Detailed information NTG0022106

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: MW_RS13815
• Genome accession: NC_003923
• Coordinates: 2715133..2716020 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143417.1
• Uniprot ID: A0A641A7I7
• Organism: Staphylococcus aureus subsp. aureus MW2
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2710133..2721020

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MW_RS13780	-	2710152..2710244 (+)	93	WP_010956583.1	hypothetical protein	-
MW_RS13785 (MW2541)	-	2710352..2710849 (-)	498	WP_001065268.1	glutathione peroxidase	-
MW_RS13790	-	2710859..2711119 (-)	261	WP_001791974.1	hypothetical protein	-
MW_RS13795	-	2711501..2711614 (-)	114	Protein_2617	hypothetical protein	-
MW_RS13805 (MW2542)	-	2712273..2714273 (-)	2001	WP_000776740.1	ABC transporter permease	-
MW_RS13810 (MW2543)	-	2714270..2715025 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
MW_RS13815 (MW2544)	braS	2715133..2716020 (-)	888	WP_000143417.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
MW_RS13820 (MW2545)	braR	2716031..2716696 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
MW_RS13825 (MW2546)	-	2716722..2716922 (-)	201	WP_000604727.1	hypothetical protein	-
MW_RS13835 (MW2547)	-	2717120..2718544 (+)	1425	WP_000953748.1	alkaline phosphatase	-
MW_RS15455	-	2718604..2718705 (-)	102	WP_000731972.1	SE2200 family small protein	-
MW_RS13840 (MW2549)	-	2718827..2719282 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
MW_RS13845 (MW2550)	-	2719527..2720288 (-)	762	WP_000323441.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34027.28 Da
• Isoelectric Point: 5.8962

>NTDB_id=22106 MW_RS13815 WP_000143417.1 2715133..2716020(-) (braS) [Staphylococcus aureus subsp. aureus MW2]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLLIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=22106 MW_RS13815 WP_000143417.1 2715133..2716020(-) (braS) [Staphylococcus aureus subsp. aureus MW2]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTACTGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGTCAAAGTAACTCAAGTGGGATTGGCTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (192-294)

3D structure

• AlphaFold DB: A0A641A7I7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	98.983	100	0.99