Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   CXR04_RS29450 Genome accession   NZ_CP025407
Coordinates   6769542..6770237 (+) Length   231 a.a.
NCBI ID   WP_101425252.1    Uniprot ID   -
Organism   Streptomyces sp. CMB-StM0423     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 6764542..6775237
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CXR04_RS29440 (CXR04_29440) - 6765492..6768068 (+) 2577 WP_234380548.1 FHA domain-containing protein -
  CXR04_RS29445 (CXR04_29445) - 6768383..6769549 (+) 1167 WP_101426674.1 GAF domain-containing sensor histidine kinase -
  CXR04_RS29450 (CXR04_29450) vraR 6769542..6770237 (+) 696 WP_101425252.1 response regulator transcription factor Regulator
  CXR04_RS29455 (CXR04_29455) - 6770404..6770649 (+) 246 WP_101425253.1 chaplin -
  CXR04_RS29460 (CXR04_29460) - 6770861..6771100 (+) 240 WP_199850554.1 chaplin -
  CXR04_RS29465 (CXR04_29465) - 6771241..6772038 (-) 798 WP_101425255.1 hypothetical protein -
  CXR04_RS29470 (CXR04_29470) - 6772154..6772951 (+) 798 WP_101425256.1 ABC transporter ATP-binding protein -
  CXR04_RS29475 (CXR04_29475) - 6773089..6773469 (+) 381 WP_199850680.1 NfeD family protein -
  CXR04_RS29480 (CXR04_29480) - 6773552..6774514 (+) 963 WP_101425258.1 SPFH domain-containing protein -
  CXR04_RS29485 (CXR04_29485) - 6774627..6775154 (-) 528 WP_101425259.1 HNH endonuclease -

Sequence

Protein


Download         Length: 231 a.a.        Molecular weight: 24663.02 Da        Isoelectric Point: 5.4094

>NTDB_id=218797 CXR04_RS29450 WP_101425252.1 6769542..6770237(+) (vraR) [Streptomyces sp. CMB-StM0423]
MAETGEKQRTAGPDETDAPGRIRVLLVDDHQVVRRGLRTFLEVQDDIEVVGEAADGEEGVARTAELVPDVVLMDVKMPGT
DGIEALRRIRESGSAARVLVITSFTEQRTVVPALRAGAAGYVYKDVDPEALAKAIRSVHAGHVLLQQDVAGALLAPEAGG
GPAQGRGTTLTEREREVLALIADGRSNREIARALVVSEKTVKTHVSNILMKLDLADRTQAALWAVRHGLSG

Nucleotide


Download         Length: 696 bp        

>NTDB_id=218797 CXR04_RS29450 WP_101425252.1 6769542..6770237(+) (vraR) [Streptomyces sp. CMB-StM0423]
GTGGCTGAGACGGGCGAGAAGCAGCGGACCGCGGGCCCGGACGAGACGGACGCCCCCGGCCGGATCCGGGTGCTGCTGGT
CGACGACCACCAGGTCGTACGGCGCGGGCTGCGCACCTTCCTGGAGGTGCAGGACGACATCGAGGTCGTCGGCGAGGCCG
CCGACGGCGAGGAGGGCGTGGCCCGTACCGCCGAGCTGGTGCCCGACGTGGTGCTCATGGACGTGAAGATGCCCGGCACC
GACGGCATCGAGGCGCTGCGCCGCATCCGCGAGTCCGGCAGCGCGGCGCGCGTGCTGGTCATCACCAGCTTCACCGAGCA
GCGCACCGTCGTCCCCGCGCTGCGCGCCGGCGCCGCGGGCTACGTCTACAAGGACGTCGACCCCGAGGCGCTGGCCAAGG
CGATCCGCTCGGTGCACGCCGGGCACGTGCTGCTCCAGCAGGACGTCGCCGGGGCGCTGCTGGCGCCGGAGGCCGGCGGC
GGTCCCGCGCAGGGCAGGGGGACGACGCTGACCGAGCGCGAGCGTGAGGTGCTGGCGCTGATCGCGGACGGCCGCTCGAA
CCGGGAGATCGCCCGCGCGCTCGTGGTCTCGGAGAAGACCGTCAAGACGCACGTGTCGAACATCCTGATGAAGCTCGACC
TCGCGGACCGTACACAGGCCGCCCTCTGGGCCGTACGCCACGGCCTGAGCGGCTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(24-136)

Bacterial regulatory proteins, luxR family (GerE)

(169-224)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

44.712

90.043

0.403