Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   CXV43_RS19230 Genome accession   NZ_CP025903
Coordinates   3851551..3852183 (+) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain 300709     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 3846551..3857183
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CXV43_RS19205 yheS 3846720..3848633 (+) 1914 WP_000634798.1 ABC transporter ATP-binding protein -
  CXV43_RS19210 yheT 3848633..3849655 (+) 1023 WP_000057356.1 hydrolase -
  CXV43_RS19215 yheU 3849649..3849867 (+) 219 WP_000907085.1 YheU family protein -
  CXV43_RS19220 prkB 3849921..3850790 (+) 870 WP_001274680.1 phosphoribulokinase -
  CXV43_RS19225 yhfA 3850845..3851249 (-) 405 WP_001148908.1 OsmC family protein -
  CXV43_RS19230 crp 3851551..3852183 (+) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  CXV43_RS19235 yhfK 3852234..3854324 (+) 2091 WP_001295162.1 YccS/YhfK family putative transporter -
  CXV43_RS19240 argD 3854391..3855611 (-) 1221 WP_000963792.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  CXV43_RS19245 pabA 3855697..3856260 (-) 564 WP_001737557.1 aminodeoxychorismate synthase component 2 -
  CXV43_RS19250 fic 3856292..3856894 (-) 603 WP_001280641.1 putative adenosine monophosphate-protein transferase Fic -
  CXV43_RS19255 yhfG 3856884..3857051 (-) 168 WP_000736862.1 YhfG family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=220923 CXV43_RS19230 WP_000242755.1 3851551..3852183(+) (crp) [Escherichia coli strain 300709]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=220923 CXV43_RS19230 WP_000242755.1 3851551..3852183(+) (crp) [Escherichia coli strain 300709]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTTTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCAGACGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATTGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment