Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilA   Type   Machinery gene
Locus tag   A6J54_RS02580 Genome accession   NZ_CP020402
Coordinates   442496..443761 (-) Length   421 a.a.
NCBI ID   WP_080541918.1    Uniprot ID   -
Organism   Neisseria meningitidis strain FDAARGOS_215     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 437496..448761
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A6J54_RS02560 (A6J54_02500) - 441298..441582 (-) 285 WP_002216166.1 GIY-YIG nuclease family protein -
  A6J54_RS02580 (A6J54_02510) pilA 442496..443761 (-) 1266 WP_080541918.1 signal recognition particle-docking protein FtsY Machinery gene
  A6J54_RS02590 (A6J54_02520) msrAB 443907..445475 (+) 1569 WP_002216163.1 bifunctional peptide-methionine (S)-S-oxide reductase MsrA/peptide-methionine (R)-S-oxide reductase MsrB -
  A6J54_RS02595 (A6J54_02525) - 445577..446062 (-) 486 WP_080541920.1 CinA family protein -
  A6J54_RS02600 (A6J54_02530) - 446089..446937 (-) 849 WP_080541921.1 mechanosensitive ion channel family protein -
  A6J54_RS02605 (A6J54_02535) - 447031..448032 (-) 1002 WP_080541922.1 thiamine ABC transporter substrate-binding protein -

Sequence

Protein


Download         Length: 421 a.a.        Molecular weight: 45173.41 Da        Isoelectric Point: 4.5275

>NTDB_id=222202 A6J54_RS02580 WP_080541918.1 442496..443761(-) (pilA) [Neisseria meningitidis strain FDAARGOS_215]
MFSFFRRKKKQETPAPEEAQIQETAAKTESETDQVIENIKEDAESLAESVKGQVESAVETVSGAVEQVKEAVAEMLSEAE
EAAEKAAEQVEAAKEAIAETVGEAVGQVQEAVATTEEHKLGWAARLKQGLTKSRDKMAKSLAGVFGGGQIDEDLYEELET
VLITSDMGMEATEYLMKDVRDRVSLKGLKDGNELRGALKEALYDLIKPLEKPLVLPETKEPFVIMLAGINGAGKTTSIGK
LAKYFQAQGKSVLLAAGDTFRAAAREQLQAWGERNNVTVISQTTGDSAAVCFDAVQAAKARGIDIVLADTAGRLPTQLHL
MEEIKKVKRVLQKAMPDAPHEIIVVLDANIGQNAVNQVKAFDDALGLTGLIVTKLDGTAKGGILAALASDRPVPVRYIGV
GEGIDDLRPFDARAFVDALLD

Nucleotide


Download         Length: 1266 bp        

>NTDB_id=222202 A6J54_RS02580 WP_080541918.1 442496..443761(-) (pilA) [Neisseria meningitidis strain FDAARGOS_215]
ATGTTCAGCTTCTTCCGTCGCAAGAAAAAACAGGAAACTCCGGCTCCCGAGGAGGCTCAAATTCAGGAAACCGCAGCAAA
AACAGAGTCCGAAACCGATCAAGTAATTGAAAATATTAAAGAAGATGCTGAATCTTTAGCAGAAAGCGTCAAAGGGCAGG
TCGAATCTGCCGTTGAAACCGTCAGCGGTGCGGTTGAACAAGTAAAGGAAGCCGTTGCCGAGATGCTGTCTGAAGCAGAG
GAAGCGGCGGAAAAAGCAGCGGAACAAGTCGAAGCGGCAAAAGAAGCCATTGCCGAAACCGTCGGCGAGGCTGTCGGGCA
AGTTCAAGAAGCCGTTGCAACAACTGAAGAACACAAGCTCGGTTGGGCGGCGCGTTTGAAACAAGGTTTGACCAAATCGC
GCGACAAAATGGCGAAATCGCTGGCGGGCGTGTTCGGCGGCGGACAAATCGACGAAGATTTGTACGAAGAGCTGGAAACC
GTGCTGATTACCAGCGACATGGGCATGGAAGCCACCGAATACCTGATGAAAGACGTGCGCGACCGTGTCAGCCTCAAAGG
GCTGAAAGACGGCAACGAATTGCGCGGCGCGTTGAAAGAAGCCTTGTACGACCTGATTAAGCCTCTGGAAAAACCATTGG
TCTTGCCCGAAACCAAAGAGCCGTTTGTCATCATGCTTGCCGGCATCAACGGCGCGGGCAAAACCACGTCTATCGGCAAA
CTCGCCAAATATTTCCAAGCGCAGGGCAAATCCGTATTGCTGGCGGCAGGCGACACTTTCCGCGCCGCCGCCCGTGAGCA
GCTTCAGGCATGGGGCGAACGCAACAACGTTACCGTGATTTCGCAAACCACGGGCGATTCCGCCGCCGTGTGCTTCGATG
CCGTCCAAGCCGCCAAAGCGCGCGGCATCGACATCGTGCTTGCCGACACCGCCGGCCGCCTGCCCACGCAGCTTCATTTG
ATGGAAGAAATCAAAAAAGTGAAACGCGTGCTGCAAAAAGCCATGCCCGACGCGCCGCACGAAATCATCGTCGTGCTTGA
TGCCAACATCGGGCAAAACGCCGTCAACCAAGTCAAAGCCTTTGACGACGCATTAGGGCTGACCGGTTTAATCGTGACCA
AACTCGACGGCACGGCAAAAGGCGGCATCCTCGCCGCGCTTGCCTCCGACCGCCCCGTCCCCGTCCGCTACATCGGCGTG
GGCGAAGGCATAGACGATTTGCGCCCGTTTGACGCGCGCGCGTTTGTGGACGCACTGCTGGATTGA

Domains

Predicted by InterproScan.

SRP54-type protein, helical bundle domain (SRP54_N)

(136-202)

SRP54-type protein, GTPase domain (SRP54)

(221-420)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilA Neisseria gonorrhoeae MS11

93.349

100

0.933

Multiple sequence alignment