Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   AOZ05_RS11430 Genome accession   NZ_CP019945
Coordinates   2169058..2169774 (+) Length   238 a.a.
NCBI ID   WP_000688498.1    Uniprot ID   Q2VG52
Organism   Staphylococcus aureus strain BA01611     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2164058..2174774
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AOZ05_RS11395 - 2164278..2164904 (+) 627 WP_000522384.1 nitroreductase family protein -
  AOZ05_RS11405 - 2165265..2166050 (+) 786 WP_000867940.1 carbon-nitrogen family hydrolase -
  AOZ05_RS15590 hld 2166647..2166727 (-) 81 WP_000046022.1 delta-hemolysin -
  AOZ05_RS11415 - 2167017..2167580 (+) 564 WP_001105696.1 accessory gene regulator AgrB -
  AOZ05_RS11420 agrD 2167583..2167726 (+) 144 WP_001094921.1 cyclic lactone autoinducer peptide AgrD -
  AOZ05_RS11425 agrC 2167756..2169039 (+) 1284 WP_000447888.1 quorum-sensing sensor histidine kinase AgrC -
  AOZ05_RS11430 agrA 2169058..2169774 (+) 717 WP_000688498.1 quorum-sensing response regulator AgrA Regulator
  AOZ05_RS11435 - 2169854..2169963 (+) 110 Protein_2137 hypothetical protein -
  AOZ05_RS11440 - 2170151..2171110 (-) 960 WP_001253314.1 carbohydrate kinase family protein -
  AOZ05_RS11445 - 2171107..2172591 (-) 1485 WP_000141414.1 sucrose-6-phosphate hydrolase -
  AOZ05_RS11450 - 2172740..2173690 (-) 951 WP_031588340.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27933.91 Da        Isoelectric Point: 6.0927

>NTDB_id=219057 AOZ05_RS11430 WP_000688498.1 2169058..2169774(+) (agrA) [Staphylococcus aureus strain BA01611]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSRDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=219057 AOZ05_RS11430 WP_000688498.1 2169058..2169774(+) (agrA) [Staphylococcus aureus strain BA01611]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGCTTACAATTAT
TATCAAGAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTTAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-237)

Response regulator receiver domain (Response_reg)

(3-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q2VG52

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

99.58

100

0.996

Multiple sequence alignment