Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   C2H93_RS01235 Genome accession   NZ_CP026036
Coordinates   247563..248204 (+) Length   213 a.a.
NCBI ID   WP_003244318.1    Uniprot ID   P96686
Organism   Bacillus subtilis strain PK5_16     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 242563..253204
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C2H93_RS01205 (C2H93_01185) ydfE 243757..244380 (-) 624 WP_029725823.1 flavin reductase family protein -
  C2H93_RS01210 (C2H93_01190) ydfF 244470..245150 (+) 681 WP_249852531.1 winged helix-turn-helix domain-containing protein -
  C2H93_RS01215 (C2H93_01195) ydfG 245231..245674 (-) 444 WP_014475936.1 carboxymuconolactone decarboxylase family protein -
  C2H93_RS01220 (C2H93_01200) - 245760..245939 (-) 180 WP_010886421.1 hypothetical protein -
  C2H93_RS01225 (C2H93_01205) - 245936..246079 (-) 144 WP_014478971.1 hypothetical protein -
  C2H93_RS01230 (C2H93_01210) ydfH 246347..247570 (+) 1224 WP_077671260.1 two-component system sensor histidine kinase YdfH -
  C2H93_RS01235 (C2H93_01215) vraR 247563..248204 (+) 642 WP_003244318.1 two-component system response regulator YdfI Regulator
  C2H93_RS01240 (C2H93_01220) ydfJ 248320..250491 (+) 2172 WP_249852532.1 MMPL family transporter -
  C2H93_RS01245 (C2H93_01225) ydfK 250549..251238 (-) 690 WP_015252719.1 DUF554 domain-containing protein -
  C2H93_RS01250 (C2H93_01230) ydfL 251328..252140 (-) 813 WP_249852533.1 MerR family transcriptional regulator -
  C2H93_RS01255 (C2H93_01235) mneP 252254..253147 (-) 894 WP_029317351.1 manganese transporter MneP -

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 23973.92 Da        Isoelectric Point: 5.4183

>NTDB_id=222449 C2H93_RS01235 WP_003244318.1 247563..248204(+) (vraR) [Bacillus subtilis strain PK5_16]
MNKVLIVDDHLVVREGLKLLIETNDQYTIIGEAENGKVAVRLADELEPDIILMDLYMPEMSGLEAIKQIKEKHDTPIIIL
TTYNEDHLMIEGIELGAKGYLLKDTSSETLFHTMDAAIRGNVLLQPDILKRLQEIQFERMKKQRNETQLTEKEVIVLKAI
AKGLKSKAIAFDLGVSERTVKSRLTSIYNKLGANSRTEAVTIAMQKGILTIDN

Nucleotide


Download         Length: 642 bp        

>NTDB_id=222449 C2H93_RS01235 WP_003244318.1 247563..248204(+) (vraR) [Bacillus subtilis strain PK5_16]
ATGAATAAGGTTTTAATCGTTGATGACCATCTTGTCGTGAGGGAAGGTCTGAAGCTTTTAATTGAAACGAATGATCAATA
CACCATTATAGGAGAGGCGGAAAATGGAAAAGTCGCAGTCCGTCTTGCAGATGAATTAGAACCGGATATCATTCTGATGG
ATTTGTATATGCCGGAGATGAGCGGGTTAGAGGCCATTAAACAAATAAAAGAAAAACACGATACCCCCATCATTATTTTG
ACTACATATAATGAAGATCACTTAATGATCGAAGGAATTGAATTAGGAGCGAAAGGATATCTGTTAAAGGATACGAGTTC
AGAAACCCTTTTTCACACAATGGATGCAGCGATCAGAGGAAATGTGCTGTTGCAGCCTGATATCCTCAAACGTCTGCAAG
AAATCCAATTTGAGCGGATGAAAAAGCAGCGCAATGAGACGCAGCTGACAGAAAAGGAAGTCATTGTTCTAAAAGCAATT
GCTAAAGGTCTTAAAAGCAAAGCGATTGCCTTTGATTTGGGCGTCTCTGAGCGAACAGTAAAGTCCAGATTAACGTCCAT
TTACAATAAATTAGGCGCGAATTCAAGAACTGAGGCAGTAACGATTGCCATGCAAAAAGGTATTCTGACAATAGACAACT
AA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-112)

Bacterial regulatory proteins, luxR family (GerE)

(148-203)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P96686

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

36.493

99.061

0.362