Detailed information NTG0218563

Bioinformatically predicted

Overview

• Name: amiE
• Type: Regulator
• Locus tag: CR922_RS02620
• Genome accession: NZ_CP025400
• Coordinates: 489400..490485 (+)
• Length: 361 a.a.
• NCBI ID: WP_011226304.1
• Uniprot ID: Q5M3H6
• Organism: Streptococcus thermophilus strain EPS
• Function: internalize XIP (predicted from homology) Competence regulation

Genomic Context

Location: 484400..495485

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CR922_RS02605	amiA	484942..486909 (+)	1968	WP_011226784.1	peptide ABC transporter substrate-binding protein	Regulator
CR922_RS02610	amiC	486971..488464 (+)	1494	WP_011227407.1	ABC transporter permease	Regulator
CR922_RS02615	amiD	488464..489390 (+)	927	WP_002946409.1	oligopeptide ABC transporter permease OppC	Regulator
CR922_RS02620	amiE	489400..490485 (+)	1086	WP_011226304.1	ABC transporter ATP-binding protein	Regulator
CR922_RS02625	-	490478..491407 (+)	930	WP_002951426.1	ATP-binding cassette domain-containing protein	-
CR922_RS02630	-	491457..492242 (-)	786	WP_002951425.1	hypothetical protein	-
CR922_RS02635	-	492254..492952 (-)	699	WP_011226301.1	ABC transporter ATP-binding protein	-
CR922_RS02640	-	492957..493334 (-)	378	WP_011226300.1	GntR family transcriptional regulator	-
CR922_RS02645	-	493517..494311 (+)	795	WP_059257398.1	HAD hydrolase family protein	-
CR922_RS02650	-	494304..495119 (+)	816	WP_011227405.1	Cof-type HAD-IIB family hydrolase	-

Sequence

Protein

• Length: 361 a.a.
• Molecular weight: 39864.62 Da
• Isoelectric Point: 4.7435

>NTDB_id=218563 CR922_RS02620 WP_011226304.1 489400..490485(+) (amiE) [Streptococcus thermophilus strain EPS]
MTENKNVILSARDIVVEFDVRDRVLTAIRGVSLDLVEGEVLALVGESGSGKSVLTKTFTGMLEENGRVASGSIDYRGKDL
TKFKSHQDWAAIRGAKIATIFQDPMTSLNPIKTIGSQIIEVIVKHQGKTAKEAKKMAIDYMDKVGIPDAEKRFNEYPFQY
SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLKEEYGFSVIFITHDLGVVASIADKVAVMYAGEIIE
YATVEEIFYEPCHPYTWSLLSSLPQLADDNGKLFSIPGTPPSLYTPVVGDAFALRSDYALQIDFEEKAPQFQVSDTHWAK
TWLLHEDAPKVDKPAVIQNLHEKILANMGFAHLGDEEEGNA

Nucleotide

• Length: 1086 bp

>NTDB_id=218563 CR922_RS02620 WP_011226304.1 489400..490485(+) (amiE) [Streptococcus thermophilus strain EPS]
ATGACAGAAAATAAAAATGTAATATTATCGGCTCGCGATATCGTCGTGGAATTTGACGTTCGTGACCGTGTTTTGACAGC
TATTCGAGGGGTTTCTCTTGATTTAGTTGAAGGTGAAGTTTTAGCCTTGGTTGGTGAGTCTGGTTCAGGAAAATCAGTCT
TGACTAAAACTTTTACAGGGATGCTGGAAGAAAATGGTCGTGTAGCTAGCGGATCTATCGACTACCGTGGCAAAGACTTG
ACTAAATTTAAGAGTCACCAAGATTGGGCAGCTATCCGTGGAGCTAAGATTGCAACTATTTTCCAAGATCCAATGACCAG
TCTTAACCCAATTAAGACTATCGGAAGTCAAATTATTGAAGTTATTGTTAAGCACCAAGGGAAAACAGCCAAGGAAGCTA
AAAAAATGGCAATTGATTACATGGACAAGGTTGGTATTCCAGATGCTGAAAAACGTTTCAATGAATATCCTTTCCAATAC
TCTGGTGGGATGCGTCAACGTATCGTTATTGCCATTGCCTTGGCTTGTCGTCCTGATGTCCTTATCTGTGACGAACCAAC
AACTGCCCTTGATGTGACCATTCAAGCTCAAATCATTGACCTCTTGAAATCACTCAAAGAGGAGTATGGTTTCTCGGTCA
TTTTCATTACCCATGACCTTGGCGTCGTAGCAAGTATCGCGGACAAGGTTGCTGTCATGTATGCTGGCGAAATCATTGAA
TACGCAACTGTTGAGGAAATTTTCTATGAGCCTTGTCATCCATACACGTGGAGCTTGCTTTCAAGTCTGCCACAATTGGC
TGATGATAATGGAAAACTCTTCTCAATTCCAGGGACGCCACCATCACTTTATACACCAGTTGTTGGGGATGCCTTTGCCT
TGCGTTCAGATTATGCTTTGCAGATTGATTTTGAGGAAAAAGCACCACAATTCCAAGTTTCAGATACTCACTGGGCTAAG
ACCTGGCTCTTACATGAGGATGCGCCAAAAGTTGATAAACCTGCGGTTATCCAAAATCTACATGAAAAAATCCTAGCCAA
TATGGGATTTGCACATTTAGGAGATGAGGAGGAAGGCAATGCCTGA

Domains

Predicted by InterProScan.

• ABC transporter (ABC_tran) (29-187)

• Oligopeptide/dipeptide transporter, C-terminal region (oligo_HPY) (239-300)

3D structure

• AlphaFold DB: Q5M3H6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
amiE	Streptococcus thermophilus LMG 18311	100	100	1
amiE	Streptococcus thermophilus LMD-9	100	100	1
amiE	Streptococcus salivarius strain HSISS4	96.953	100	0.97
oppD	Streptococcus mutans UA159	54.441	96.676	0.526