Detailed information    

insolico Bioinformatically predicted

Overview

Name   pepF   Type   Regulator
Locus tag   GTHT12_RS04360 Genome accession   NZ_CP020030
Coordinates   862712..864535 (+) Length   607 a.a.
NCBI ID   WP_011886942.1    Uniprot ID   A4IL78
Organism   Geobacillus thermodenitrificans strain T12     
Function   degradation of XIP; competence shut-off (predicted from homology)   
Competence regulation

Genomic Context

Location: 857712..869535
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GTHT12_RS04340 (GTHT12_00245) - 858075..858743 (-) 669 WP_008878969.1 TerC family protein -
  GTHT12_RS04345 (GTHT12_00246) mecA 858960..859640 (+) 681 WP_008878968.1 adaptor protein MecA -
  GTHT12_RS04350 (GTHT12_00247) cls 859737..861245 (+) 1509 WP_008878967.1 cardiolipin synthase -
  GTHT12_RS04355 (GTHT12_00248) - 861393..862679 (+) 1287 WP_008878966.1 competence protein CoiA family protein -
  GTHT12_RS04360 (GTHT12_00249) pepF 862712..864535 (+) 1824 WP_011886942.1 oligoendopeptidase F Regulator
  GTHT12_RS04365 - 864549..864746 (-) 198 WP_011886943.1 hypothetical protein -
  GTHT12_RS04370 (GTHT12_00250) spxH 865018..865911 (-) 894 WP_029761532.1 ClpXP adapter protein SpxH -
  GTHT12_RS04375 (GTHT12_00251) - 865904..866317 (-) 414 WP_008878963.1 globin -
  GTHT12_RS04380 (GTHT12_00252) - 866419..867027 (-) 609 WP_029761533.1 lytic transglycosylase domain-containing protein -
  GTHT12_RS04385 (GTHT12_00253) - 867027..867614 (-) 588 WP_008878961.1 CYTH domain-containing protein -
  GTHT12_RS04390 (GTHT12_00254) - 867749..868126 (+) 378 WP_008878960.1 hypothetical protein -
  GTHT12_RS04395 (GTHT12_00255) - 868254..868892 (+) 639 WP_029761535.1 GTP pyrophosphokinase family protein -

Sequence

Protein


Download         Length: 607 a.a.        Molecular weight: 70281.13 Da        Isoelectric Point: 4.9488

>NTDB_id=220520 GTHT12_RS04360 WP_011886942.1 862712..864535(+) (pepF) [Geobacillus thermodenitrificans strain T12]
MTVEENKAKKSLPSRSEIPVEETWRLEDIFPTDDAWEQEFQQVKAMIPKISEYKGRLGESPEVMYEALQYQDEVSMRLGK
LYTYAHMRYDQDTTNSFYQGLDDRAKGLYSEASSAMAFIVPEILAIDEAVLRSFLEQYEPLRLYEHALDEITRQRPHVLS
AEEEALLAQAAEVMQATSSTFSALNNADLTFPTIRDENGDEVEVTHGRFIRFLESTDRRVRRDAFHAVYHTYEKFQNTFA
NTLAGTVKKDNFFARVRRYKSAREAALDANNIPESVYDNLIATIHEHLPLLHRYVRLRKSVLGLDELHMYDLYTPLVQDV
KMEVTYDEAKQYMLDGLAPLGEEYVSIVKEGLENRWVDVRENKGKRSGAYSSGAYGTHPYILLNWQDNVNNLFTLVHEFG
HSVHSYYTRKTQPYPYAHYSIFVAEVASTCNEALLNDYLLKTIDDEKKRLYLLNHYLEGFRGTVFRQTMFAEFEHLIHLK
AQEGEALTAQTLTSLYYDLNKKYFGDDMVVDEEIGLEWARIPHFYYNYYVYQYATGFSAATALSKQILEEGEPAVKRYIE
FLKAGSSDYPIEVLKKAGVDMTSAEPIRQACQVFAEKLEEMERLLGK

Nucleotide


Download         Length: 1824 bp        

>NTDB_id=220520 GTHT12_RS04360 WP_011886942.1 862712..864535(+) (pepF) [Geobacillus thermodenitrificans strain T12]
ATGACGGTGGAAGAGAATAAGGCAAAGAAATCGCTCCCGTCCCGGAGCGAAATCCCTGTCGAGGAAACGTGGCGGCTCGA
GGACATTTTCCCAACCGATGATGCGTGGGAACAGGAGTTTCAGCAAGTAAAGGCGATGATTCCAAAAATCAGCGAATACA
AAGGGCGGCTTGGCGAATCGCCGGAAGTGATGTATGAAGCGCTGCAATACCAAGATGAAGTATCGATGCGTCTCGGCAAG
CTGTATACATACGCCCATATGCGCTATGACCAAGACACGACGAACTCGTTTTACCAAGGGCTCGACGACAGGGCGAAAGG
GTTGTACAGCGAAGCATCGAGCGCGATGGCGTTTATCGTGCCGGAAATTTTAGCCATCGATGAAGCGGTGCTGCGTTCGT
TTTTAGAGCAATACGAACCGCTTCGGCTGTATGAGCACGCGTTAGACGAAATCACGCGCCAGCGCCCGCACGTCTTGTCC
GCTGAAGAAGAAGCGCTGTTGGCACAGGCTGCTGAGGTGATGCAGGCGACATCGTCGACGTTCAGTGCGTTAAACAACGC
TGACTTAACGTTCCCGACGATTCGCGACGAAAATGGGGATGAAGTGGAAGTGACGCACGGCCGGTTTATCCGATTTTTAG
AAAGTACCGACCGCCGCGTTCGTCGCGATGCGTTTCATGCAGTATACCATACGTACGAGAAGTTCCAGAACACGTTTGCC
AACACACTTGCGGGCACGGTGAAAAAAGACAACTTTTTCGCTCGCGTCCGCCGCTACAAATCAGCACGAGAAGCGGCGTT
AGATGCGAACAATATACCGGAAAGCGTCTATGATAATTTAATTGCCACAATTCATGAGCATTTACCGCTTTTGCACCGGT
ATGTGCGGCTGCGCAAAAGCGTACTAGGGCTTGACGAGCTGCATATGTATGACTTATATACTCCGCTCGTGCAAGATGTG
AAAATGGAAGTGACATACGACGAAGCGAAGCAATATATGCTTGACGGGTTGGCGCCGCTTGGCGAGGAATATGTGTCGAT
CGTCAAAGAAGGGCTTGAGAATCGATGGGTCGATGTGCGCGAAAATAAAGGAAAGCGAAGTGGAGCCTATTCGTCAGGAG
CGTATGGCACCCACCCGTATATTTTGCTGAACTGGCAAGATAATGTGAACAACTTGTTTACGCTCGTACATGAGTTCGGC
CACTCAGTCCATAGTTACTATACGCGCAAAACGCAGCCGTATCCGTATGCTCATTATTCGATTTTTGTCGCTGAAGTGGC
GTCGACATGCAATGAGGCATTGCTGAACGATTATTTGTTGAAAACGATCGATGATGAGAAAAAACGGCTATACTTGCTGA
ACCATTATCTTGAAGGATTCCGCGGTACTGTCTTTCGACAAACGATGTTTGCCGAGTTCGAGCATTTGATCCATCTGAAG
GCGCAAGAAGGAGAGGCGCTGACAGCACAGACGCTCACATCGCTCTATTATGATCTGAACAAAAAATATTTCGGTGATGA
TATGGTGGTTGATGAGGAAATTGGTCTTGAATGGGCGCGCATCCCGCATTTTTATTACAACTATTACGTATATCAATACG
CGACCGGCTTCAGCGCAGCAACGGCGCTTAGCAAGCAGATTTTAGAGGAAGGCGAGCCGGCGGTGAAACGGTACATCGAG
TTTTTAAAAGCCGGCAGCTCTGATTATCCGATTGAGGTGCTGAAAAAAGCTGGCGTCGATATGACGAGCGCTGAACCGAT
TCGTCAAGCGTGTCAAGTGTTTGCAGAGAAGTTGGAAGAAATGGAGCGCTTGCTTGGAAAATAA

Domains

Predicted by InterproScan.

Peptidase family M3 (Peptidase_M3)

(213-592)

Oligopeptidase F (Peptidase_M3_N)

(122-191)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A4IL78

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pepF Streptococcus salivarius strain HSISS4

51.01

97.858

0.499

Multiple sequence alignment