Detailed information NTG0222454

Bioinformatically predicted

Overview

• Name: comEC
• Type: Machinery gene
• Locus tag: A6J40_RS16060
• Genome accession: NZ_CP020412
• Coordinates: 3644940..3647162 (-)
• Length: 740 a.a.
• NCBI ID: WP_003635596.1
• Uniprot ID: D3HKP4
• Organism: Legionella longbeachae strain FDAARGOS_201
• Function: ssDNA transport through the inner membrane (predicted from homology) DNA binding and uptake

Genomic Context

Location: 3639940..3652162

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A6J40_RS18530	cydP	3640425..3640595 (-)	171	WP_003635577.1	cytochrome oxidase putative small subunit CydP	-
A6J40_RS16035 (A6J40_16000)	-	3640589..3640975 (-)	387	WP_003635579.1	group III truncated hemoglobin	-
A6J40_RS16040 (A6J40_16005)	-	3641310..3641633 (+)	324	WP_003635583.1	hypothetical protein	-
A6J40_RS16045 (A6J40_16010)	-	3641956..3642771 (+)	816	WP_003635585.1	mechanosensitive ion channel family protein	-
A6J40_RS16050 (A6J40_16015)	-	3643197..3643424 (+)	228	WP_172622913.1	hypothetical protein	-
A6J40_RS16055 (A6J40_16020)	-	3643781..3644830 (-)	1050	WP_003635594.1	bifunctional transcriptional activator/DNA repair enzyme AdaA	-
A6J40_RS16060 (A6J40_16025)	comEC	3644940..3647162 (-)	2223	WP_003635596.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
A6J40_RS16065 (A6J40_16030)	potA	3647347..3648441 (+)	1095	WP_003635598.1	spermidine/putrescine ABC transporter ATP-binding protein PotA	-
A6J40_RS16070 (A6J40_16035)	-	3648431..3649255 (+)	825	WP_003635599.1	ABC transporter permease	-
A6J40_RS16075 (A6J40_16040)	-	3649252..3650019 (+)	768	WP_003635601.1	ABC transporter permease subunit	-
A6J40_RS16080 (A6J40_16045)	-	3650016..3651041 (+)	1026	WP_003635604.1	PotD/PotF family extracellular solute-binding protein	-
A6J40_RS16085 (A6J40_16050)	-	3651283..3651921 (+)	639	WP_003635606.1	hypothetical protein	-

Sequence

Protein

• Length: 740 a.a.
• Molecular weight: 83609.84 Da
• Isoelectric Point: 9.6797

>NTDB_id=222454 A6J40_RS16060 WP_003635596.1 3644940..3647162(-) (comEC) [Legionella longbeachae strain FDAARGOS_201]
MEIFCFFIGILYRYTLHGLLPILILFIFFIIPRYANILFFLLGIFIATVHQSQNLPKGLPDVEVIPQVSIQGTIASIPLQ
SPSKTLFLLALEQYDNHPAQGIIQLSWYNKAPKIHVGQRWKFKVKLKKPRNYLNPGSMDYVRSLATRHILWTGYIHSRGN
KQLPKVPSSFNWLELREQLSEQLGLLAPDQKTAGIVEALALNITTHIDQKSWDLFRRTGTTHLFGISGEHIALISGIIYW
LLRWIWTRSSRLCLRIPAPHIASMGGLLAASGYAFLAGFAPPVQRALIGCFFYTLYSLGYQRFTPWQVWRYALCGVLLIE
PHAVFMQGFYFSFLAVACLLLTQQRWRLKGYKASLALQLSCLIGLMPLTLYWYAYGSINGFIANLFAIPLVGLLIVPLSL
MTMTVSSLSIAKILMKAVSLLITLLFKGLSLSEYLAALNINCPIYSIELALVLIGALLMWVLLPTKPFQWIAMLWLLLPF
FPPRTIIQAGEAKIDVLDVGQGLAVAIRTQHHVLLYDTGDRFFQGNDLGKMVILPYLNTLGIKKIDTIVVSHPDKDHLGG
LKSLEKEIPVERLLVNEPHFYHRGLKCHDYPPWQWDGVSFRFLPIKIPLRGKNNSSCILQIETHAGRMLLAGDIEKIAED
YLVQTYGNILESDVLLVPHHGSKTSSSYRFLLEVAPLYAIASLGFDNRFHFPHDKTLANMKKLNIPFYRTDTCGMVQITL
PAQGALTHPTCFSGQRLQPV

Nucleotide

• Length: 2223 bp

>NTDB_id=222454 A6J40_RS16060 WP_003635596.1 3644940..3647162(-) (comEC) [Legionella longbeachae strain FDAARGOS_201]
ATGGAAATTTTTTGCTTTTTTATAGGCATATTGTATCGATATACCTTACACGGATTATTGCCTATACTTATTTTATTTAT
TTTTTTCATTATTCCCAGGTATGCGAATATCCTGTTTTTTCTTTTAGGCATCTTCATCGCGACTGTGCACCAATCTCAAA
ATTTACCAAAAGGATTACCCGATGTTGAAGTAATACCCCAAGTCAGCATCCAAGGAACAATTGCATCTATTCCGCTCCAA
AGTCCATCTAAGACACTCTTTTTATTGGCTTTAGAACAATACGACAATCATCCAGCACAAGGGATAATACAATTATCATG
GTATAACAAAGCCCCCAAAATCCATGTAGGGCAACGATGGAAATTTAAAGTGAAATTGAAAAAGCCAAGAAATTATCTAA
ATCCAGGGAGTATGGATTATGTACGTTCACTCGCAACACGCCATATATTGTGGACTGGATATATTCATTCTAGAGGAAAT
AAGCAACTCCCAAAAGTCCCCTCATCTTTCAATTGGCTAGAACTAAGGGAACAATTAAGCGAGCAACTCGGCTTGTTGGC
ACCTGATCAAAAAACCGCTGGAATTGTAGAGGCTTTAGCTTTAAATATAACAACCCATATTGACCAGAAAAGCTGGGATT
TGTTTAGACGTACTGGCACAACCCATTTATTTGGTATTTCAGGTGAACATATCGCCTTAATTTCAGGTATTATTTATTGG
TTACTCCGTTGGATATGGACTCGAAGCTCTCGTCTTTGCTTACGCATTCCAGCCCCTCATATTGCAAGTATGGGTGGCCT
TTTGGCTGCATCAGGATATGCGTTTTTAGCAGGTTTTGCACCTCCTGTCCAAAGGGCACTTATCGGATGTTTTTTTTATA
CCCTTTATAGCTTGGGCTACCAGCGTTTTACTCCATGGCAAGTATGGCGCTATGCTCTATGTGGTGTCTTATTGATTGAA
CCACATGCCGTATTTATGCAAGGATTCTATTTTTCTTTTCTTGCAGTAGCATGCTTGCTCTTAACACAACAACGCTGGCG
TTTAAAAGGATATAAAGCCTCTTTAGCCCTACAGTTAAGCTGTTTAATTGGGTTAATGCCCCTAACCTTATATTGGTATG
CTTATGGCTCAATTAATGGATTTATTGCAAACCTTTTCGCTATACCTTTGGTGGGATTACTCATTGTTCCGTTGTCATTA
ATGACAATGACGGTCAGCTCTTTAAGCATTGCAAAGATACTAATGAAGGCCGTTTCTTTACTCATTACCCTATTGTTTAA
AGGGCTATCCTTGTCAGAATATTTAGCTGCTCTAAATATTAATTGCCCCATTTATTCTATAGAACTGGCTCTTGTTCTAA
TTGGAGCTTTATTGATGTGGGTTTTACTACCCACTAAACCTTTTCAATGGATCGCGATGCTTTGGTTATTGCTCCCGTTT
TTTCCACCGCGAACAATCATTCAAGCAGGCGAAGCCAAAATAGATGTTTTGGACGTAGGGCAAGGCTTGGCTGTTGCGAT
TCGAACGCAACACCATGTATTGCTTTATGATACAGGAGATCGTTTCTTTCAAGGAAATGATTTAGGGAAAATGGTTATTT
TGCCTTATCTTAACACTTTGGGTATCAAAAAAATTGATACCATAGTTGTGAGCCATCCTGATAAAGATCATCTTGGAGGA
CTTAAATCACTGGAAAAAGAAATACCAGTAGAGAGGCTATTAGTCAATGAGCCTCATTTCTATCATCGTGGTTTAAAATG
TCATGATTATCCACCATGGCAATGGGACGGTGTTTCGTTCCGTTTTCTGCCAATAAAAATTCCCCTTAGAGGAAAAAACA
ACAGTTCTTGCATTTTACAAATAGAAACACATGCAGGACGGATGCTCTTAGCTGGCGATATTGAAAAAATAGCTGAAGAT
TATCTGGTGCAGACTTATGGCAATATTCTTGAATCAGATGTGCTGCTTGTTCCTCATCATGGCAGTAAAACTTCATCATC
CTACAGATTCTTATTAGAAGTTGCTCCGCTCTATGCTATAGCCTCCCTGGGCTTTGATAATCGCTTTCACTTTCCCCATG
ACAAGACTTTAGCAAACATGAAAAAACTGAATATCCCTTTTTACAGAACAGATACTTGTGGCATGGTACAGATTACTTTG
CCTGCCCAAGGAGCACTCACTCATCCCACTTGCTTTAGTGGACAGAGGTTACAACCCGTGTAA

Domains

Predicted by InterproScan.

• Competence protein (Competence) (201-465)

• Metallo-beta-lactamase superfamily (Lactamase_B) (498-676)

• Domain of unknown function (DUF4131) (DUF4131) (16-157)

3D structure

• AlphaFold DB: D3HKP4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC	Legionella pneumophila strain Lp02	64.305	99.189	0.638
comEC	Legionella pneumophila strain ERS1305867	63.81	99.324	0.634