Detailed information NTG0216765

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: BZK09_RS13785
• Genome accession: NZ_CP019595
• Coordinates: 2685189..2686076 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus strain GD1677
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2680189..2691076

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BZK09_RS13750 (BZK09_13945)	-	2680198..2680290 (+)	93	WP_031774855.1	hypothetical protein	-
BZK09_RS13755 (BZK09_13950)	-	2680398..2680895 (-)	498	WP_001065267.1	glutathione peroxidase	-
BZK09_RS13760 (BZK09_13955)	-	2680905..2681165 (-)	261	WP_014937088.1	hypothetical protein	-
BZK09_RS13770 (BZK09_13965)	-	2681547..2681660 (-)	114	WP_014937089.1	hypothetical protein	-
BZK09_RS13775 (BZK09_13970)	-	2682329..2684329 (-)	2001	WP_000776741.1	ABC transporter permease	-
BZK09_RS13780 (BZK09_13975)	-	2684326..2685081 (-)	756	WP_000923768.1	ABC transporter ATP-binding protein	-
BZK09_RS13785 (BZK09_13980)	braS	2685189..2686076 (-)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
BZK09_RS13790 (BZK09_13985)	braR	2686087..2686752 (-)	666	WP_000697873.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
BZK09_RS13795 (BZK09_13990)	-	2686778..2686978 (-)	201	WP_000604731.1	hypothetical protein	-
BZK09_RS13800 (BZK09_13995)	-	2687176..2688600 (+)	1425	WP_000953736.1	alkaline phosphatase	-
BZK09_RS14275	-	2688670..2688780 (+)	111	WP_001791296.1	hypothetical protein	-
BZK09_RS13810 (BZK09_14005)	-	2688883..2689338 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
BZK09_RS13815 (BZK09_14010)	-	2689582..2690343 (-)	762	WP_000323448.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=216765 BZK09_RS13785 WP_000143420.1 2685189..2686076(-) (braS) [Staphylococcus aureus strain GD1677]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=216765 BZK09_RS13785 WP_000143420.1 2685189..2686076(-) (braS) [Staphylococcus aureus strain GD1677]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTTATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGGCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993