strain FDAARGOS_233]
MIQVGKIFAGRYRIIKQIGRGGMADVYLAKDLILDGEEVAVKVLRTNYQTDPIAVARFQREARAMADLDHPHIVRITDIG
EEEGQQYLAMEYVAGLDLKRYIKEHAPLSNEEAVRIMGQILLAMRLAHTHGIVHRDLKPQNVLLTPDGDAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAVTIALQHFQKPLPSVIAENPNVP
QALENVVIKATAKKLTDRYQSVAEMYVDLSSCLSADRRNEKKLVFDDTVKADTKTLPKVSQNTLTSASKPTATSTKEAVD
NQTKPKPKPKKKRRLRTRYKVLLSAVVLVIAALVALVYLSPSNVKIPDVTGKTVAQARSAIEAAGLKVGKEKDEYSDSAK
KDSVIRTNPQAGTQRREGSTVDLIVSKGPKTFTMEDYSGQKKADAINSLVQKYKVSKGLIKIEEVESSDYAAGTVVSQTP
AAGSTYDLTSKNRITLKVAKTVSSVTMPSYIGSTYEFAYNNLTEVIGVQGANVEKRIVTTAPAGTQAHTIIKQSPEAKRP
LNLKNDRIVLYVYEPKTEESSTSESSSQSGSSSNKNSPSSSSSSSSGNDGSSSKTPDTSASASN

Nucleotide


Download         Length: 1875 bp        

>NTDB_id=222990 A6J72_RS03195 WP_003073669.1 645878..647752(-) (stkP) [Streptococcus intermedius strain FDAARGOS_233]
ATGATTCAAGTCGGCAAAATATTTGCCGGACGATATAGAATCATCAAACAAATCGGTCGAGGAGGCATGGCAGATGTTTA
CTTGGCGAAAGATTTGATTTTAGACGGGGAAGAAGTCGCAGTTAAGGTTCTAAGAACCAACTACCAGACAGATCCGATTG
CTGTAGCGCGTTTTCAAAGAGAGGCGCGAGCCATGGCAGATTTGGATCATCCTCATATTGTCCGGATTACCGACATTGGA
GAAGAAGAAGGCCAGCAATATCTAGCAATGGAGTATGTGGCTGGACTTGACTTGAAACGCTATATCAAAGAGCATGCTCC
TTTGTCCAATGAAGAAGCGGTGCGAATCATGGGACAAATCCTTTTGGCGATGCGTTTGGCGCATACGCATGGGATTGTTC
ACCGTGATTTAAAACCTCAAAATGTCCTTTTAACTCCAGATGGCGATGCAAAAGTAACTGACTTTGGAATTGCAGTAGCT
TTTGCAGAAACGAGTTTAACCCAGACAAATTCAATGCTGGGATCTGTACATTATCTATCACCAGAACAGGCACGTGGGTC
AAAAGCAACAGTTCAAAGTGATATTTATGCTATGGGGATTATTTTCTATGAAATGCTGACAGGTCACATTCCTTATGATG
GGGATAGTGCTGTGACGATTGCACTGCAGCATTTCCAAAAACCCCTTCCTTCTGTAATTGCTGAAAATCCAAATGTTCCA
CAAGCATTAGAAAATGTGGTTATCAAGGCAACGGCAAAAAAATTAACAGATCGTTATCAATCTGTTGCAGAAATGTATGT
TGACTTATCTAGTTGTTTATCTGCTGATCGTCGAAATGAGAAGAAATTAGTTTTTGATGATACTGTTAAAGCAGACACTA
AGACGCTTCCTAAAGTATCACAGAATACGTTGACTTCAGCGTCTAAACCGACTGCTACATCTACAAAAGAAGCTGTTGAT
AATCAAACTAAGCCTAAACCAAAACCAAAGAAAAAACGTCGTTTAAGAACACGTTATAAAGTGTTGTTGTCGGCAGTAGT
CTTAGTTATTGCAGCTTTGGTGGCTTTAGTCTATTTGAGTCCCTCAAATGTAAAAATACCAGATGTTACTGGAAAAACCG
TTGCGCAAGCACGTTCCGCGATTGAAGCTGCAGGTTTGAAAGTTGGCAAGGAGAAAGACGAATACAGTGATTCTGCTAAG
AAAGATTCTGTCATTCGTACGAATCCACAAGCGGGAACACAACGTCGCGAAGGAAGCACAGTAGATTTGATTGTCTCAAA
AGGGCCGAAAACATTTACTATGGAAGATTATAGCGGTCAGAAAAAAGCAGATGCTATCAACAGTTTGGTGCAAAAATACA
AAGTTTCAAAGGGCTTGATTAAAATTGAAGAAGTCGAAAGTAGTGACTATGCAGCAGGAACTGTTGTTAGTCAGACGCCG
GCAGCAGGTAGTACGTATGATTTGACTTCAAAAAATCGGATTACGTTAAAAGTAGCGAAGACGGTTTCAAGTGTTACAAT
GCCAAGTTATATAGGTTCCACTTATGAATTTGCCTATAATAACCTTACCGAAGTTATTGGCGTTCAAGGAGCTAATGTTG
AAAAACGAATAGTTACAACAGCTCCAGCAGGAACACAGGCACACACGATTATTAAACAAAGCCCAGAAGCAAAGAGGCCT
CTAAATTTAAAAAATGATCGTATTGTCTTATATGTATATGAGCCAAAAACTGAAGAATCATCTACATCTGAAAGTAGTTC
GCAATCTGGAAGCAGTTCAAATAAAAATAGTCCATCATCTAGTAGTTCGTCGAGTAGCGGTAATGATGGATCAAGTTCGA
AAACACCAGACACAAGCGCTAGTGCAAGTAATTAA

Domains

Predicted by InterproScan.

Protein kinase domain (Pkinase)

(12-227)

PASTA domain (PASTA)

(433-500)

PASTA domain (PASTA)

(505-573)

PASTA domain (PASTA)

(364-427)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A3R9JBZ9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP Streptococcus pneumoniae TIGR4

66.381

93.429

0.62
  stkP Streptococcus pneumoniae D39

66.038

93.429

0.617
  stkP Streptococcus pneumoniae R6

66.038

93.429

0.617
  stkP Streptococcus pneumoniae Rx1

65.866

93.429

0.615
  pknB Streptococcus mutans UA159

59.658

93.75

0.559
  stkP/pknB Streptococcus salivarius strain HSISS4

59.294

86.218

0.511

Multiple sequence alignment