Detailed information    

insolico Bioinformatically predicted

Overview

Name   sepM   Type   Regulator
Locus tag   B5D85_RS06660 Genome accession   NZ_CP020082
Coordinates   1267163..1268200 (-) Length   345 a.a.
NCBI ID   WP_076639313.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain STAB120304     
Function   processing of CSP (predicted from homology)   
Competence regulation

Genomic Context

Location: 1262163..1273200
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  B5D85_RS06640 (B5D85_06620) - 1262913..1263539 (+) 627 WP_002983834.1 prepilin peptidase -
  B5D85_RS06645 (B5D85_06625) rlmN 1263621..1264700 (-) 1080 WP_020905325.1 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN -
  B5D85_RS06650 (B5D85_06630) - 1264704..1265324 (-) 621 WP_002992791.1 YutD family protein -
  B5D85_RS06655 (B5D85_06635) - 1265772..1266749 (-) 978 WP_002994809.1 LacI family DNA-binding transcriptional regulator -
  B5D85_RS06660 (B5D85_06640) sepM 1267163..1268200 (-) 1038 WP_076639313.1 SepM family pheromone-processing serine protease Regulator
  B5D85_RS06665 (B5D85_06645) coaD 1268187..1268678 (-) 492 WP_002983821.1 pantetheine-phosphate adenylyltransferase -
  B5D85_RS06670 (B5D85_06650) rsmD 1268668..1269207 (-) 540 WP_002983819.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  B5D85_RS06675 (B5D85_06655) asnA 1269330..1270322 (-) 993 WP_020905328.1 aspartate--ammonia ligase -
  B5D85_RS06680 (B5D85_06660) arcC 1270635..1271585 (-) 951 WP_010922501.1 carbamate kinase -
  B5D85_RS06685 (B5D85_06665) - 1271605..1272936 (-) 1332 WP_011054719.1 dipeptidase -

Sequence

Protein


Download         Length: 345 a.a.        Molecular weight: 37571.27 Da        Isoelectric Point: 9.6692

>NTDB_id=220923 B5D85_RS06660 WP_076639313.1 1267163..1268200(-) (sepM) [Streptococcus pyogenes strain STAB120304]
MKRLKKIKWWLVGLLALISLLLALFFPLPYYIEMPGGAYDIRTVLQVNGKEDKRKGAYQFVAVGISRASLAQLLYAWLTP
FTEISTAEDTTGGYSDADFLRINQFYMETSQNAAIYQALSLAGKPVTLDYKGVYVLDVNNESTFKGTLHLTDTVTGVNGK
QFTSSAELIDYVSHLKLGDEVTVQFTSDNKPKKGVGRIIKLKNGKNGIGIALTDHTSVNSEDTVIFSTKGVGGPSAGLMF
TLDIYDQITKEDLRKGRTIAGTGTIGKDGEVGDIGGAGLKVVAAAEAGADIFFVPNNPVDKEIKKVNPNAISNYEEAKRA
AKRLKTKMKIVPVTTVQEALVYLRK

Nucleotide


Download         Length: 1038 bp        

>NTDB_id=220923 B5D85_RS06660 WP_076639313.1 1267163..1268200(-) (sepM) [Streptococcus pyogenes strain STAB120304]
ATGAAAAGACTTAAAAAAATCAAATGGTGGTTAGTGGGTCTGCTAGCTTTAATCTCTTTGTTGCTAGCGTTATTTTTTCC
GCTACCTTATTATATTGAAATGCCTGGAGGCGCTTACGATATTCGGACTGTCTTACAAGTCAATGGCAAAGAAGACAAAC
GAAAAGGAGCTTACCAGTTTGTTGCAGTGGGCATTAGTCGTGCCAGCCTCGCTCAGCTATTATATGCTTGGCTGACACCG
TTTACTGAAATTAGTACAGCAGAAGATACAACAGGCGGATACAGCGATGCTGATTTCCTTCGAATTAATCAATTTTACAT
GGAAACATCACAAAATGCAGCTATTTATCAAGCTTTATCCTTAGCTGGAAAACCAGTTACATTAGATTATAAAGGCGTAT
ATGTTTTAGATGTAAACAACGAATCTACTTTTAAAGGAACGTTACACTTAACAGATACTGTAACAGGTGTAAATGGTAAA
CAGTTTACTAGTTCAGCAGAACTTATTGACTATGTTTCTCACCTAAAACTAGGGGATGAAGTTACGGTTCAGTTTACGAG
TGATAATAAGCCTAAAAAAGGAGTTGGCCGTATTATCAAACTGAAAAATGGGAAAAATGGGATTGGCATTGCCTTGACTG
ATCATACAAGTGTCAATTCAGAAGACACAGTGATCTTTAGTACTAAAGGAGTAGGAGGACCTAGTGCTGGTCTAATGTTT
ACTCTTGATATATATGATCAAATAACTAAAGAAGATTTACGCAAGGGCCGTACAATTGCAGGTACAGGAACTATTGGCAA
GGATGGCGAAGTAGGAGATATTGGTGGTGCAGGTCTTAAAGTAGTTGCAGCAGCTGAAGCTGGTGCAGATATATTTTTTG
TTCCGAATAATCCTGTTGATAAGGAAATTAAAAAAGTTAATCCAAATGCTATAAGTAATTACGAAGAAGCCAAACGGGCA
GCCAAACGACTAAAGACCAAAATGAAGATTGTTCCTGTTACGACTGTTCAAGAGGCACTGGTTTATCTTCGCAAATAA

Domains

Predicted by InterproScan.

Lon protease (S16) C-terminal proteolytic domain (Lon_C)

(233-309)

PDZ domain (PDZ_2)

(129-192)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sepM Streptococcus mutans UA159

68.986

100

0.69

Multiple sequence alignment