Detailed information    

insolico Bioinformatically predicted

Overview

Name   sepM   Type   Regulator
Locus tag   B4W66_RS06300 Genome accession   NZ_CP020027
Coordinates   1222661..1223698 (-) Length   345 a.a.
NCBI ID   WP_076639313.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain STAB090229     
Function   processing of CSP (predicted from homology)   
Competence regulation

Genomic Context

Location: 1217661..1228698
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  B4W66_RS06280 (B4W66_06285) - 1218411..1219037 (+) 627 WP_002983834.1 prepilin peptidase -
  B4W66_RS06285 (B4W66_06290) rlmN 1219119..1220198 (-) 1080 WP_020905325.1 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN -
  B4W66_RS06290 (B4W66_06295) - 1220202..1220822 (-) 621 WP_002992791.1 YutD family protein -
  B4W66_RS06295 (B4W66_06300) - 1221270..1222247 (-) 978 WP_002994809.1 LacI family DNA-binding transcriptional regulator -
  B4W66_RS06300 (B4W66_06305) sepM 1222661..1223698 (-) 1038 WP_076639313.1 SepM family pheromone-processing serine protease Regulator
  B4W66_RS06305 (B4W66_06310) coaD 1223685..1224176 (-) 492 WP_002983821.1 pantetheine-phosphate adenylyltransferase -
  B4W66_RS06310 (B4W66_06315) rsmD 1224166..1224705 (-) 540 WP_002983819.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  B4W66_RS06315 (B4W66_06320) asnA 1224828..1225820 (-) 993 WP_020905328.1 aspartate--ammonia ligase -
  B4W66_RS06320 (B4W66_06325) arcC 1226133..1227083 (-) 951 WP_010922501.1 carbamate kinase -
  B4W66_RS06325 (B4W66_06330) - 1227103..1228434 (-) 1332 WP_011054719.1 dipeptidase -

Sequence

Protein


Download         Length: 345 a.a.        Molecular weight: 37571.27 Da        Isoelectric Point: 9.6692

>NTDB_id=220437 B4W66_RS06300 WP_076639313.1 1222661..1223698(-) (sepM) [Streptococcus pyogenes strain STAB090229]
MKRLKKIKWWLVGLLALISLLLALFFPLPYYIEMPGGAYDIRTVLQVNGKEDKRKGAYQFVAVGISRASLAQLLYAWLTP
FTEISTAEDTTGGYSDADFLRINQFYMETSQNAAIYQALSLAGKPVTLDYKGVYVLDVNNESTFKGTLHLTDTVTGVNGK
QFTSSAELIDYVSHLKLGDEVTVQFTSDNKPKKGVGRIIKLKNGKNGIGIALTDHTSVNSEDTVIFSTKGVGGPSAGLMF
TLDIYDQITKEDLRKGRTIAGTGTIGKDGEVGDIGGAGLKVVAAAEAGADIFFVPNNPVDKEIKKVNPNAISNYEEAKRA
AKRLKTKMKIVPVTTVQEALVYLRK

Nucleotide


Download         Length: 1038 bp        

>NTDB_id=220437 B4W66_RS06300 WP_076639313.1 1222661..1223698(-) (sepM) [Streptococcus pyogenes strain STAB090229]
ATGAAAAGACTTAAAAAAATCAAATGGTGGTTAGTGGGTCTGCTAGCTTTAATCTCTTTGTTGCTAGCGTTATTTTTTCC
GCTACCTTATTATATTGAAATGCCTGGAGGCGCTTACGATATTCGGACTGTCTTACAAGTCAATGGCAAAGAAGACAAAC
GAAAAGGAGCTTACCAGTTTGTTGCAGTGGGCATTAGTCGTGCCAGCCTCGCTCAGCTATTATATGCTTGGCTGACACCG
TTTACTGAAATTAGTACAGCAGAAGATACAACAGGCGGATACAGCGATGCTGATTTCCTTCGAATTAATCAATTTTACAT
GGAAACATCACAAAATGCAGCTATTTATCAAGCTTTATCCTTAGCTGGAAAACCAGTTACATTAGATTATAAAGGCGTAT
ATGTTTTAGATGTAAACAACGAATCTACTTTTAAAGGAACGTTACACTTAACAGATACTGTAACAGGTGTAAATGGTAAA
CAGTTTACTAGTTCAGCAGAACTTATTGACTATGTTTCTCACCTAAAACTAGGGGATGAAGTTACGGTTCAGTTTACGAG
TGATAATAAGCCTAAAAAAGGAGTTGGCCGTATTATCAAACTGAAAAATGGGAAAAATGGGATTGGCATTGCCTTGACTG
ATCATACAAGTGTCAATTCAGAAGACACAGTGATCTTTAGTACTAAAGGAGTAGGAGGACCTAGTGCTGGTCTAATGTTT
ACTCTTGATATATATGATCAAATAACTAAAGAAGATTTACGCAAGGGCCGTACAATTGCAGGTACAGGAACTATTGGCAA
GGATGGCGAAGTAGGAGATATTGGTGGTGCAGGTCTTAAAGTAGTTGCAGCAGCTGAAGCTGGTGCAGATATATTTTTTG
TTCCGAATAATCCTGTTGATAAGGAAATTAAAAAAGTTAATCCAAATGCTATAAGTAATTACGAAGAAGCCAAACGGGCA
GCCAAACGACTAAAGACCAAAATGAAGATTGTTCCTGTTACGACTGTTCAAGAGGCACTGGTTTATCTTCGCAAATAA

Domains

Predicted by InterproScan.

Lon protease (S16) C-terminal proteolytic domain (Lon_C)

(233-309)

PDZ domain (PDZ_2)

(129-192)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sepM Streptococcus mutans UA159

68.986

100

0.69

Multiple sequence alignment