Detailed information NTG0021656

Bioinformatically predicted

Overview

• Name: irvR
• Type: Regulator
• Locus tag: SA_RS10370
• Genome accession: NC_002745
• Coordinates: 2044690..2045403 (+)
• Length: 237 a.a.
• NCBI ID: WP_001031454.1
• Uniprot ID: A0A0H2XG68
• Organism: Staphylococcus aureus subsp. aureus N315
• Function: regulate expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2039690..2050403

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SA_RS14830	-	2040891..2041154 (-)	264	WP_001205732.1	hypothetical protein	-
SA_RS10315 (SA1797)	-	2041163..2041423 (-)	261	WP_000291510.1	DUF1108 family protein	-
SA_RS10320 (SA1798)	-	2041428..2041730 (-)	303	WP_000165371.1	DUF2482 family protein	-
SA_RS10325 (SAS063)	-	2041825..2041986 (-)	162	WP_000048129.1	DUF1270 family protein	-
SA_RS10330 (SA1799)	-	2041983..2042306 (-)	324	WP_001120201.1	DUF771 domain-containing protein	-
SA_RS10335 (SA1800)	-	2042361..2042741 (+)	381	WP_000762521.1	DUF2513 domain-containing protein	-
SA_RS10340 (SAS064)	-	2042728..2042925 (-)	198	WP_001148856.1	hypothetical protein	-
SA_RS10345 (SA1801)	-	2042941..2043693 (-)	753	WP_001148605.1	phage antirepressor KilAC domain-containing protein	-
SA_RS10350 (SA1802)	-	2043744..2044073 (+)	330	WP_000128909.1	hypothetical protein	-
SA_RS10355 (SA1803)	-	2044062..2044277 (-)	216	WP_001025404.1	Thoeris anti-defense Tad2 family protein	-
SA_RS10360 (SA1804)	-	2044293..2044556 (-)	264	WP_000854072.1	helix-turn-helix transcriptional regulator	-
SA_RS10365	-	2044553..2044727 (-)	175	Protein_1942	transcriptional regulator	-
SA_RS10370 (SA1805)	irvR	2044690..2045403 (+)	714	WP_001031454.1	XRE family transcriptional regulator	Regulator
SA_RS10375 (SA1806)	-	2045419..2046351 (+)	933	WP_000759682.1	exonuclease domain-containing protein	-
SA_RS10380	-	2046357..2046698 (+)	342	WP_000591749.1	hypothetical protein	-
SA_RS10385 (SA1807)	-	2046902..2047084 (+)	183	WP_000694772.1	hypothetical protein	-
SA_RS10390 (SA1808)	-	2047184..2048167 (+)	984	WP_001558608.1	glycosyltransferase family 2 protein	-
SA_RS10395 (SA1809)	-	2048178..2048420 (+)	243	WP_000427213.1	hypothetical protein	-
SA_RS10400 (SA1810)	-	2048483..2049520 (+)	1038	WP_000857180.1	tyrosine-type recombinase/integrase	-
SA_RS10405 (SA1811)	sph	2049577..2050401 (+)	825	Protein_1950	sphingomyelin phosphodiesterase	-

Sequence

Protein

• Length: 237 a.a.
• Molecular weight: 27017.58 Da
• Isoelectric Point: 5.0545

>NTDB_id=21656 SA_RS10370 WP_001031454.1 2044690..2045403(+) (irvR) [Staphylococcus aureus subsp. aureus N315]
MNKERNIIIAKNIRKFLNDSNMSQKKLAELINIKPSTLSDYLNLRSNPSHGVIQRIADVFEVGKSDIDTTYKDDNDITSI
YNKLTPPRQENVLNYANEQLEEQNSKGDNVVDINSYKQEKTPVNVNGCVSAGVGERLHDETLFTEMVKGPIPTHDLALKV
NGDSMEPMFKDGEIIFVEKTHNIKNGQIGIFIIEEEAYVKKVFVEDDRLTLVSLNKDYDDLHFYRNESVRLIGKVIL

Nucleotide

• Length: 714 bp

>NTDB_id=21656 SA_RS10370 WP_001031454.1 2044690..2045403(+) (irvR) [Staphylococcus aureus subsp. aureus N315]
ATGAACAAAGAAAGAAATATTATTATAGCCAAAAACATTAGAAAATTTCTCAACGATTCAAATATGTCTCAAAAGAAACT
TGCTGAACTCATTAACATAAAACCATCTACTTTAAGCGATTATTTAAATTTACGTTCCAACCCCTCTCACGGCGTTATAC
AAAGGATAGCTGATGTTTTCGAGGTTGGTAAAAGCGACATAGATACTACATACAAAGACGATAACGACATCACTTCCATA
TACAACAAACTCACACCTCCCCGCCAAGAAAACGTACTTAACTATGCAAATGAACAATTGGAAGAACAGAATTCTAAAGG
AGATAACGTTGTAGATATTAATTCATATAAACAGGAGAAAACTCCAGTTAACGTCAATGGTTGCGTCTCTGCTGGTGTAG
GAGAACGTTTACACGATGAAACGCTATTTACTGAAATGGTTAAAGGACCTATCCCCACACACGATTTAGCGTTAAAAGTA
AATGGTGATTCTATGGAACCTATGTTTAAAGATGGCGAAATCATATTTGTGGAGAAAACTCACAATATAAAGAATGGACA
AATTGGTATATTCATCATTGAAGAAGAAGCGTATGTTAAGAAAGTCTTTGTTGAAGATGATAGATTGACTCTAGTTTCAC
TAAATAAAGATTACGACGATCTACACTTTTATAGAAATGAAAGTGTGAGGTTAATTGGAAAAGTTATTTTATAA

Domains

Predicted by InterProScan.

• Peptidase S24-like (Peptidase_S24) (127-236)

• Helix-turn-helix (HTH_3) (13-63)

3D structure

• AlphaFold DB: A0A0H2XG68

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
irvR	Streptococcus mutans UA159	33.929	100	0.401