Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   BS11774_RS05365 Genome accession   NZ_CP026010
Coordinates   1031872..1033074 (-) Length   400 a.a.
NCBI ID   WP_106610979.1    Uniprot ID   -
Organism   Bacillus subtilis strain ATCC 11774     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1026872..1038074
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BS11774_RS05340 (BS11774_05315) - 1027807..1029273 (-) 1467 WP_128473455.1 HAMP domain-containing sensor histidine kinase -
  BS11774_RS05345 (BS11774_05320) - 1029270..1029953 (-) 684 WP_128473456.1 response regulator transcription factor -
  BS11774_RS05350 (BS11774_05325) - 1030165..1031064 (+) 900 WP_041337903.1 PepSY domain-containing protein -
  BS11774_RS05355 (BS11774_05330) - 1031226..1031726 (+) 501 WP_003226943.1 PepSY domain-containing protein -
  BS11774_RS05360 - 1031723..1031852 (-) 130 Protein_1034 hypothetical protein -
  BS11774_RS05365 (BS11774_05335) htrA 1031872..1033074 (-) 1203 WP_106610979.1 serine protease HtrC Regulator
  BS11774_RS05370 (BS11774_05340) vicX 1033156..1033950 (-) 795 WP_003226939.1 MBL fold metallo-hydrolase Regulator
  BS11774_RS05375 (BS11774_05345) walI 1033972..1034814 (-) 843 WP_003244037.1 WalRK two-component regulatory system regulator WalI -
  BS11774_RS05380 (BS11774_05350) walH 1034801..1036168 (-) 1368 WP_032722849.1 WalRK two-component regulatory system regulator WalH -
  BS11774_RS05385 (BS11774_05355) walK 1036158..1037993 (-) 1836 WP_009968432.1 cell wall metabolism sensor histidine kinase WalK -

Sequence

Protein


Download         Length: 400 a.a.        Molecular weight: 42783.56 Da        Isoelectric Point: 5.5317

>NTDB_id=221620 BS11774_RS05365 WP_106610979.1 1031872..1033074(-) (htrA) [Bacillus subtilis strain ATCC 11774]
MVDYEREEEHTTPEQPKRSKKGYFLSSLIGVIVGAVLMAFIMPYLSNEGLDTGALDQQQNNNGRESIRTVNVSVNNAVTK
IVSNVSPAVVGVVNIQKSDIWGESGEAGSGSGVIYKKNDHSAYVVTNHHVIEGASQIEISLKDGSRISAELVGSDQLMDL
AVLRVKSNKIKAVADFGNSDKVKSGEPVIAIGNPLGLEFAGSVTQGVISGTERAIPVDSNGDGQPDWNAEVLQTDAAINP
GNSGGALLNMDGKVIGINSMKIAESAVEGIGLSIPSKLVIPVIEDLERYGKVKRPFLGIEMKSLSDIASYHWDETLKLPK
NVTNGAVVMGVDAFSPAGKAGLKELDVITEFDGYKVNDIVDLRKRLYQKKVGDRVKVKFYRGGKEKSVDIKLSSADQLGS

Nucleotide


Download         Length: 1203 bp        

>NTDB_id=221620 BS11774_RS05365 WP_106610979.1 1031872..1033074(-) (htrA) [Bacillus subtilis strain ATCC 11774]
ATGGTGGATTACGAACGTGAGGAAGAACATACTACTCCTGAACAGCCAAAGAGAAGCAAAAAAGGATATTTTCTTTCGAG
TCTGATTGGCGTGATTGTCGGTGCCGTATTAATGGCGTTTATCATGCCGTACCTTTCAAATGAAGGGCTGGATACAGGCG
CCTTAGATCAGCAGCAAAACAACAATGGCCGGGAATCAATCAGGACGGTGAATGTCAGTGTCAACAATGCCGTCACCAAG
ATTGTCAGCAATGTGTCGCCCGCCGTTGTCGGTGTTGTGAACATCCAAAAATCAGATATTTGGGGAGAGAGCGGCGAGGC
TGGGAGCGGCTCTGGCGTCATCTATAAGAAAAATGACCATTCCGCTTATGTCGTGACCAACCATCATGTCATCGAAGGCG
CTTCCCAAATTGAAATCAGCTTGAAAGACGGTTCACGCATATCAGCTGAACTTGTCGGCAGCGACCAGCTGATGGACCTT
GCCGTTTTACGGGTGAAAAGCAATAAAATTAAAGCAGTCGCAGATTTCGGAAATTCAGATAAAGTGAAGTCTGGCGAGCC
GGTTATTGCGATCGGGAATCCGTTAGGCCTTGAGTTTGCAGGCTCTGTCACACAAGGCGTCATCTCAGGTACGGAGAGGG
CGATCCCAGTGGATTCAAACGGTGATGGACAGCCTGACTGGAACGCAGAAGTCCTGCAAACAGATGCGGCCATTAACCCT
GGGAACAGCGGCGGTGCTTTGTTAAATATGGATGGGAAGGTCATTGGCATCAATTCAATGAAAATTGCCGAGTCGGCGGT
TGAAGGGATTGGCCTGTCGATTCCATCTAAGCTCGTGATCCCTGTGATAGAGGATTTAGAGAGATACGGAAAGGTCAAAC
GCCCGTTCCTTGGCATTGAGATGAAATCGCTAAGTGACATCGCAAGCTATCATTGGGATGAAACATTAAAGCTTCCTAAG
AACGTCACCAATGGAGCGGTTGTGATGGGTGTAGACGCCTTTTCACCTGCCGGAAAAGCGGGGCTGAAGGAACTGGATGT
CATCACGGAATTTGACGGATACAAAGTAAATGATATTGTTGACCTGCGAAAACGGCTTTATCAGAAAAAAGTCGGTGACC
GGGTGAAGGTGAAGTTTTACCGCGGCGGAAAAGAAAAATCTGTTGACATCAAGCTGTCGTCCGCAGACCAATTAGGCAGT
TAA

Domains

Predicted by InterProScan.

PDZ domain (PDZ_2)

(295-392)

Trypsin-like peptidase domain (Trypsin_2)

(110-257)

Peptidase family M50 (Peptidase_M50)

(199-395)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

43.577

99.25

0.433
  htrA Streptococcus gordonii str. Challis substr. CH1

41.294

100

0.415
  htrA Streptococcus mitis NCTC 12261

43.005

96.5

0.415
  htrA Streptococcus pneumoniae TIGR4

45.152

82.5

0.373
  htrA Streptococcus pneumoniae D39

45.152

82.5

0.373
  htrA Streptococcus pneumoniae Rx1

45.152

82.5

0.373
  htrA Streptococcus pneumoniae R6

45.152

82.5

0.373

Multiple sequence alignment