Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutX   Type   Machinery gene
Locus tag   SP_RS05760 Genome accession   NC_003028
Coordinates   1104364..1104828 (-) Length   154 a.a.
NCBI ID   WP_001135768.1    Uniprot ID   A4L7L7
Organism   Streptococcus pneumoniae TIGR4     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1099364..1109828
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SP_RS05740 (SP_1164) - 1100315..1101283 (-) 969 WP_000105360.1 thiamine pyrophosphate-dependent dehydrogenase E1 component subunit alpha -
  SP_RS05745 (SP_1166) pdrM 1101437..1102798 (-) 1362 WP_000278525.1 sodium-coupled multidrug efflux MATE transporter PdrM -
  SP_RS05750 - 1102809..1103069 (-) 261 WP_001105925.1 hypothetical protein -
  SP_RS05755 (SP_1167) - 1103083..1104351 (-) 1269 WP_000924508.1 dihydroorotase -
  SP_RS05760 (SP_1168) mutX 1104364..1104828 (-) 465 WP_001135768.1 NUDIX hydrolase Machinery gene
  SP_RS05765 (SP_1169) - 1104838..1105491 (-) 654 WP_000401326.1 uracil-DNA glycosylase -
  SP_RS05770 (SP_1170) - 1105629..1106231 (-) 603 WP_001812270.1 hypothetical protein -
  SP_RS05775 (SP_1171) - 1106289..1107002 (-) 714 WP_000499429.1 YjjG family noncanonical pyrimidine nucleotidase -
  SP_RS05780 (SP_1173) dhaM 1107462..1107836 (-) 375 WP_000443795.1 dihydroxyacetone kinase phosphoryl donor subunit DhaM -
  SP_RS13790 - 1107836..1107910 (-) 75 Protein_1108 dihydroxyacetone kinase subunit L -

Sequence

Protein


Download         Length: 154 a.a.        Molecular weight: 17812.16 Da        Isoelectric Point: 4.2287

>NTDB_id=22221 SP_RS05760 WP_001135768.1 1104364..1104828(-) (mutX) [Streptococcus pneumoniae TIGR4]
MPQLATICYIDNGKELLMLHRNKKPNDVHEGKWIGVGGKLERGETPQECAAREILEETGLKAKPVLKGVITFPEFTPDLD
WYTYVFKVTEFEGDLIDCNEGTLEWVPYDEVLSKPTWEGDHTFVEWLLEDKPFFSAKFVYDGDKLLDTQVDFYE

Nucleotide


Download         Length: 465 bp        

>NTDB_id=22221 SP_RS05760 WP_001135768.1 1104364..1104828(-) (mutX) [Streptococcus pneumoniae TIGR4]
ATGCCTCAGTTAGCGACGATTTGCTACATTGATAATGGGAAAGAACTGCTCATGCTCCATCGTAATAAGAAACCCAATGA
TGTCCATGAAGGGAAATGGATTGGTGTGGGTGGTAAGCTAGAGAGAGGAGAGACGCCCCAGGAATGCGCGGCGCGTGAAA
TCCTTGAAGAAACAGGGCTCAAAGCCAAGCCAGTTCTAAAAGGTGTCATCACTTTTCCTGAATTTACACCAGATTTAGAC
TGGTACACCTATGTTTTTAAGGTGACGGAGTTTGAGGGCGACTTGATTGACTGCAATGAGGGGACGCTAGAATGGGTTCC
CTATGATGAGGTTTTGAGCAAGCCGACTTGGGAAGGTGACCACACCTTTGTTGAGTGGCTTTTAGAGGATAAACCCTTCT
TTTCAGCCAAGTTTGTTTATGATGGGGATAAATTGTTGGATACCCAAGTTGATTTCTATGAATAA

Domains

Predicted by InterProScan.

NUDIX domain (NUDIX)

(2-127)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A4L7L7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutX Streptococcus pneumoniae R6

98.701

100

0.987

Multiple sequence alignment