Detailed information NTG0216671

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: BZK07_RS09760
• Genome accession: NZ_CP019593
• Coordinates: 1924012..1925055 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain GD705
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1919012..1930055

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BZK07_RS09730 (BZK07_10075)	-	1919433..1920689 (-)	1257	WP_001793428.1	aminopeptidase	-
BZK07_RS09735 (BZK07_10080)	-	1920692..1920892 (-)	201	WP_000180460.1	DUF1128 family protein	-
BZK07_RS09740 (BZK07_10085)	-	1921039..1921503 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
BZK07_RS09745 (BZK07_10090)	-	1921510..1921785 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
BZK07_RS09750 (BZK07_10095)	-	1922063..1923280 (+)	1218	WP_000037081.1	YihY/virulence factor BrkB family protein	-
BZK07_RS09755 (BZK07_10100)	vraR	1923393..1924022 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
BZK07_RS09760 (BZK07_10105)	vraS	1924012..1925055 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
BZK07_RS09765 (BZK07_10110)	liaF	1925052..1925753 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
BZK07_RS09770 (BZK07_10115)	-	1925768..1926154 (-)	387	WP_001110182.1	hypothetical protein	-
BZK07_RS09775 (BZK07_10120)	map	1926371..1927129 (-)	759	WP_000636145.1	type I methionyl aminopeptidase	-
BZK07_RS09785 (BZK07_10135)	-	1927713..1928699 (+)	987	WP_000999712.1	aromatic acid exporter family protein	-
BZK07_RS09790 (BZK07_10140)	-	1928888..1929301 (-)	414	WP_025174370.1	hypothetical protein	-
BZK07_RS09795 (BZK07_10145)	-	1929330..1929440 (-)	111	WP_014937049.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=216671 BZK07_RS09760 WP_001017131.1 1924012..1925055(-) (vraS) [Staphylococcus aureus strain GD705]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=216671 BZK07_RS09760 WP_001017131.1 1924012..1925055(-) (vraS) [Staphylococcus aureus strain GD705]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTTCTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAATTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAATTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGCTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1