Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   B4U62_RS17135 Genome accession   NZ_CP020102
Coordinates   3252819..3253463 (-) Length   214 a.a.
NCBI ID   WP_003220716.1    Uniprot ID   -
Organism   Bacillus subtilis strain NCIB 3610     
Function   promoting transcription of comS (predicted from homology)   
Competence regulation

Genomic Context

Location: 3247819..3258463
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  B4U62_RS17100 (B4U62_17100) mrpB 3249011..3249442 (+) 432 WP_003228819.1 Na(+)/H(+) antiporter subunit B -
  B4U62_RS17105 (B4U62_17105) mrpC 3249442..3249783 (+) 342 WP_003220730.1 Na(+)/H(+) antiporter subunit C -
  B4U62_RS17110 (B4U62_17110) mrpD 3249776..3251257 (+) 1482 WP_003244432.1 Na+/H+ antiporter subunit D -
  B4U62_RS17115 (B4U62_17115) mrpE 3251263..3251739 (+) 477 WP_003244015.1 Na+/H+ antiporter subunit E -
  B4U62_RS17120 (B4U62_17120) mrpF 3251739..3252023 (+) 285 WP_003228814.1 Na(+)/H(+) antiporter subunit F1 -
  B4U62_RS17125 (B4U62_17125) mnhG 3252007..3252381 (+) 375 WP_003244302.1 monovalent cation/H(+) antiporter subunit G -
  B4U62_RS17130 (B4U62_17130) yuxO 3252420..3252800 (-) 381 WP_003228810.1 hotdog fold thioesterase -
  B4U62_RS17135 (B4U62_17135) comA 3252819..3253463 (-) 645 WP_003220716.1 two-component system response regulator ComA Regulator
  B4U62_RS17140 (B4U62_17140) comP 3253544..3255853 (-) 2310 WP_003242894.1 two-component system sensor histidine kinase ComP Regulator
  B4U62_RS17145 (B4U62_17145) comX 3255868..3256035 (-) 168 WP_003242801.1 competence pheromone ComX Regulator
  B4U62_RS17150 (B4U62_17150) comQ 3256023..3256922 (-) 900 WP_003243039.1 ComX modifying isoprenyl transferase ComQ Regulator
  B4U62_RS17155 (B4U62_17155) degQ 3257107..3257247 (-) 141 WP_003220708.1 degradation enzyme regulation protein DegQ Regulator
  B4U62_RS22935 - 3257469..3257594 (+) 126 WP_003228793.1 hypothetical protein -
  B4U62_RS17160 (B4U62_17160) - 3257708..3258076 (+) 369 WP_003243784.1 hypothetical protein -

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 24128.51 Da        Isoelectric Point: 4.6857

>NTDB_id=221190 B4U62_RS17135 WP_003220716.1 3252819..3253463(-) (comA) [Bacillus subtilis strain NCIB 3610]
MKKILVIDDHPAVMEGTKTILETDSNLSVDCLSPEPSEQFIKQHDFSSYDLILMDLNLGGEVNGMELSKQILQENPHCKI
IVYTGYEVEDYFEEAIRAGLHGAISKTESKEKITQYIYHVLNGEILVDFAYFKQLMTQQKTKPAPSSQKEQDVLTPRECL
ILQEVEKGFTNQEIADALHLSKRSIEYSLTSIFNKLNVGSRTEAVLIAKSDGVL

Nucleotide


Download         Length: 645 bp        

>NTDB_id=221190 B4U62_RS17135 WP_003220716.1 3252819..3253463(-) (comA) [Bacillus subtilis strain NCIB 3610]
ATGAAAAAGATACTAGTGATTGATGACCATCCGGCTGTCATGGAAGGCACCAAGACAATTTTGGAAACGGATTCGAATTT
GTCTGTTGATTGTCTCAGTCCTGAACCGAGCGAACAGTTTATCAAGCAGCATGATTTCTCGTCATATGATCTCATTTTAA
TGGATCTGAATCTAGGCGGCGAGGTCAATGGGATGGAGCTTTCTAAACAGATTTTACAAGAGAATCCTCATTGTAAAATT
ATCGTGTATACCGGTTATGAGGTCGAGGATTATTTCGAGGAAGCGATTCGTGCGGGTCTGCACGGTGCCATCAGCAAAAC
GGAATCTAAAGAAAAGATCACCCAATACATATACCACGTACTCAACGGAGAAATTTTAGTCGATTTTGCTTACTTTAAAC
AGCTGATGACTCAGCAAAAAACAAAGCCGGCTCCTTCCTCTCAAAAAGAACAAGATGTGCTCACACCTAGAGAATGCCTG
ATTCTTCAAGAAGTTGAAAAGGGATTTACAAACCAAGAAATCGCAGATGCCCTTCATTTAAGCAAGCGGTCCATTGAATA
CAGCTTGACATCGATTTTCAATAAGCTGAATGTCGGTTCACGGACGGAAGCGGTTTTGATTGCGAAATCAGACGGTGTAC
TTTAA

Domains

Predicted by InterproScan.

Bacterial regulatory proteins, luxR family (GerE)

(152-208)

Response regulator receiver domain (Response_reg)

(4-117)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Bacillus subtilis subsp. subtilis str. 168

100

100

1

Multiple sequence alignment