Detailed information NTG0222689

Bioinformatically predicted

Overview

• Name: pilA
• Type: Machinery gene
• Locus tag: A6J49_RS13200
• Genome accession: NZ_CP020421
• Coordinates: 2249659..2250924 (-)
• Length: 421 a.a.
• NCBI ID: WP_002243928.1
• Uniprot ID: P57011
• Organism: Neisseria meningitidis strain FDAARGOS_210
• Function: assembly of type IV pilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2244659..2255924

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A6J49_RS13180 (A6J49_12745)	-	2248747..2249031 (-)	285	WP_002216166.1	GIY-YIG nuclease family protein	-
A6J49_RS13200 (A6J49_12760)	pilA	2249659..2250924 (-)	1266	WP_002243928.1	signal recognition particle-docking protein FtsY	Machinery gene
A6J49_RS13210 (A6J49_12770)	msrAB	2251070..2252638 (+)	1569	WP_010980745.1	bifunctional peptide-methionine (S)-S-oxide reductase MsrA/peptide-methionine (R)-S-oxide reductase MsrB	-
A6J49_RS13215 (A6J49_12775)	-	2252740..2253225 (-)	486	WP_002215245.1	CinA family protein	-
A6J49_RS13220 (A6J49_12780)	-	2253251..2254099 (-)	849	WP_002215243.1	mechanosensitive ion channel family protein	-
A6J49_RS13225 (A6J49_12785)	-	2254193..2255194 (-)	1002	WP_002243927.1	thiamine ABC transporter substrate-binding protein	-

Sequence

Protein

• Length: 421 a.a.
• Molecular weight: 45143.47 Da
• Isoelectric Point: 4.5557

>NTDB_id=222689 A6J49_RS13200 WP_002243928.1 2249659..2250924(-) (pilA) [Neisseria meningitidis strain FDAARGOS_210]
MFSFFRRKKKQETPALEEAQIQETAAKAESELAQIVENIKEDAESLAESVKGQVESAVETVSGAVEQVKETVAEMLSEAE
EAAEKAAEQVEAAKEAVAETVGEAVGQVQEAVATTEEHKLGWAARLKQGLTKSRDKMAKSLAGVFGGGQIDEDLYEELET
VLITSDMGMEATEYLMKDVRDRVSLKGLKDGNELRGALKEALYDLIKPLEKPLVLPETKEPFVIMLAGINGAGKTTSIGK
LAKYFQAQGKSVLLAAGDTFRAAAREQLQAWGERNNVTVISQTTGDSAAVCFDAVQAAKARGIDIVLADTAGRLPTQLHL
MEEIKKVKRVLQKAMPDAPHEIIVVLDANIGQNAVNQVKAFDDALGLTGLIVTKLDGTAKGGILAALASDRPVPVRYIGV
GEGIDDLRPFDARAFVDALLD

Nucleotide

• Length: 1266 bp

>NTDB_id=222689 A6J49_RS13200 WP_002243928.1 2249659..2250924(-) (pilA) [Neisseria meningitidis strain FDAARGOS_210]
ATGTTCAGCTTCTTCCGTCGCAAGAAAAAACAGGAAACGCCGGCTCTCGAGGAGGCTCAAATTCAGGAAACCGCAGCAAA
AGCAGAATCTGAACTTGCTCAAATAGTTGAAAATATTAAAGAAGATGCTGAATCTTTAGCAGAAAGCGTCAAAGGGCAGG
TCGAATCTGCCGTTGAAACCGTCAGCGGTGCGGTTGAACAGGTAAAGGAAACCGTTGCCGAGATGCTGTCTGAAGCAGAG
GAAGCGGCGGAAAAAGCAGCGGAACAAGTCGAAGCGGCAAAAGAAGCCGTTGCCGAAACCGTCGGCGAGGCTGTCGGGCA
AGTTCAAGAAGCCGTTGCGACAACTGAAGAACACAAGCTCGGTTGGGCGGCGCGTTTGAAACAAGGCCTGACCAAATCGC
GCGACAAAATGGCGAAATCGCTGGCGGGCGTGTTCGGCGGCGGACAAATCGACGAAGATTTATACGAAGAGCTGGAAACC
GTGCTGATTACCAGCGATATGGGCATGGAAGCCACCGAATACCTGATGAAAGACGTGCGCGACCGCGTCAGCCTCAAAGG
GCTGAAAGACGGCAACGAATTGCGCGGCGCGTTGAAAGAAGCCTTGTACGACCTGATTAAGCCTCTGGAGAAACCTTTGG
TTTTGCCCGAAACCAAAGAGCCGTTTGTCATCATGCTTGCCGGCATCAACGGCGCGGGCAAAACCACGTCTATCGGTAAA
CTCGCCAAATATTTCCAAGCGCAGGGCAAATCCGTATTGCTGGCGGCAGGCGATACTTTCCGTGCCGCCGCGCGTGAGCA
GCTTCAAGCTTGGGGCGAGCGCAACAACGTAACCGTGATTTCGCAAACCACGGGCGATTCCGCCGCCGTGTGCTTCGATG
CCGTCCAAGCCGCCAAAGCGCGCGGCATCGACATTGTGCTGGCCGACACCGCCGGCCGCCTGCCCACGCAGCTTCATTTG
ATGGAAGAAATCAAAAAAGTGAAACGCGTGCTGCAAAAAGCCATGCCCGACGCGCCGCACGAAATCATCGTCGTGCTTGA
TGCCAATATCGGGCAAAACGCCGTCAACCAAGTCAAAGCCTTTGACGACGCATTGGGGCTGACCGGTTTAATCGTTACCA
AACTCGACGGCACGGCAAAAGGCGGCATCCTCGCCGCGCTTGCCTCCGACCGCCCCGTTCCCGTCCGCTATATCGGCGTG
GGCGAAGGCATAGACGACCTGCGCCCGTTTGACGCGCGCGCGTTTGTGGACGCACTGCTGGATTGA

Domains

Predicted by InterproScan.

• SRP54-type protein, GTPase domain (SRP54) (221-420)

• SRP54-type protein, helical bundle domain (SRP54_N) (136-202)

3D structure

• AlphaFold DB: P57011

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilA	Neisseria gonorrhoeae MS11	94.774	100	0.948