Detailed information    

insolico Bioinformatically predicted

Overview

Name   pepF   Type   Regulator
Locus tag   AZI10_RS05190 Genome accession   NZ_CP019750
Coordinates   1025980..1027785 (+) Length   601 a.a.
NCBI ID   WP_085763094.1    Uniprot ID   -
Organism   Levilactobacillus brevis strain TMW 1.2113     
Function   degradation of XIP; competence shut-off (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 1018109..1055550 1025980..1027785 within 0


Gene organization within MGE regions


Location: 1018109..1055550
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AZI10_RS05145 (AZI10_05150) - 1018109..1019083 (+) 975 WP_015473919.1 3'-5' exoribonuclease YhaM family protein -
  AZI10_RS05150 (AZI10_05155) - 1019148..1020065 (-) 918 WP_011668209.1 peptidylprolyl isomerase PrsA -
  AZI10_RS05155 (AZI10_05160) - 1020178..1020498 (-) 321 WP_085763090.1 hypothetical protein -
  AZI10_RS05160 (AZI10_05165) - 1020501..1020959 (-) 459 WP_176552875.1 HIT family protein -
  AZI10_RS05165 (AZI10_05170) - 1021169..1021903 (+) 735 WP_085763091.1 ABC transporter ATP-binding protein -
  AZI10_RS05170 (AZI10_05175) - 1021900..1023126 (+) 1227 WP_085763092.1 ABC transporter permease -
  AZI10_RS05175 (AZI10_05180) - 1023188..1023979 (+) 792 WP_043022830.1 phosphotransferase family protein -
  AZI10_RS05180 (AZI10_05185) trmB 1024045..1024692 (+) 648 WP_043022829.1 tRNA (guanosine(46)-N7)-methyltransferase TrmB -
  AZI10_RS05185 (AZI10_05190) - 1024819..1025913 (+) 1095 WP_085763093.1 competence protein CoiA -
  AZI10_RS05190 (AZI10_05195) pepF 1025980..1027785 (+) 1806 WP_085763094.1 oligoendopeptidase F Regulator
  AZI10_RS05195 (AZI10_05200) - 1027839..1028702 (-) 864 WP_011668200.1 DegV family protein -
  AZI10_RS05200 (AZI10_05205) - 1028980..1029618 (-) 639 WP_043022825.1 ClpXP adapter SpxH family protein -
  AZI10_RS05205 (AZI10_05210) - 1029945..1030604 (+) 660 WP_011668198.1 GTP pyrophosphokinase family protein -
  AZI10_RS05210 (AZI10_05215) - 1030606..1031409 (+) 804 WP_021740943.1 NAD kinase -
  AZI10_RS05215 (AZI10_05220) - 1031406..1032305 (+) 900 WP_011668196.1 RluA family pseudouridine synthase -
  AZI10_RS05220 (AZI10_05225) - 1032765..1034231 (+) 1467 WP_085763095.1 KxYKxGKxW signal peptide domain-containing protein -
  AZI10_RS05225 (AZI10_05230) - 1034388..1040750 (+) 6363 WP_085763096.1 LPXTG cell wall anchor domain-containing protein -
  AZI10_RS05230 (AZI10_05235) - 1041112..1042611 (+) 1500 WP_043022824.1 glycosyltransferase -
  AZI10_RS05235 (AZI10_05240) - 1042639..1044156 (+) 1518 WP_085763097.1 glycosyltransferase -
  AZI10_RS05240 (AZI10_05245) - 1044236..1044481 (+) 246 WP_043022822.1 hypothetical protein -
  AZI10_RS05245 (AZI10_05250) - 1044542..1046110 (+) 1569 WP_225395631.1 glycosyltransferase -
  AZI10_RS05250 (AZI10_05255) - 1046145..1046705 (+) 561 WP_085763098.1 hypothetical protein -
  AZI10_RS05255 (AZI10_05260) - 1046687..1047034 (+) 348 WP_085763099.1 hypothetical protein -
  AZI10_RS14110 (AZI10_05265) - 1047099..1047941 (-) 843 WP_191981941.1 CatB-related O-acetyltransferase -
  AZI10_RS05265 (AZI10_05270) - 1048226..1049056 (+) 831 WP_191981942.1 CatB-related O-acetyltransferase -
  AZI10_RS05270 (AZI10_05275) - 1049459..1050970 (+) 1512 WP_085763100.1 glycosyltransferase -
  AZI10_RS05275 (AZI10_05280) asp1 1051041..1052555 (+) 1515 WP_085763101.1 accessory Sec system glycosyltransferase Asp1 -
  AZI10_RS05280 (AZI10_05285) - 1052586..1054127 (+) 1542 WP_085763102.1 glycosyltransferase -
  AZI10_RS05285 (AZI10_05290) - 1054627..1055550 (+) 924 WP_024526065.1 IS30 family transposase -

Sequence

Protein


Download         Length: 601 a.a.        Molecular weight: 67189.19 Da        Isoelectric Point: 4.8201

>NTDB_id=218233 AZI10_RS05190 WP_085763094.1 1025980..1027785(+) (pepF) [Levilactobacillus brevis strain TMW 1.2113]
MKQIPKRSEVPTSLTWDLTTIFPDEAAFKAAIAAIKTQTTVVAGLKGQLAQSGAALYRVTTAVFDLNRQLERVYVYASLN
NDQDTGNAAAQALMGQAESLVATVGAATAWFEPEVLALSADQLQTLIDNEPRLADYQHVFDVLGQQRAHTLSVAQEKLLA
GASDIFGASAKTYSVLSDADLKFPVVQDEAGNDVRLSEGLYGVLLQSTTPRVRQQAFEALYSVYQQFRHTFAATLASEVK
THNFSAETRHYASARAAAMSRNNVPAVVYDTLVETVNNHLDSLHRYVNLRKEILDLPQLHMYDLYTPITGEPSLKYTYQE
AQEMALKALAVLGPDYTANVQKMFDGRAIDVVENQGKRTGAYSGGMYDTKPYILLNWQDSLESLFTLVHEMGHSMHSHYT
RTNQPYQYGDYSIFVAEIASTTNENLLTDYLLKTQTDPKVRAYVLNHYLDGFKGTVYRQTQFAEFEDYIHQQDAAGETLT
ADFMSDFYGKLNQRYYGDGVISDPQIADEWTRIPHFYYDYYVYQYATGFAAATTLSQRILSGDEAKRDAYLAYLKAGSSA
LPLDVMKQAGVDMTQPGYLQTAFATFDERLAEFTQLAYELN

Nucleotide


Download         Length: 1806 bp        

>NTDB_id=218233 AZI10_RS05190 WP_085763094.1 1025980..1027785(+) (pepF) [Levilactobacillus brevis strain TMW 1.2113]
GTGAAACAAATTCCGAAACGATCAGAGGTTCCCACATCATTGACTTGGGACCTAACAACTATTTTTCCTGACGAGGCAGC
TTTTAAGGCCGCAATTGCTGCGATTAAAACGCAAACAACGGTCGTGGCCGGTTTGAAGGGACAATTGGCCCAAAGTGGGG
CCGCGTTATATCGTGTCACGACGGCGGTATTTGATTTGAATCGCCAGTTGGAGCGGGTATACGTCTATGCGTCTTTAAAC
AATGATCAGGATACCGGCAATGCTGCAGCCCAAGCATTAATGGGGCAAGCCGAGAGTTTGGTGGCAACTGTGGGTGCGGC
CACGGCTTGGTTTGAACCTGAGGTATTGGCCTTGTCAGCGGATCAGCTGCAAACGTTGATTGATAACGAACCCCGGCTGG
CAGATTATCAGCATGTGTTTGACGTATTGGGCCAGCAGCGGGCACATACGCTGTCAGTGGCGCAAGAAAAATTGTTAGCG
GGTGCTAGTGATATCTTTGGTGCGTCTGCTAAAACTTACAGCGTGCTGAGTGATGCTGATCTAAAGTTTCCAGTTGTTCA
AGACGAAGCCGGCAATGATGTGCGACTGTCAGAGGGACTGTATGGTGTTTTGCTACAATCCACAACACCACGGGTGCGGC
AGCAGGCCTTTGAAGCATTATATTCGGTTTATCAACAATTCCGACATACCTTTGCCGCAACCTTAGCGAGCGAAGTCAAA
ACGCATAATTTTAGCGCTGAGACGCGTCACTATGCGAGTGCCAGAGCGGCCGCGATGAGTCGCAACAATGTGCCAGCGGT
GGTCTATGATACCCTGGTGGAAACAGTCAATAATCATTTAGACTCACTGCATCGCTATGTTAATTTGCGCAAAGAGATTT
TGGACTTGCCGCAACTGCACATGTACGACCTGTATACGCCAATTACGGGTGAACCCAGCTTGAAATATACCTACCAAGAA
GCACAAGAGATGGCGTTAAAGGCACTAGCAGTCTTGGGACCGGATTACACTGCCAATGTTCAAAAGATGTTTGATGGCCG
GGCAATTGATGTGGTTGAAAATCAGGGTAAACGGACGGGCGCTTACTCAGGCGGGATGTATGATACTAAACCGTATATTT
TGTTGAATTGGCAAGATAGCTTGGAAAGCTTGTTCACGTTGGTTCATGAGATGGGACACAGCATGCATAGCCATTACACT
CGGACAAATCAACCGTACCAGTATGGTGATTATTCAATCTTTGTTGCGGAAATTGCCTCGACAACGAATGAAAACTTGCT
GACGGACTACCTGTTGAAAACCCAGACTGACCCCAAGGTGCGAGCTTATGTATTAAACCATTATCTGGATGGCTTTAAAG
GCACGGTATACCGCCAGACGCAGTTCGCAGAATTTGAGGACTACATTCACCAACAGGATGCCGCTGGCGAAACTCTGACG
GCTGACTTCATGAGTGATTTCTACGGCAAACTTAATCAGCGTTATTACGGTGATGGGGTGATTTCCGATCCACAAATCGC
TGATGAATGGACCCGAATTCCACATTTCTACTATGACTACTATGTGTACCAGTACGCAACCGGGTTTGCGGCGGCTACGA
CGTTATCGCAACGAATTTTGAGTGGCGACGAGGCAAAGCGGGATGCCTACTTGGCCTATCTAAAGGCGGGAAGTTCTGCC
TTACCACTTGATGTGATGAAACAAGCGGGCGTCGATATGACGCAACCGGGCTATTTGCAGACGGCTTTTGCAACGTTCGA
CGAGCGCTTGGCAGAATTCACGCAATTGGCGTATGAATTAAACTAA

Domains

Predicted by InterproScan.

Peptidase family M3 (Peptidase_M3)

(204-584)

Oligopeptidase F (Peptidase_M3_N)

(114-183)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pepF Streptococcus salivarius strain HSISS4

50

98.17

0.491

Multiple sequence alignment