Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   BS21228_RS18600 Genome accession   NZ_CP020023
Coordinates   3500032..3500688 (+) Length   218 a.a.
NCBI ID   WP_014479448.1    Uniprot ID   A0A165B643
Organism   Bacillus subtilis strain ATCC 21228     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 3495032..3505688
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BS21228_RS18575 (BS21228_18510) oppF 3495496..3496413 (+) 918 WP_003245567.1 oligopeptide ABC transporter ATP-binding protein OppF -
  BS21228_RS18580 (BS21228_18515) yjbB 3496521..3497738 (+) 1218 WP_072592593.1 MFS transporter -
  BS21228_RS18585 (BS21228_18520) yjbC 3497902..3498480 (+) 579 WP_003224597.1 GNAT family N-acetyltransferase -
  BS21228_RS18590 (BS21228_18525) spx 3498661..3499056 (+) 396 WP_014476435.1 transcriptional regulator Spx -
  BS21228_RS18595 (BS21228_18530) yjbE 3499099..3499755 (-) 657 WP_014479447.1 TerC family protein -
  BS21228_RS22865 - 3499925..3500065 (+) 141 WP_119122854.1 hypothetical protein -
  BS21228_RS18600 (BS21228_18535) mecA 3500032..3500688 (+) 657 WP_014479448.1 adaptor protein MecA Regulator
  BS21228_RS22870 - 3500683..3500805 (-) 123 WP_003245684.1 hypothetical protein -
  BS21228_RS18605 (BS21228_18540) coiA 3500879..3502000 (+) 1122 WP_235091746.1 competence protein CoiA Machinery gene
  BS21228_RS18610 (BS21228_18545) pepF 3502230..3504059 (+) 1830 WP_173401378.1 oligoendopeptidase F -
  BS21228_RS18615 (BS21228_18550) - 3504097..3504264 (-) 168 WP_003244944.1 hypothetical protein -
  BS21228_RS18625 (BS21228_18560) spxH 3504579..3505478 (-) 900 WP_003245184.1 protease adaptor protein SpxH -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25733.66 Da        Isoelectric Point: 4.1174

>NTDB_id=220365 BS21228_RS18600 WP_014479448.1 3500032..3500688(+) (mecA) [Bacillus subtilis strain ATCC 21228]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHEEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPASEDLDALLDDFQKEEQAVNQEEKEQKLQFVLRFGDFEDVISLSKLNVNGSKTTLYSFENR
YYLYVDFCNMTDEEVENQLSILLEYATESSISIHRLEEYGKLIISEHALEAIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=220365 BS21228_RS18600 WP_014479448.1 3500032..3500688(+) (mecA) [Bacillus subtilis strain ATCC 21228]
ATGGAAATTGAAAGAATTAACGAGCATACAGTAAAATTTTATATGTCTTACGGAGATATTGAAGATCGCGGTTTTGACAG
AGAAGAAATTTGGTATAACCGTGAGCGCAGTGAAGAACTATTCTGGGAAGTCATGGATGAAGTTCATGAAGAAGAGGAAT
TCGCTGTGGAAGGCCCACTTTGGATTCAAGTTCAGGCACTGGACAAAGGATTAGAAATCATCGTCACAAAAGCCCAGCTT
TCCAAAGACGGACAAAAGCTCGAACTGCCGATTCCTGAGGATAAAAAGCAAGAACCAGCATCTGAGGATCTTGACGCCTT
GCTGGATGATTTCCAGAAAGAAGAGCAAGCCGTCAATCAGGAAGAGAAGGAGCAAAAGCTTCAATTTGTCTTGCGATTTG
GCGATTTTGAGGATGTTATTTCTCTATCTAAATTGAACGTTAACGGAAGCAAAACGACTTTATATTCGTTTGAGAACCGA
TATTATTTATATGTAGATTTTTGCAATATGACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGCTGGAGTACGCAAC
TGAATCCTCAATCAGCATACACCGTCTTGAAGAGTACGGCAAGCTGATTATTTCAGAGCATGCTCTAGAAGCGATAAAAA
AACACTTTGCATCATAG

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-211)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A165B643

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

99.541

100

0.995

Multiple sequence alignment