Detailed information NTG0216677

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: BZK07_RS13830
• Genome accession: NZ_CP019593
• Coordinates: 2673243..2674130 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus strain GD705
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2668243..2679130

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BZK07_RS13795 (BZK07_14170)	-	2668252..2668344 (+)	93	WP_031774855.1	hypothetical protein	-
BZK07_RS13800 (BZK07_14175)	-	2668452..2668949 (-)	498	WP_001065267.1	glutathione peroxidase	-
BZK07_RS13805 (BZK07_14180)	-	2668959..2669219 (-)	261	WP_014937088.1	hypothetical protein	-
BZK07_RS13815 (BZK07_14190)	-	2669601..2669714 (-)	114	WP_014937089.1	hypothetical protein	-
BZK07_RS13820 (BZK07_14195)	-	2670383..2672383 (-)	2001	WP_000776741.1	ABC transporter permease	-
BZK07_RS13825 (BZK07_14200)	-	2672380..2673135 (-)	756	WP_000923768.1	ABC transporter ATP-binding protein	-
BZK07_RS13830 (BZK07_14205)	braS	2673243..2674130 (-)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
BZK07_RS13835 (BZK07_14210)	braR	2674141..2674806 (-)	666	WP_000697873.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
BZK07_RS13840 (BZK07_14215)	-	2674832..2675032 (-)	201	WP_000604731.1	hypothetical protein	-
BZK07_RS13845 (BZK07_14220)	-	2675230..2676654 (+)	1425	WP_084570152.1	alkaline phosphatase	-
BZK07_RS14375	-	2676724..2676834 (+)	111	WP_001791296.1	hypothetical protein	-
BZK07_RS13855 (BZK07_14230)	-	2676937..2677392 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
BZK07_RS13860 (BZK07_14235)	-	2677636..2678397 (-)	762	WP_000323448.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=216677 BZK07_RS13830 WP_000143420.1 2673243..2674130(-) (braS) [Staphylococcus aureus strain GD705]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=216677 BZK07_RS13830 WP_000143420.1 2673243..2674130(-) (braS) [Staphylococcus aureus strain GD705]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTTATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGGCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993