Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   SAG_RS13390 Genome accession   NC_004116
Coordinates   2158070..2159299 (+) Length   409 a.a.
NCBI ID   WP_000728358.1    Uniprot ID   A0AAW3HT93
Organism   Streptococcus agalactiae 2603V/R     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2153070..2164299
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SAG_RS13365 (SAG2172) - 2154232..2156811 (+) 2580 WP_000154437.1 YfhO family protein -
  SAG_RS13385 (SAG2173) rlmH 2157390..2157869 (-) 480 WP_000768335.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  SAG_RS13390 (SAG2174) htrA 2158070..2159299 (+) 1230 WP_000728358.1 S1C family serine protease Regulator
  SAG_RS13395 (SAG2175) spo0J 2159397..2160170 (+) 774 WP_000456087.1 ParB/RepB/Spo0J family partition protein Regulator

Sequence

Protein


Download         Length: 409 a.a.        Molecular weight: 43118.59 Da        Isoelectric Point: 9.5271

>NTDB_id=22293 SAG_RS13390 WP_000728358.1 2158070..2159299(+) (htrA) [Streptococcus agalactiae 2603V/R]
MKKKLVSSLLKCSLIIIVSFAGGAFASFVMNHNDNIPNGGVTKTSKVNYNNITPTTKAVKKVQNSVVSVINYKQQESRSD
LSDFYSHFFGNQGGNTDKGLQVYGEGSGVIYKKDGKNAYVVTNNHVIDGAKQIEIQLADGSKAVGKLVGSDTYSDLAVVK
IPSDKVSNIAEFADSSKLNIGETAIAIGSPLGTEYANSVTQGIVSSLKRTVTMTNEEGQTVSTNAIQTDAAINPGNSGGA
LINIEGQVIGINSSKISSTSNQTSGQSSGNSVEGMGFAIPSNDVVKIINQLESNGQVERPALGISMAGLSNLPSDVISKL
KIPSNVTNGIVVASIQSGMPAQGKLKKYDVITKVDDKEVVSPSDLQSLLYGHQVGDSITVTFYRGENKQTVTIKLTKTSK
DLAKQRANN

Nucleotide


Download         Length: 1230 bp        

>NTDB_id=22293 SAG_RS13390 WP_000728358.1 2158070..2159299(+) (htrA) [Streptococcus agalactiae 2603V/R]
GTGAAAAAAAAATTAGTCTCATCACTTCTAAAGTGTTCTCTAATCATTATTGTTAGCTTTGCTGGTGGAGCATTTGCTAG
TTTTGTCATGAATCATAATGACAATATTCCAAATGGTGGTGTCACTAAAACTAGTAAAGTAAATTATAATAACATAACGC
CTACAACAAAAGCTGTTAAAAAGGTACAAAATAGTGTTGTTTCTGTTATCAATTATAAACAACAAGAGAGTCGTTCTGAC
CTATCAGACTTCTATAGTCATTTTTTTGGTAATCAGGGGGGCAACACTGATAAGGGCTTACAAGTTTACGGTGAAGGCTC
TGGAGTCATCTATAAAAAAGATGGTAAAAATGCCTATGTTGTCACTAATAACCACGTCATTGATGGGGCTAAACAAATTG
AAATTCAACTAGCTGATGGCTCAAAAGCAGTTGGGAAACTTGTTGGGTCAGATACCTACTCTGATTTAGCCGTCGTCAAA
ATTCCATCAGATAAGGTTTCAAATATTGCAGAATTTGCTGATTCATCAAAACTCAACATTGGTGAAACTGCTATAGCGAT
CGGAAGCCCTCTTGGAACTGAGTATGCAAATTCTGTAACTCAAGGTATTGTATCTAGTTTAAAAAGAACTGTAACAATGA
CTAATGAAGAAGGACAAACAGTTTCTACAAATGCTATCCAGACTGATGCTGCTATCAATCCTGGTAATTCAGGTGGAGCA
CTTATCAATATTGAAGGACAGGTTATTGGAATTAATTCTAGTAAAATTTCTTCTACATCAAATCAAACCTCAGGACAATC
GTCAGGAAATAGCGTTGAAGGTATGGGATTTGCCATTCCTTCAAATGATGTTGTTAAGATTATCAATCAACTTGAGAGTA
ACGGACAAGTAGAGAGACCTGCTCTAGGTATTTCTATGGCTGGATTAAGTAATTTACCATCCGATGTTATTAGTAAACTG
AAAATCCCAAGTAATGTTACTAATGGTATTGTAGTAGCATCTATCCAATCTGGCATGCCAGCTCAAGGCAAACTAAAGAA
ATACGATGTCATTACTAAAGTTGACGATAAAGAAGTAGTATCTCCAAGTGATTTACAAAGTTTACTCTATGGCCACCAGG
TAGGGGATTCCATAACAGTAACCTTTTATCGTGGTGAAAATAAACAAACAGTCACTATAAAACTTACTAAAACTAGTAAA
GATTTAGCTAAACAACGAGCAAATAACTAA

Domains

Predicted by InterproScan.

Trypsin-like peptidase domain (Trypsin_2)

(106-251)

PDZ domain (PDZ_2)

(300-395)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

63.104

96.088

0.606
  htrA Streptococcus gordonii str. Challis substr. CH1

57.357

98.044

0.562
  htrA Streptococcus mitis NCTC 12261

56.281

97.311

0.548
  htrA Streptococcus pneumoniae TIGR4

54.791

99.511

0.545
  htrA Streptococcus pneumoniae Rx1

54.791

99.511

0.545
  htrA Streptococcus pneumoniae D39

54.791

99.511

0.545
  htrA Streptococcus pneumoniae R6

54.791

99.511

0.545

Multiple sequence alignment