Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   C2H82_RS18170 Genome accession   NZ_CP026027
Coordinates   3469435..3470067 (+) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain LIM     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 3464435..3475067
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C2H82_RS18140 yheS 3464604..3466517 (+) 1914 WP_000634798.1 ABC transporter ATP-binding protein -
  C2H82_RS18145 yheT 3466517..3467539 (+) 1023 WP_000057356.1 hydrolase -
  C2H82_RS18150 yheU 3467533..3467751 (+) 219 WP_000907085.1 YheU family protein -
  C2H82_RS18155 prkB 3467805..3468674 (+) 870 WP_001274680.1 phosphoribulokinase -
  C2H82_RS18160 yhfA 3468729..3469133 (-) 405 WP_001148908.1 OsmC family protein -
  C2H82_RS18170 crp 3469435..3470067 (+) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  C2H82_RS18175 yhfK 3470118..3472208 (+) 2091 WP_001295162.1 YccS/YhfK family putative transporter -
  C2H82_RS18180 argD 3472275..3473495 (-) 1221 WP_000963792.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  C2H82_RS18185 pabA 3473581..3474144 (-) 564 WP_000601847.1 aminodeoxychorismate synthase component 2 -
  C2H82_RS18190 fic 3474176..3474778 (-) 603 WP_001280641.1 putative adenosine monophosphate-protein transferase Fic -
  C2H82_RS18195 yhfG 3474768..3474935 (-) 168 WP_000736862.1 YhfG family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=221876 C2H82_RS18170 WP_000242755.1 3469435..3470067(+) (crp) [Escherichia coli strain LIM]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=221876 C2H82_RS18170 WP_000242755.1 3469435..3470067(+) (crp) [Escherichia coli strain LIM]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTTTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCAGACGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATTGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment