Detailed information NTG0222682

Bioinformatically predicted

Overview

• Name: pilD
• Type: Machinery gene
• Locus tag: A6J49_RS11440
• Genome accession: NZ_CP020421
• Coordinates: 1953136..1953996 (+)
• Length: 286 a.a.
• NCBI ID: WP_002212335.1
• Uniprot ID: Q9K154
• Organism: Neisseria meningitidis strain FDAARGOS_210
• Function: assembly of type IV pilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1948136..1958996

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A6J49_RS11420 (A6J49_11025)	dapD	1948799..1949620 (-)	822	WP_002224875.1	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase	-
A6J49_RS11425 (A6J49_11030)	-	1949630..1949860 (-)	231	WP_009348191.1	hypothetical protein	-
A6J49_RS11430 (A6J49_11035)	pgi	1949830..1951473 (-)	1644	WP_002224874.1	glucose-6-phosphate isomerase	-
A6J49_RS11435 (A6J49_11040)	pilG	1951830..1953062 (+)	1233	WP_002216405.1	type 4 pilus assembly protein PilG	Machinery gene
A6J49_RS11440 (A6J49_11045)	pilD	1953136..1953996 (+)	861	WP_002212335.1	A24 family peptidase	Machinery gene
A6J49_RS11445 (A6J49_11050)	coaE	1953998..1954630 (+)	633	WP_002224873.1	dephospho-CoA kinase	-
A6J49_RS11450 (A6J49_11055)	-	1954623..1954832 (+)	210	WP_002224872.1	DNA gyrase inhibitor YacG	-
A6J49_RS11455 (A6J49_11060)	pilF	1954917..1956593 (-)	1677	WP_002221967.1	type IV-A pilus assembly ATPase PilB	Machinery gene
A6J49_RS11470 (A6J49_11070)	-	1957035..1957481 (-)	447	WP_002216397.1	DUF441 domain-containing protein	-
A6J49_RS11475 (A6J49_11075)	ispB	1957486..1958460 (-)	975	WP_002216396.1	octaprenyl diphosphate synthase	-
A6J49_RS11485 (A6J49_11085)	rplU	1958684..1958992 (+)	309	WP_002216394.1	50S ribosomal protein L21	-

Sequence

Protein

• Length: 286 a.a.
• Molecular weight: 31305.31 Da
• Isoelectric Point: 8.4690

>NTDB_id=222682 A6J49_RS11440 WP_002212335.1 1953136..1953996(+) (pilD) [Neisseria meningitidis strain FDAARGOS_210]
MSDLSVLSPFAVPLAAVFGLLVGSFLNVVIYRVPVMMERGWTVFAKEYLNLPLTEEESRTFNLMKPDSCCPKCRVPIRAW
QNIPIVSYLLLRGKCASCQTKISIRYPLIELLTGVLFGLVAWQYGWSWITLGGLVLTAFLISLTFIDADTQYLPDSMTLP
LIWLGLIFNLDGGFVPLQSAVLGAVAGYGSLWLLCAVYKLLTGKTGMGNGDFKLIAALGAWLGISALPVLIFVSSLIGLV
AAIVMRVAKGQHFAFGPALTVSGWIIFTANDSVWRAVNWWLTHPVL

Nucleotide

• Length: 861 bp

>NTDB_id=222682 A6J49_RS11440 WP_002212335.1 1953136..1953996(+) (pilD) [Neisseria meningitidis strain FDAARGOS_210]
ATGTCTGATTTGTCTGTATTGTCGCCGTTTGCCGTGCCTTTGGCAGCGGTGTTCGGGCTGCTGGTCGGAAGTTTCTTAAA
TGTCGTCATTTACCGCGTGCCGGTCATGATGGAACGCGGCTGGACGGTATTTGCCAAAGAATATTTAAACCTGCCGCTGA
CCGAAGAGGAAAGCCGTACCTTCAACCTGATGAAACCGGATTCCTGCTGTCCCAAATGCCGCGTGCCGATACGCGCGTGG
CAGAACATCCCGATTGTCAGCTACCTGCTCCTGCGCGGCAAATGCGCTTCCTGCCAAACCAAAATCAGCATACGTTATCC
CTTAATCGAGCTGCTGACCGGCGTATTGTTCGGGCTGGTCGCCTGGCAATACGGCTGGTCTTGGATTACGCTGGGCGGAT
TGGTACTGACCGCGTTTCTGATTTCCCTGACCTTTATCGATGCGGACACCCAATACCTGCCCGACTCGATGACACTGCCC
TTAATTTGGCTGGGTCTGATATTTAATTTGGACGGCGGCTTCGTGCCTTTGCAGTCTGCCGTTTTAGGTGCGGTCGCCGG
CTATGGTTCATTATGGCTCTTATGTGCAGTGTATAAACTGCTCACAGGAAAAACCGGTATGGGCAACGGAGATTTCAAAC
TGATTGCCGCATTGGGCGCGTGGCTCGGCATATCCGCATTGCCCGTACTGATTTTTGTTTCCTCGCTGATCGGTTTGGTC
GCGGCAATCGTTATGCGCGTCGCCAAGGGGCAGCATTTTGCCTTCGGCCCCGCACTGACAGTTTCGGGCTGGATAATTTT
TACGGCAAACGATTCCGTATGGCGGGCGGTCAACTGGTGGCTGACCCATCCGGTGCTGTAA

Domains

Predicted by InterproScan.

• Bacterial Peptidase A24 N-terminal domain (A24_N_bact) (17-124)

• Type IV leader peptidase family (Peptidase_A24) (134-242)

3D structure

• AlphaFold DB: Q9K154

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilD	Neisseria gonorrhoeae MS11	97.544	99.65	0.972
pilD	Vibrio cholerae strain A1552	45.833	100	0.462
pilD	Vibrio campbellii strain DS40M4	46.377	96.503	0.448
pilD	Acinetobacter baumannii D1279779	48.106	92.308	0.444
pilD	Acinetobacter nosocomialis M2	48.106	92.308	0.444