Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   A6J38_RS05230 Genome accession   NZ_CP020411
Coordinates   1073696..1074370 (-) Length   224 a.a.
NCBI ID   WP_005647998.1    Uniprot ID   Q4QLV0
Organism   Haemophilus influenzae strain FDAARGOS_199     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1068696..1079370
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A6J38_RS05210 (A6J38_05205) hinT 1070401..1070751 (+) 351 WP_005627389.1 purine nucleoside phosphoramidase -
  A6J38_RS05215 (A6J38_05210) - 1070751..1071101 (+) 351 WP_005647993.1 YcfL family protein -
  A6J38_RS05220 (A6J38_05215) nagZ 1071105..1072160 (+) 1056 WP_005693307.1 beta-N-acetylhexosaminidase -
  A6J38_RS05225 (A6J38_05220) rlmC 1072153..1073331 (+) 1179 WP_005693305.1 23S rRNA (uracil(747)-C(5))-methyltransferase RlmC -
  A6J38_RS05230 (A6J38_05225) crp 1073696..1074370 (-) 675 WP_005647998.1 cAMP-activated global transcriptional regulator CRP Regulator
  A6J38_RS05235 (A6J38_05230) - 1074355..1074606 (-) 252 WP_005647999.1 YheU family protein -
  A6J38_RS05240 (A6J38_05235) slmA 1074628..1075284 (-) 657 WP_005648000.1 nucleoid occlusion factor SlmA -
  A6J38_RS05245 (A6J38_05240) dut 1075288..1075743 (-) 456 WP_005631431.1 dUTP diphosphatase -
  A6J38_RS05250 (A6J38_05245) coaBC 1075791..1076993 (-) 1203 WP_005693302.1 bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC -
  A6J38_RS05255 (A6J38_05250) radC 1077157..1077822 (+) 666 WP_013527272.1 DNA repair protein RadC -
  A6J38_RS05260 (A6J38_05255) rpmB 1078036..1078272 (+) 237 WP_005542826.1 50S ribosomal protein L28 -
  A6J38_RS05265 (A6J38_05260) rpmG 1078284..1078454 (+) 171 WP_005613503.1 50S ribosomal protein L33 -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25151.85 Da        Isoelectric Point: 6.8375

>NTDB_id=222391 A6J38_RS05230 WP_005647998.1 1073696..1074370(-) (crp) [Haemophilus influenzae strain FDAARGOS_199]
MSNELTEIDEVVTSSQEEATQRDPVLDWFLTHCHLHKYPAKSTLIHAGEDATTLYYVIKGSVMVSSKDDEGKEMILTYLG
AGQFFGEAGLFDEGSKRSAWVKTKTTCEIAEISYKKYRQLIQANPEILMFLTAQLARRLQNTSRQVTNLAFLDVAGRIAQ
TLMNLAKQPEAMTHPDGMQIKITRQEIGQMVGCSRETVGRIIKMLEDQNLIHAHGKTIVVYGAR

Nucleotide


Download         Length: 675 bp        

>NTDB_id=222391 A6J38_RS05230 WP_005647998.1 1073696..1074370(-) (crp) [Haemophilus influenzae strain FDAARGOS_199]
ATGTCAAATGAATTAACCGAAATTGATGAAGTTGTAACCTCCTCTCAAGAAGAAGCAACTCAACGAGATCCCGTTTTAGA
TTGGTTTCTTACTCACTGCCATTTGCATAAATATCCTGCAAAATCAACTTTAATTCATGCTGGGGAAGATGCGACCACGC
TGTATTATGTAATTAAAGGTTCTGTAATGGTATCTTCAAAAGATGATGAAGGCAAAGAGATGATCCTCACTTACTTAGGT
GCAGGACAATTTTTTGGCGAAGCGGGATTATTTGATGAAGGTTCAAAACGATCAGCTTGGGTAAAAACAAAAACAACATG
TGAAATTGCTGAAATTTCCTATAAGAAATATCGCCAGTTGATTCAGGCAAACCCTGAAATCTTAATGTTTCTCACTGCAC
AATTGGCAAGACGTTTGCAAAATACATCACGTCAAGTCACGAATTTGGCATTTTTAGACGTCGCAGGTCGCATCGCTCAA
ACTTTAATGAACTTAGCTAAACAGCCTGAAGCAATGACGCATCCTGATGGTATGCAAATCAAAATTACACGCCAAGAAAT
AGGGCAAATGGTGGGTTGTTCACGAGAAACTGTGGGGCGCATTATTAAGATGTTGGAGGATCAGAATCTTATCCACGCTC
ATGGAAAAACAATCGTTGTATATGGCGCAAGATAA

Domains

Predicted by InterproScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(36-124)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(156-220)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q4QLV0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Haemophilus influenzae Rd KW20

100

100

1
  crp Vibrio cholerae strain A1552

75.49

91.071

0.687
  crp Acinetobacter baumannii D1279779

48.705

86.161

0.42

Multiple sequence alignment