Detailed information NTG0216660

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: CWI26_RS11575
• Genome accession: NZ_CP025043
• Coordinates: 2334840..2337380 (-)
• Length: 846 a.a.
• NCBI ID: WP_100881825.1
• Uniprot ID: -
• Organism: Streptococcus suis strain AH681
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 2329840..2342380

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CWI26_RS11545 (CWI26_11545)	-	2330215..2330658 (-)	444	WP_100881819.1	LytTR family DNA-binding domain-containing protein	-
CWI26_RS11550 (CWI26_11550)	-	2330780..2331433 (-)	654	WP_100881820.1	DUF998 domain-containing protein	-
CWI26_RS11555 (CWI26_11555)	-	2331445..2332788 (-)	1344	WP_100881821.1	dihydrolipoyl dehydrogenase family protein	-
CWI26_RS11560 (CWI26_11560)	-	2332801..2333481 (-)	681	WP_100881822.1	type 1 glutamine amidotransferase domain-containing protein	-
CWI26_RS11565 (CWI26_11565)	-	2333615..2334052 (+)	438	WP_100881823.1	MarR family winged helix-turn-helix transcriptional regulator	-
CWI26_RS11570 (CWI26_11570)	-	2334299..2334694 (-)	396	WP_100881824.1	hypothetical protein	-
CWI26_RS11575 (CWI26_11575)	hexA	2334840..2337380 (-)	2541	WP_100881825.1	DNA mismatch repair protein MutS	Machinery gene
CWI26_RS11580 (CWI26_11580)	argR	2337395..2337835 (-)	441	WP_100881876.1	arginine repressor	-
CWI26_RS11585 (CWI26_11585)	argS	2337942..2339630 (+)	1689	WP_100881826.1	arginine--tRNA ligase	-
CWI26_RS12065	-	2339956..2341389 (+)	1434	WP_158293419.1	SH3 domain-containing protein	-
CWI26_RS11595 (CWI26_11595)	-	2341439..2341960 (-)	522	WP_100881827.1	MFS transporter	-
CWI26_RS11600 (CWI26_11600)	-	2342088..2342282 (+)	195	WP_100881828.1	hypothetical protein	-

Sequence

Protein

• Length: 846 a.a.
• Molecular weight: 95006.48 Da
• Isoelectric Point: 4.8516

>NTDB_id=216660 CWI26_RS11575 WP_100881825.1 2334840..2337380(-) (hexA) [Streptococcus suis strain AH681]
MATEKISPGMQQYLDIKAQYPDAFLLFRMGDFYELFYEDAVEAAQILELSLTSRNKNAENPIPMAGVPYHAAQQYIDTLV
ELGHKVAIAEQMEDPKQAVGVVKREVVQVITPGTVTDSSKMGADSNYLVAIDRQGVQFALSYMDVSTGQFFVTSLDDFTS
LCGEIRNLRAREVVIGYALSEEEEQVFSNQMNLLLSFEDEVTEDVQLIDNSLTDLEKAAAGKLLSYLHRTQMRDLSHLQK
VVHYEIKDYLQMDYATKSSLDLLENGRTGKKHGSLYWLLDETKTAMGMRLLRTWIDRPLIDLKRIENRQAVVQVFLDYFF
ERSDLVEALKGVYDIERLASRVSFGKTMPKDLLQLSQTLGNIPAIKNILQQINEPALGNLVAGLDPIPELHALISSAIDP
EAQGTITDGNIIRTGFDETLDQYRLVMREGAGWIAEIEAKEREASGINNLKIDYNKKDGYYFHVTNSNLGNVPDHFFRKA
TLKNSERYGTEELAKIEGQMLEARDRSANLEYEIFMRIRQEVEKYIGRLQKLARTIATIDVLQAFAVVAEQQHLVCPRFT
DQRELTIDRGRHAVVEKVMGKQTYIPNSIHLSTDTHMQLITGPNMSGKSTYMRQLAVIVIMAQMGSYVPADQAELPIFDA
IFTRIGAADDLVSGQSTFMVEMMEANKAVRLATDRSLILFDELGRGTATYDGMALAQSIIEYIHDKIGAKTLFATHYHEL
TDLSQTLEHLENVHVSTLEKDGQVTFLHKIAQGPADKSYGIHVAKIAGMPEELLQRADRILQTLENQAPTAPAKPAPSVV
AEPSGQIDLFADTPSHPVLDELEKLDIYNMTPMEVMMAVAELKKKL

Nucleotide

• Length: 2541 bp

>NTDB_id=216660 CWI26_RS11575 WP_100881825.1 2334840..2337380(-) (hexA) [Streptococcus suis strain AH681]
ATGGCAACAGAAAAAATTTCTCCAGGCATGCAGCAGTATCTGGATATAAAAGCACAGTATCCAGATGCTTTTTTGCTGTT
TCGTATGGGTGACTTTTACGAATTATTTTATGAAGATGCGGTAGAAGCGGCACAGATTTTGGAATTGTCCTTGACCAGTC
GCAACAAAAATGCGGAGAATCCGATTCCTATGGCGGGGGTACCATATCACGCGGCACAACAGTATATCGACACACTTGTT
GAATTGGGGCACAAGGTCGCAATTGCCGAGCAGATGGAAGATCCTAAGCAGGCAGTCGGCGTGGTCAAGCGGGAAGTAGT
ACAGGTCATTACTCCTGGTACGGTAACAGACTCGTCCAAAATGGGAGCAGACAGTAACTATTTGGTTGCGATTGACCGTC
AGGGAGTGCAGTTCGCACTTTCTTATATGGATGTGTCAACAGGTCAGTTTTTTGTGACTAGTTTGGATGATTTTACTAGT
CTTTGCGGTGAAATCCGCAATTTACGGGCACGTGAAGTGGTCATAGGCTATGCTTTATCTGAGGAAGAAGAGCAGGTCTT
TTCGAACCAGATGAACCTCCTGCTCTCTTTTGAAGATGAGGTGACGGAAGATGTCCAGCTGATTGACAACTCCTTGACAG
ACTTGGAAAAGGCTGCGGCGGGCAAACTCCTCAGCTACCTACATCGGACTCAGATGCGGGATTTGAGTCACTTGCAAAAG
GTGGTCCACTATGAAATTAAGGACTATCTGCAAATGGACTATGCAACCAAGTCTAGTCTGGACTTACTTGAAAATGGTCG
GACAGGCAAGAAGCATGGTAGTTTGTACTGGTTGTTGGATGAAACCAAGACAGCCATGGGTATGCGACTATTGCGGACAT
GGATTGATCGTCCATTGATTGACCTTAAGCGGATTGAGAATCGTCAGGCTGTGGTACAGGTTTTTCTGGATTACTTCTTT
GAACGGAGTGACTTGGTCGAGGCTTTAAAAGGTGTCTATGACATCGAACGTTTGGCCAGCCGGGTGTCTTTTGGAAAAAC
CATGCCCAAGGATCTCTTGCAGCTCTCCCAGACTTTGGGAAATATTCCAGCAATCAAGAATATCTTGCAACAAATCAATG
AGCCTGCTCTAGGCAATCTGGTAGCTGGATTGGACCCAATCCCAGAACTGCATGCTCTGATCAGCTCTGCTATTGACCCA
GAAGCCCAAGGGACTATCACAGATGGAAATATCATCCGTACGGGCTTTGACGAAACGCTGGATCAGTATCGTCTGGTCAT
GCGTGAGGGAGCGGGTTGGATTGCGGAGATTGAGGCTAAGGAGCGTGAAGCGTCTGGTATCAACAATCTTAAGATTGATT
ACAACAAAAAAGACGGTTACTATTTCCATGTGACCAATTCCAATCTGGGCAATGTGCCGGACCATTTTTTCCGTAAGGCG
ACCTTGAAAAACTCGGAACGTTATGGAACGGAAGAGTTGGCTAAGATCGAAGGGCAGATGTTGGAGGCGCGTGATAGGTC
TGCTAATTTGGAGTACGAGATTTTCATGCGGATTCGCCAAGAGGTTGAGAAGTATATCGGTCGCTTGCAGAAGTTGGCTC
GAACTATTGCAACCATCGATGTTTTGCAGGCCTTTGCAGTTGTGGCGGAGCAGCAACATTTGGTTTGTCCACGCTTCACA
GATCAAAGAGAACTGACCATTGACCGTGGTCGTCATGCGGTGGTGGAGAAGGTCATGGGCAAGCAGACCTATATTCCCAA
CTCTATTCACTTGAGTACCGATACACATATGCAACTGATTACTGGTCCAAACATGAGTGGTAAGTCTACCTATATGCGGC
AGTTGGCGGTTATCGTCATCATGGCGCAGATGGGTTCCTATGTGCCTGCGGATCAGGCTGAATTGCCGATTTTCGATGCT
ATTTTCACCCGTATTGGGGCGGCAGATGACCTGGTTAGTGGTCAATCGACCTTCATGGTCGAGATGATGGAGGCCAATAA
GGCAGTCCGTCTGGCGACAGATCGTTCGCTCATCCTCTTTGATGAGTTGGGACGGGGAACAGCCACCTATGACGGTATGG
CTCTGGCCCAGTCTATCATCGAGTACATCCACGACAAGATTGGTGCCAAGACTCTTTTTGCCACCCACTACCATGAGTTG
ACAGACCTTAGCCAGACCTTGGAACACCTAGAGAATGTCCATGTATCGACCTTGGAGAAGGACGGCCAAGTCACCTTCCT
CCACAAGATTGCACAAGGCCCAGCTGACAAGTCCTACGGGATTCATGTGGCTAAGATTGCGGGAATGCCAGAGGAACTAC
TGCAGCGGGCGGATAGGATTTTGCAGACGCTTGAAAACCAAGCTCCTACTGCACCAGCAAAACCAGCTCCATCAGTGGTG
GCAGAACCGTCTGGTCAAATCGACCTCTTTGCAGACACCCCTTCTCACCCAGTCCTTGATGAACTGGAAAAACTAGACAT
CTACAATATGACCCCCATGGAAGTAATGATGGCAGTGGCGGAGTTGAAGAAAAAATTATAA

Domains

Predicted by InterProScan.

• MutS domain II (MutS_II) (126-239)

• MutS family domain IV (MutS_IV) (415-506)

• MutS domain I (MutS_I) (8-118)

• MutS domain V (MutS_V) (599-785)

• MutS domain III (MutS_III) (256-546)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	74.113	100	0.741
mutS	Pseudomonas stutzeri strain ATCC 17587	37.631	100	0.383