Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   C2H94_RS13315 Genome accession   NZ_CP026034
Coordinates   2522889..2523530 (+) Length   213 a.a.
NCBI ID   WP_003244318.1    Uniprot ID   P96686
Organism   Bacillus subtilis strain PK5_52     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2517889..2528530
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C2H94_RS13285 (C2H94_13220) ydfE 2519083..2519706 (-) 624 WP_072175190.1 flavin reductase family protein -
  C2H94_RS13290 (C2H94_13225) ydfF 2519796..2520476 (+) 681 WP_072175191.1 winged helix-turn-helix domain-containing protein -
  C2H94_RS13295 (C2H94_13230) ydfG 2520557..2521000 (-) 444 WP_072175192.1 carboxymuconolactone decarboxylase family protein -
  C2H94_RS13300 (C2H94_13235) - 2521086..2521265 (-) 180 WP_249849607.1 hypothetical protein -
  C2H94_RS13305 (C2H94_13240) - 2521262..2521405 (-) 144 WP_014478971.1 hypothetical protein -
  C2H94_RS13310 (C2H94_13245) ydfH 2521673..2522896 (+) 1224 WP_169037916.1 two-component system sensor histidine kinase YdfH -
  C2H94_RS13315 (C2H94_13250) vraR 2522889..2523530 (+) 642 WP_003244318.1 two-component system response regulator YdfI Regulator
  C2H94_RS13320 (C2H94_13255) ydfJ 2523646..2525817 (+) 2172 WP_167568880.1 MMPL family transporter -
  C2H94_RS13325 (C2H94_13260) ydfK 2525875..2526564 (-) 690 WP_167568882.1 DUF554 domain-containing protein -
  C2H94_RS13330 (C2H94_13265) ydfL 2526654..2527466 (-) 813 WP_167568884.1 MerR family transcriptional regulator -
  C2H94_RS13335 (C2H94_13270) mneP 2527578..2528471 (-) 894 WP_070548618.1 manganese transporter MneP -

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 23973.92 Da        Isoelectric Point: 5.4183

>NTDB_id=222229 C2H94_RS13315 WP_003244318.1 2522889..2523530(+) (vraR) [Bacillus subtilis strain PK5_52]
MNKVLIVDDHLVVREGLKLLIETNDQYTIIGEAENGKVAVRLADELEPDIILMDLYMPEMSGLEAIKQIKEKHDTPIIIL
TTYNEDHLMIEGIELGAKGYLLKDTSSETLFHTMDAAIRGNVLLQPDILKRLQEIQFERMKKQRNETQLTEKEVIVLKAI
AKGLKSKAIAFDLGVSERTVKSRLTSIYNKLGANSRTEAVTIAMQKGILTIDN

Nucleotide


Download         Length: 642 bp        

>NTDB_id=222229 C2H94_RS13315 WP_003244318.1 2522889..2523530(+) (vraR) [Bacillus subtilis strain PK5_52]
ATGAATAAGGTTTTAATCGTTGATGACCATCTTGTCGTGAGGGAAGGTCTGAAGCTTTTAATTGAAACGAATGATCAATA
CACCATTATAGGAGAGGCGGAAAATGGAAAAGTCGCAGTCCGTCTTGCAGATGAATTAGAACCGGATATCATTCTGATGG
ATTTGTATATGCCGGAGATGAGCGGGTTAGAGGCCATTAAACAAATAAAAGAAAAACACGATACCCCCATCATTATTTTG
ACTACATATAATGAAGATCACTTAATGATCGAGGGGATTGAATTAGGAGCGAAAGGATATCTGTTAAAGGATACGAGTTC
AGAAACCCTTTTTCACACAATGGATGCAGCGATCAGAGGAAATGTGCTGTTGCAGCCTGATATCCTCAAACGTCTGCAAG
AAATCCAATTTGAGCGGATGAAAAAGCAGCGCAATGAGACGCAGCTGACAGAAAAGGAAGTCATTGTTCTAAAAGCAATT
GCTAAAGGTCTTAAAAGCAAAGCGATTGCCTTTGATTTGGGCGTCTCTGAGCGAACAGTAAAGTCCAGATTAACGTCCAT
TTACAATAAATTAGGCGCGAATTCAAGAACTGAGGCAGTAACGATTGCCATGCAAAAAGGTATTCTGACAATAGACAACT
AA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-112)

Bacterial regulatory proteins, luxR family (GerE)

(148-203)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P96686

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

36.493

99.061

0.362

Multiple sequence alignment