Detailed information    

insolico Bioinformatically predicted

Overview

Name   waaF   Type   Regulator
Locus tag   B1780_RS04185 Genome accession   NZ_CP019838
Coordinates   823185..824138 (+) Length   317 a.a.
NCBI ID   WP_002839071.1    Uniprot ID   A0A5Z1EHW0
Organism   Campylobacter jejuni subsp. jejuni strain ATCC 33560     
Function   repress natural transformation (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 804571..828962 823185..824138 within 0


Gene organization within MGE regions


Location: 804571..828962
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  B1780_RS04095 (B1780_04140) pglI 804571..805500 (-) 930 WP_002882940.1 GalNAc(5)-diNAcBac-PP-undecaprenol beta-1,3-glucosyltransferase -
  B1780_RS04100 (B1780_04145) pglH 805493..806572 (-) 1080 WP_079460667.1 GalNAc-alpha-(1->4)-GalNAc-alpha-(1->3)- diNAcBac-PP-undecaprenol alpha-1,4-N-acetyl-D-galactosaminyltransferase -
  B1780_RS04105 (B1780_04150) pglK 806569..808263 (-) 1695 WP_002883263.1 ABC-type lipopolysaccharide transporter PglK -
  B1780_RS04110 (B1780_04155) galE 808257..809243 (-) 987 WP_002883265.1 UDP-glucose 4-epimerase GalE -
  B1780_RS04115 (B1780_04160) - 809301..810095 (-) 795 WP_002883266.1 3'-5' exonuclease -
  B1780_RS04120 (B1780_04165) waaC 810161..811189 (+) 1029 WP_002883267.1 lipopolysaccharide heptosyltransferase I -
  B1780_RS04125 (B1780_04170) htrB 811179..812066 (+) 888 WP_002883268.1 lipid A biosynthesis lauroyl acyltransferase HtrB -
  B1780_RS04130 (B1780_04175) - 812063..813610 (+) 1548 WP_002883269.1 glycosyltransferase family 2 protein -
  B1780_RS04135 (B1780_04180) - 813614..814786 (+) 1173 WP_052802058.1 glycosyltransferase family 2 protein -
  B1780_RS04140 (B1780_04185) - 814830..815890 (+) 1061 Protein_807 beta-1,4-N-acetylgalactosaminyltransferase -
  B1780_RS04145 - 815862..816757 (-) 896 Protein_808 glycosyltransferase family 2 protein -
  B1780_RS04150 (B1780_04200) - 816846..817722 (+) 877 Protein_809 alpha-2,3-sialyltransferase -
  B1780_RS04155 (B1780_04205) neuB 817723..818763 (+) 1041 WP_002882963.1 N-acetylneuraminate synthase -
  B1780_RS04160 (B1780_04210) neuC 818760..819884 (+) 1125 WP_002882962.1 UDP-N-acetylglucosamine 2-epimerase -
  B1780_RS04165 (B1780_04215) - 819877..820824 (+) 948 WP_002882960.1 glycosyltransferase -
  B1780_RS04170 (B1780_04220) - 820821..821486 (+) 666 WP_002869017.1 cytidylyltransferase domain-containing protein -
  B1780_RS04175 (B1780_04225) - 821474..822307 (+) 834 WP_002882959.1 CatB-related O-acetyltransferase -
  B1780_RS04180 (B1780_04230) - 822299..823126 (-) 828 WP_002869015.1 glycosyltransferase family 2 protein -
  B1780_RS04185 (B1780_04235) waaF 823185..824138 (+) 954 WP_002839071.1 glycosyltransferase family 9 protein Regulator
  B1780_RS04190 (B1780_04240) - 824145..824900 (-) 756 WP_002869013.1 glycosyltransferase family 25 protein -
  B1780_RS04195 (B1780_04245) gmhA 824900..825460 (-) 561 WP_002869012.1 D-sedoheptulose 7-phosphate isomerase -
  B1780_RS04200 (B1780_04250) rfaE1 825457..826842 (-) 1386 WP_002882955.1 D-glycero-beta-D-manno-heptose-7-phosphate kinase -
  B1780_RS04205 (B1780_04255) rfaD 826835..827788 (-) 954 WP_002882954.1 ADP-glyceromanno-heptose 6-epimerase -
  B1780_RS04210 (B1780_04260) gmhB 827789..828349 (-) 561 WP_002882953.1 D-glycero-alpha-D-manno-heptose-1,7-bisphosphate 7-phosphatase -
  B1780_RS04215 (B1780_04265) - 828431..828733 (+) 303 WP_002852762.1 c-type cytochrome -
  B1780_RS04220 (B1780_04270) ccoS 828756..828962 (-) 207 WP_002852798.1 cbb3-type cytochrome oxidase assembly protein CcoS -

Sequence

Protein


Download         Length: 317 a.a.        Molecular weight: 36557.15 Da        Isoelectric Point: 10.2875

>NTDB_id=218444 B1780_RS04185 WP_002839071.1 823185..824138(+) (waaF) [Campylobacter jejuni subsp. jejuni strain ATCC 33560]
MKIFIHLPTWLGDAVMASPALYAIKEHFKNAQFILYGSLVSTALFKEFPNSKIIIENKQSRYKQALSLRKELGKIDFSFA
FRSAFSSKIILHILKTKQRYFFDKNKHKEEHQVLKYLYFIENSLSIKAHFKDLKLPFKLKFQNPLVLKNGKKILGLNPGA
SFGSAKRWDVSYFAKVALNFSQSHEILIFGAGKAEQELCNEIYQILKEQNIKVKNLCNKTTIKTLCQNIAFCDLFITNDS
GPMHISAVYKVKTVAIFGPTKFTQTSPWQNENARWVHLNLACMPCMQKTCPLKHHKCMKDLKPEIIIEVSKQLLFLN

Nucleotide


Download         Length: 954 bp        

>NTDB_id=218444 B1780_RS04185 WP_002839071.1 823185..824138(+) (waaF) [Campylobacter jejuni subsp. jejuni strain ATCC 33560]
ATGAAAATTTTTATACATCTTCCCACTTGGCTAGGCGATGCAGTGATGGCTTCGCCTGCTTTATACGCTATAAAAGAACA
TTTTAAAAATGCCCAATTTATCCTTTATGGCTCTTTGGTTTCCACAGCACTTTTTAAAGAATTTCCTAATTCTAAAATCA
TCATAGAAAATAAACAATCTCGCTATAAACAAGCCCTATCTTTACGCAAAGAACTTGGCAAAATCGATTTTAGCTTTGCT
TTTAGGTCTGCGTTTTCTTCTAAGATTATCTTGCATATTCTTAAAACGAAACAAAGATATTTTTTTGACAAAAACAAGCA
CAAAGAAGAACATCAAGTTTTAAAATACCTTTATTTTATAGAAAACTCACTTAGTATAAAAGCTCATTTTAAAGACTTAA
AGCTTCCCTTTAAGCTAAAATTTCAAAACCCTCTTGTCTTAAAAAATGGTAAAAAAATTCTAGGACTCAACCCTGGTGCA
AGCTTTGGAAGTGCAAAAAGATGGGATGTGAGTTATTTTGCTAAAGTGGCTTTAAATTTCAGCCAAAGTCATGAGATTTT
AATCTTTGGTGCAGGAAAAGCCGAACAAGAACTTTGTAATGAAATTTATCAAATTTTAAAAGAACAAAACATAAAAGTAA
AAAATCTTTGCAATAAAACTACCATCAAAACCCTTTGTCAAAATATCGCTTTTTGCGATCTTTTCATCACAAATGACAGT
GGACCTATGCACATAAGTGCGGTTTATAAGGTAAAAACCGTGGCTATTTTTGGCCCTACGAAATTTACTCAAACTTCACC
TTGGCAAAATGAAAATGCAAGATGGGTGCATTTAAATCTAGCTTGTATGCCTTGTATGCAAAAAACCTGCCCTTTAAAAC
ACCACAAATGCATGAAAGATTTAAAACCAGAAATCATCATAGAAGTAAGTAAACAATTGCTATTTCTAAATTAA

Domains

Predicted by InterproScan.

Glycosyltransferase family 9 (heptosyltransferase) (Glyco_transf_9)

(96-294)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A5Z1EHW0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  waaF Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

93.631

99.054

0.927

Multiple sequence alignment