Detailed information NTG0220374

Bioinformatically predicted

Overview

• Name: codY
• Type: Regulator
• Locus tag: BS21228_RS21190
• Genome accession: NZ_CP020023
• Coordinates: 3979783..3980562 (+)
• Length: 259 a.a.
• NCBI ID: WP_003220850.1
• Uniprot ID: G4NSM6
• Organism: Bacillus subtilis strain ATCC 21228
• Function: repression of comK (predicted from homology) Competence regulation

Genomic Context

Location: 3974783..3985562

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BS21228_RS21170 (BS21228_21100)	trmFO	3975476..3976783 (+)	1308	WP_003244725.1	FADH(2)-oxidizing methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))- methyltransferase TrmFO	-
BS21228_RS21175 (BS21228_21105)	xerC	3976851..3977765 (+)	915	WP_014479777.1	tyrosine recombinase XerC	-
BS21228_RS21180 (BS21228_21110)	clpQ	3977778..3978323 (+)	546	WP_003238555.1	ATP-dependent protease subunit ClpQ	-
BS21228_RS21185 (BS21228_21115)	hslU	3978340..3979743 (+)	1404	WP_014476801.1	HslU--HslV peptidase ATPase subunit	-
BS21228_RS21190 (BS21228_21120)	codY	3979783..3980562 (+)	780	WP_003220850.1	GTP-sensing pleiotropic transcriptional regulator CodY	Regulator
BS21228_RS21195 (BS21228_21125)	flgB	3980942..3981331 (+)	390	WP_014479778.1	flagellar basal body rod protein FlgB	-
BS21228_RS21200 (BS21228_21130)	flgC	3981331..3981783 (+)	453	WP_014479779.1	flagellar basal body rod protein FlgC	-
BS21228_RS21205 (BS21228_21135)	fliE	3981794..3982114 (+)	321	WP_003238544.1	flagellar hook-basal body complex protein FliE	-
BS21228_RS21210 (BS21228_21140)	fliF	3982160..3983757 (+)	1598	Protein_4132	flagellar basal-body MS-ring/collar protein FliF	-
BS21228_RS21215 (BS21228_21145)	fliG	3983770..3984786 (+)	1017	WP_003231981.1	flagellar motor switch protein FliG	-
BS21228_RS21220 (BS21228_21150)	fliH	3984779..3985531 (+)	753	WP_014479782.1	flagellar assembly protein FliH	-

Sequence

Protein

• Length: 259 a.a.
• Molecular weight: 29013.22 Da
• Isoelectric Point: 4.6514

>NTDB_id=220374 BS21228_RS21190 WP_003220850.1 3979783..3980562(+) (codY) [Bacillus subtilis strain ATCC 21228]
MALLQKTRIINSMLQAAAGKPVNFKEMAETLRDVIDSNIFVVSRRGKLLGYSINQQIENDRMKKMLEDRQFPEEYTKNLF
NVPETSSNLDINSEYTAFPVENRDLFQAGLTTIVPIIGGGERLGTLILSRLQDQFNDDDLILAEYGATVVGMEILREKAE
EIEEEARSKAVVQMAISSLSYSELEAIEHIFEELDGNEGLLVASKIADRVGITRSVIVNALRKLESAGVIESRSLGMKGT
YIKVLNNKFLIELENLKSH

Nucleotide

• Length: 780 bp

>NTDB_id=220374 BS21228_RS21190 WP_003220850.1 3979783..3980562(+) (codY) [Bacillus subtilis strain ATCC 21228]
ATGGCTTTATTACAAAAAACAAGAATTATTAACTCCATGCTGCAAGCTGCGGCAGGGAAACCGGTAAACTTCAAGGAAAT
GGCGGAGACGCTGCGGGATGTAATTGATTCCAATATTTTCGTTGTAAGCCGCAGAGGGAAACTCCTTGGGTATTCTATTA
ACCAGCAAATTGAAAATGATCGTATGAAAAAAATGCTTGAGGATCGTCAATTCCCTGAAGAATATACGAAAAATCTGTTT
AATGTCCCTGAAACATCTTCTAACTTGGATATTAATAGTGAATATACTGCTTTCCCTGTTGAGAACAGAGACCTGTTTCA
AGCTGGTTTAACAACAATTGTGCCGATCATCGGAGGCGGGGAAAGATTAGGAACACTTATTCTTTCGCGTTTACAAGATC
AATTCAATGACGATGACTTAATTCTAGCTGAATACGGCGCAACAGTTGTCGGAATGGAAATCCTAAGAGAAAAAGCAGAA
GAAATTGAAGAGGAAGCAAGAAGCAAAGCTGTCGTACAAATGGCTATCAGCTCGCTTTCTTACAGTGAGCTTGAAGCAAT
TGAGCACATTTTTGAGGAGCTTGACGGAAATGAAGGTCTTCTTGTTGCAAGTAAAATTGCTGACCGTGTCGGCATTACCC
GTTCTGTTATTGTGAACGCACTCAGAAAGCTGGAGAGCGCCGGTGTTATCGAGTCTAGATCATTAGGAATGAAAGGTACT
TATATCAAGGTACTAAACAACAAATTCTTAATTGAATTAGAAAATCTAAAATCTCATTAA

Domains

Predicted by InterproScan.

• CodY helix-turn-helix domain (HTH_CodY) (198-255)

• CodY GAF-like domain (CodY) (3-178)

3D structure

• AlphaFold DB: G4NSM6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
codY	Bacillus subtilis subsp. subtilis str. 168	100	100	1
codY	Lactococcus lactis subsp. lactis strain DGCC12653	47.451	98.456	0.467