Detailed information NTG0217586

Bioinformatically predicted

Overview

• Name: amiE
• Type: Regulator
• Locus tag: CW339_RS06955
• Genome accession: NZ_CP025216
• Coordinates: 1311120..1312205 (-)
• Length: 361 a.a.
• NCBI ID: WP_011226304.1
• Uniprot ID: Q5M3H6
• Organism: Streptococcus thermophilus strain DGCC 7710
• Function: internalize XIP (predicted from homology) Competence regulation

Genomic Context

Location: 1306120..1317205

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CW339_RS06925 (CW339_06925)	-	1306484..1307299 (-)	816	WP_011226298.1	Cof-type HAD-IIB family hydrolase	-
CW339_RS06930 (CW339_06930)	-	1307292..1308086 (-)	795	WP_011681412.1	HAD family hydrolase	-
CW339_RS06935 (CW339_06935)	-	1308271..1308648 (+)	378	WP_011681413.1	GntR family transcriptional regulator	-
CW339_RS06940 (CW339_06940)	-	1308653..1309351 (+)	699	WP_023909821.1	ABC transporter ATP-binding protein	-
CW339_RS06945 (CW339_06945)	-	1309363..1310148 (+)	786	WP_002951425.1	hypothetical protein	-
CW339_RS06950 (CW339_06950)	-	1310198..1311127 (-)	930	WP_002951426.1	ATP-binding cassette domain-containing protein	-
CW339_RS06955 (CW339_06955)	amiE	1311120..1312205 (-)	1086	WP_011226304.1	ABC transporter ATP-binding protein	Regulator
CW339_RS06960 (CW339_06960)	amiD	1312215..1313141 (-)	927	WP_002946409.1	oligopeptide ABC transporter permease OppC	Regulator
CW339_RS06965 (CW339_06965)	amiC	1313141..1314634 (-)	1494	WP_011681416.1	ABC transporter permease	Regulator
CW339_RS06970 (CW339_06970)	amiA	1314696..1316663 (-)	1968	WP_024703940.1	peptide ABC transporter substrate-binding protein	Regulator

Sequence

Protein

• Length: 361 a.a.
• Molecular weight: 39864.62 Da
• Isoelectric Point: 4.7435

>NTDB_id=217586 CW339_RS06955 WP_011226304.1 1311120..1312205(-) (amiE) [Streptococcus thermophilus strain DGCC 7710]
MTENKNVILSARDIVVEFDVRDRVLTAIRGVSLDLVEGEVLALVGESGSGKSVLTKTFTGMLEENGRVASGSIDYRGKDL
TKFKSHQDWAAIRGAKIATIFQDPMTSLNPIKTIGSQIIEVIVKHQGKTAKEAKKMAIDYMDKVGIPDAEKRFNEYPFQY
SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLKEEYGFSVIFITHDLGVVASIADKVAVMYAGEIIE
YATVEEIFYEPCHPYTWSLLSSLPQLADDNGKLFSIPGTPPSLYTPVVGDAFALRSDYALQIDFEEKAPQFQVSDTHWAK
TWLLHEDAPKVDKPAVIQNLHEKILANMGFAHLGDEEEGNA

Nucleotide

• Length: 1086 bp

>NTDB_id=217586 CW339_RS06955 WP_011226304.1 1311120..1312205(-) (amiE) [Streptococcus thermophilus strain DGCC 7710]
ATGACAGAAAATAAAAATGTAATATTATCGGCTCGCGATATCGTCGTGGAATTTGACGTTCGTGACCGTGTTTTGACAGC
TATTCGAGGGGTTTCTCTTGATTTAGTTGAAGGTGAAGTTTTAGCCTTGGTTGGTGAGTCTGGTTCAGGAAAATCAGTCT
TGACTAAAACTTTTACAGGGATGCTGGAAGAAAATGGTCGTGTAGCTAGCGGATCTATCGACTACCGTGGCAAAGACTTG
ACTAAATTTAAGAGTCACCAAGATTGGGCAGCTATCCGTGGAGCTAAGATTGCAACTATTTTCCAAGATCCAATGACCAG
TCTTAACCCAATTAAGACTATCGGAAGTCAAATTATTGAAGTTATTGTTAAGCACCAAGGGAAAACAGCCAAGGAAGCTA
AAAAAATGGCAATTGATTACATGGACAAGGTTGGTATTCCAGATGCTGAAAAACGTTTCAATGAATATCCTTTCCAATAC
TCTGGTGGGATGCGTCAACGTATCGTTATTGCCATTGCCTTGGCTTGTCGTCCTGATGTCCTTATCTGTGACGAACCAAC
AACTGCCCTTGATGTGACCATTCAAGCTCAAATCATTGACCTCTTGAAATCACTCAAAGAGGAGTATGGTTTCTCGGTCA
TTTTCATTACCCATGACCTTGGCGTCGTAGCAAGTATCGCGGACAAGGTTGCTGTCATGTATGCTGGCGAAATCATTGAA
TACGCAACTGTTGAGGAAATTTTCTATGAGCCTTGTCATCCATACACGTGGAGCTTGCTTTCAAGTCTGCCACAATTGGC
TGATGATAATGGAAAACTCTTCTCAATTCCAGGGACGCCACCATCACTTTATACACCAGTTGTTGGGGATGCCTTTGCCT
TGCGTTCAGATTATGCTTTGCAGATTGATTTTGAGGAAAAAGCACCACAATTCCAAGTTTCAGATACTCACTGGGCTAAG
ACCTGGCTCTTACATGAGGATGCGCCAAAAGTTGATAAACCTGCGGTTATCCAAAATCTACATGAAAAAATCCTAGCCAA
TATGGGATTTGCACATTTAGGAGATGAGGAGGAAGGCAATGCCTGA

Domains

Predicted by InterProScan.

• ABC transporter (ABC_tran) (29-187)

• Oligopeptide/dipeptide transporter, C-terminal region (oligo_HPY) (239-300)

3D structure

• AlphaFold DB: Q5M3H6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
amiE	Streptococcus thermophilus LMG 18311	100	100	1
amiE	Streptococcus thermophilus LMD-9	100	100	1
amiE	Streptococcus salivarius strain HSISS4	96.953	100	0.97
oppD	Streptococcus mutans UA159	54.441	96.676	0.526