Detailed information NTG0022262

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: SAG_RS05105
• Genome accession: NC_004116
• Coordinates: 468959..470032 (+)
• Length: 357 a.a.
• NCBI ID: WP_000796095.1
• Uniprot ID: A0A0E1EG10
• Organism: Streptococcus agalactiae 2603V/R
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 463959..475032

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SAG_RS05075 (SAG0449)	-	464852..465916 (+)	1065	WP_000021302.1	MmcQ/YjbR family DNA-binding protein	-
SAG_RS05080 (SAG0450)	asnA	466030..467022 (+)	993	WP_000748011.1	aspartate--ammonia ligase	-
SAG_RS05085 (SAG0451)	-	467067..467516 (-)	450	WP_000592263.1	thiol reductase thioredoxin	-
SAG_RS05090 (SAG0452)	rsmD	467646..468185 (+)	540	WP_001266829.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
SAG_RS05095 (SAG0453)	-	468197..468487 (+)	291	WP_000384889.1	hypothetical protein	-
SAG_RS05100 (SAG0454)	coaD	468484..468969 (+)	486	WP_000161892.1	pantetheine-phosphate adenylyltransferase	-
SAG_RS05105 (SAG0455)	sepM	468959..470032 (+)	1074	WP_000796095.1	SepM family pheromone-processing serine protease	Regulator
SAG_RS05110 (SAG0456)	-	470107..471439 (+)	1333	Protein_444	bifunctional metallophosphatase/5'-nucleotidase	-
SAG_RS05115 (SAG0457)	-	471508..472086 (+)	579	WP_001224500.1	YutD family protein	-
SAG_RS05120 (SAG0458)	rlmN	472137..473243 (+)	1107	WP_001124990.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
SAG_RS05125 (SAG0459)	-	473243..473758 (+)	516	WP_000919802.1	VanZ family protein	-

Sequence

Protein

• Length: 357 a.a.
• Molecular weight: 39199.43 Da
• Isoelectric Point: 10.4385

>NTDB_id=22262 SAG_RS05105 WP_000796095.1 468959..470032(+) (sepM) [Streptococcus agalactiae 2603V/R]
MKNRDPKRKHKSLLGLLKWWIIGFAFLLLVLASLVVRLPYYLEMPGGAYDIRSVLKVNKKADKAKGSYNFVAVSVSQATP
AQVLYAWLTPFTELSSKEETTGGFSNDDYLRINQFYMETSQNESIYQALKLANKQVSLTYKGVYVLNLAKNSTFKDRLHL
ADTVTGVNGKSFKNSSQLIKYVAALHLGDKVKVQYTSQGKKKESVGKVIKLSNGKNGIGIGLTDHTEVLSDVPVDFNTEG
VGGPSAGLMFTLAIYDQLVKEDLRKGRKIAGTGTIEQNGHVGDIGGAGLKVVSAAKKGMDIFFVPNNPIDKNAKKGKTKV
QTNYQEAKAAAKRLGTKMKIVPVQNVQQAIDYLKKTK

Nucleotide

• Length: 1074 bp

>NTDB_id=22262 SAG_RS05105 WP_000796095.1 468959..470032(+) (sepM) [Streptococcus agalactiae 2603V/R]
GTGAAGAATAGAGATCCAAAAAGAAAACATAAAAGTTTACTAGGTCTGCTTAAATGGTGGATTATAGGTTTTGCTTTTTT
ATTGTTAGTATTAGCAAGCCTTGTAGTGAGACTACCTTATTATTTGGAAATGCCAGGTGGAGCTTATGATATCCGTTCGG
TATTGAAAGTGAATAAAAAGGCTGATAAAGCTAAGGGTTCGTACAATTTTGTAGCGGTATCTGTCAGTCAAGCAACGCCA
GCTCAGGTTCTTTATGCTTGGTTAACTCCTTTTACAGAATTATCTAGTAAAGAGGAGACAACAGGTGGCTTTAGTAATGA
CGATTATCTCAGAATTAATCAATTCTACATGGAGACTTCTCAAAATGAGTCCATCTATCAAGCTTTAAAGTTAGCTAATA
AGCAAGTATCTCTTACTTATAAAGGAGTTTATGTGCTTAACTTAGCTAAAAATTCGACATTTAAAGATAGATTACATTTA
GCTGATACAGTCACAGGAGTTAATGGCAAAAGTTTCAAAAATTCTTCTCAACTTATCAAATATGTTGCAGCTCTTCATCT
AGGTGATAAAGTAAAGGTACAATACACAAGTCAAGGTAAAAAGAAAGAATCAGTTGGTAAAGTTATTAAACTATCAAACG
GTAAAAATGGTATTGGTATCGGTTTGACAGACCATACAGAAGTATTATCTGATGTTCCTGTGGACTTTAATACTGAAGGT
GTTGGAGGACCAAGTGCAGGTTTAATGTTTACTTTAGCGATTTACGACCAATTGGTTAAAGAAGATTTACGTAAAGGACG
TAAGATTGCAGGTACTGGTACTATTGAGCAAAATGGGCATGTTGGCGATATTGGTGGAGCAGGTTTGAAAGTTGTTTCAG
CGGCTAAAAAAGGAATGGATATTTTCTTTGTTCCTAATAATCCGATCGATAAAAATGCTAAAAAAGGCAAAACAAAGGTT
CAGACGAATTATCAAGAGGCAAAAGCAGCAGCTAAGCGATTAGGTACGAAGATGAAAATTGTACCAGTTCAAAATGTTCA
GCAAGCTATTGATTATTTGAAAAAAACAAAATAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (137-203)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (242-307)

3D structure

• AlphaFold DB: A0A0E1EG10

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	69.322	94.958	0.658