Detailed information NTG0218761

Bioinformatically predicted

Overview

• Name: disA
• Type: Machinery gene
• Locus tag: CXR04_RS16235
• Genome accession: NZ_CP025407
• Coordinates: 3768651..3769775 (+)
• Length: 374 a.a.
• NCBI ID: WP_101423058.1
• Uniprot ID: -
• Organism: Streptomyces sp. CMB-StM0423
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 3763651..3774775

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CXR04_RS16215 (CXR04_16215)	-	3763778..3764377 (+)	600	WP_101423050.1	TetR/AcrR family transcriptional regulator	-
CXR04_RS16220 (CXR04_16220)	-	3764409..3764912 (-)	504	WP_101423052.1	hypothetical protein	-
CXR04_RS16225 (CXR04_16225)	ilvD	3765072..3766925 (-)	1854	WP_101423054.1	dihydroxy-acid dehydratase	-
CXR04_RS16230 (CXR04_16230)	radA	3767086..3768540 (+)	1455	WP_101423056.1	DNA repair protein RadA	Machinery gene
CXR04_RS16235 (CXR04_16235)	disA	3768651..3769775 (+)	1125	WP_101423058.1	DNA integrity scanning diadenylate cyclase DisA	Machinery gene
CXR04_RS16240 (CXR04_16240)	-	3769970..3770854 (-)	885	WP_101423060.1	hypothetical protein	-
CXR04_RS16245 (CXR04_16245)	-	3770982..3771560 (+)	579	WP_101423062.1	phosphatase PAP2 family protein	-
CXR04_RS16250 (CXR04_16250)	-	3771634..3773487 (+)	1854	WP_101423064.1	sigma-70 family RNA polymerase sigma factor	-
CXR04_RS16255 (CXR04_16255)	-	3773691..3774509 (-)	819	WP_101426407.1	hypothetical protein	-

Sequence

Protein

• Length: 374 a.a.
• Molecular weight: 40233.95 Da
• Isoelectric Point: 5.2177

>NTDB_id=218761 CXR04_RS16235 WP_101423058.1 3768651..3769775(+) (disA) [Streptomyces sp. CMB-StM0423]
MAAGDRVGAPGRAGGSSGSDAAVRAALSAVAPGTGLRDGLERVLRGNTGGLIVLGTDKIIESICTGGFVLDVEFTATRLR
ELCKLDGAVVLDQDITRIERAGVQLLPDASIPTEETGTRHRTAQRVSIQSGFPVVSVSQSMRLIALYVDGQRRVLEDSAA
ILSRANQALATLERYKLRLDEVAGTLSALEIEDLVTVRDVSAVAQRLEMVRRIATEIAEYVVELGTDGRLLSLQLDELIA
GVEPERQLVVRDYVPERTGRRPHTVERALTELDRLAHGELLELPIVARSLGYSGVPETLDAAVSPRGYRLLAKVPRIPSA
VIDRLVEHFGGLQKLLAASVDDLQTVDGVGEARARSVREGLSRLAESSILERYV

Nucleotide

• Length: 1125 bp

>NTDB_id=218761 CXR04_RS16235 WP_101423058.1 3768651..3769775(+) (disA) [Streptomyces sp. CMB-StM0423]
GTGGCAGCAGGCGACCGGGTGGGCGCCCCGGGCAGAGCCGGCGGCAGTTCCGGCTCCGATGCCGCGGTGAGGGCCGCGCT
GAGCGCGGTCGCGCCCGGCACGGGGCTGCGTGACGGCCTGGAGCGGGTCCTCCGCGGCAACACGGGCGGGCTCATCGTGC
TGGGCACGGACAAGATCATCGAGTCCATCTGCACCGGCGGCTTCGTGCTGGACGTCGAGTTCACCGCGACCCGGCTGCGG
GAGCTGTGCAAGCTCGACGGCGCCGTGGTCCTCGACCAGGACATCACGCGGATCGAGCGCGCGGGCGTGCAGTTGCTGCC
CGACGCCTCGATCCCCACCGAGGAGACGGGCACCCGCCACCGCACCGCGCAGCGGGTGTCGATCCAGAGTGGCTTCCCCG
TCGTCTCCGTCAGCCAGTCGATGCGGCTCATCGCGCTGTACGTCGACGGCCAGCGGCGCGTGCTGGAGGACTCCGCCGCG
ATCCTCTCCCGGGCGAACCAGGCGCTGGCCACCCTGGAGCGGTACAAGCTCCGGCTGGACGAGGTCGCCGGCACGCTCTC
CGCGCTGGAGATCGAGGACCTGGTGACGGTGCGGGACGTCTCCGCCGTCGCGCAGCGGCTGGAGATGGTGCGCCGGATCG
CCACCGAGATCGCGGAGTACGTGGTCGAGCTGGGCACCGACGGCCGGCTGCTGTCCCTCCAGCTCGACGAGCTGATCGCG
GGCGTCGAGCCGGAACGCCAGCTCGTCGTCAGGGACTACGTGCCGGAGCGCACCGGCCGCCGCCCGCACACCGTGGAGCG
CGCGCTCACCGAGCTGGACCGGCTCGCCCACGGCGAGCTGCTCGAACTGCCCATCGTGGCCCGCTCGCTGGGCTATTCCG
GGGTGCCCGAGACCCTGGACGCCGCGGTCTCGCCGCGGGGTTACCGGCTGCTGGCCAAGGTGCCGCGCATCCCCAGCGCC
GTCATCGACCGGCTGGTGGAGCACTTCGGCGGGCTGCAGAAGCTGCTCGCCGCCAGCGTGGACGACCTGCAGACGGTCGA
CGGCGTGGGCGAGGCGCGGGCCCGCTCGGTGCGCGAGGGGCTGTCGCGGCTGGCGGAGTCGTCGATCCTGGAGCGCTACG
TCTGA

Domains

Predicted by InterProScan.

• DisA bacterial checkpoint controller linker region (DisA-linker) (155-295)

• DisA bacterial checkpoint controller nucleotide-binding (DAC) (38-151)

• Helix-hairpin-helix motif (HHH_2) (324-359)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
disA	Bacillus subtilis subsp. subtilis str. 168	45.115	93.048	0.42