Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   FORC59_RS10195 Genome accession   NZ_CP020354
Coordinates   2001183..2001899 (+) Length   238 a.a.
NCBI ID   WP_000688498.1    Uniprot ID   Q2VG52
Organism   Staphylococcus aureus strain FORC59     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1996183..2006899
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FORC59_RS10165 (FORC59_1860) - 1996399..1997025 (+) 627 WP_000522384.1 nitroreductase family protein -
  FORC59_RS10170 (FORC59_1861) - 1997386..1998171 (+) 786 WP_000867939.1 carbon-nitrogen family hydrolase -
  FORC59_RS14365 hld 1998771..1998851 (-) 81 WP_000046022.1 delta-hemolysin -
  FORC59_RS10180 (FORC59_1863) agrB 1999141..1999710 (+) 570 WP_001105707.1 accessory gene regulator AgrB -
  FORC59_RS10185 (FORC59_1864) agrD 1999707..1999847 (+) 141 WP_001093929.1 cyclic lactone autoinducer peptide AgrD -
  FORC59_RS10190 agrC 1999872..2001164 (+) 1293 WP_001657119.1 quorum-sensing sensor histidine kinase AgrC -
  FORC59_RS10195 (FORC59_1866) agrA 2001183..2001899 (+) 717 WP_000688498.1 quorum-sensing response regulator AgrA Regulator
  FORC59_RS10200 - 2001971..2002080 (+) 110 Protein_1897 hypothetical protein -
  FORC59_RS10205 (FORC59_1867) - 2002268..2003227 (-) 960 WP_001253302.1 carbohydrate kinase family protein -
  FORC59_RS10210 (FORC59_1868) - 2003224..2004708 (-) 1485 WP_000141435.1 sucrose-6-phosphate hydrolase -
  FORC59_RS10215 (FORC59_1869) - 2004857..2005807 (-) 951 WP_000790326.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27933.91 Da        Isoelectric Point: 6.0927

>NTDB_id=221708 FORC59_RS10195 WP_000688498.1 2001183..2001899(+) (agrA) [Staphylococcus aureus strain FORC59]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSRDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=221708 FORC59_RS10195 WP_000688498.1 2001183..2001899(+) (agrA) [Staphylococcus aureus strain FORC59]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGCTTACAATTAT
TATCAAGAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCGCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-237)

Response regulator receiver domain (Response_reg)

(3-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q2VG52

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

99.58

100

0.996

Multiple sequence alignment