Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   BZP34_RS14595 Genome accession   NZ_CP019563
Coordinates   2795715..2796431 (-) Length   238 a.a.
NCBI ID   WP_000688498.1    Uniprot ID   Q2VG52
Organism   Staphylococcus aureus strain SR434     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2790715..2801431
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BZP34_RS14575 (BZP34_14575) - 2791807..2792757 (+) 951 WP_000790325.1 LacI family DNA-binding transcriptional regulator -
  BZP34_RS14580 (BZP34_14580) - 2792906..2794390 (+) 1485 WP_000141414.1 sucrose-6-phosphate hydrolase -
  BZP34_RS14585 (BZP34_14585) - 2794387..2795346 (+) 960 WP_001253293.1 carbohydrate kinase family protein -
  BZP34_RS14590 (BZP34_14590) - 2795534..2795643 (-) 110 Protein_2723 hypothetical protein -
  BZP34_RS14595 (BZP34_14595) agrA 2795715..2796431 (-) 717 WP_000688498.1 quorum-sensing response regulator AgrA Regulator
  BZP34_RS14600 (BZP34_14600) agrC 2796450..2797742 (-) 1293 WP_000387809.1 quorum-sensing sensor histidine kinase AgrC -
  BZP34_RS14605 (BZP34_14605) agrD 2797767..2797907 (-) 141 WP_000735197.1 cyclic lactone autoinducer peptide AgrD -
  BZP34_RS14610 (BZP34_14610) - 2797911..2798474 (-) 564 WP_001105704.1 accessory gene regulator AgrB -
  BZP34_RS15505 hld 2798764..2798844 (+) 81 WP_000046022.1 delta-hemolysin -
  BZP34_RS14620 (BZP34_14620) - 2799444..2800229 (-) 786 WP_000867951.1 carbon-nitrogen family hydrolase -
  BZP34_RS14630 (BZP34_14630) - 2800590..2801216 (-) 627 WP_000522384.1 nitroreductase family protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27933.91 Da        Isoelectric Point: 6.0927

>NTDB_id=216400 BZP34_RS14595 WP_000688498.1 2795715..2796431(-) (agrA) [Staphylococcus aureus strain SR434]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSRDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=216400 BZP34_RS14595 WP_000688498.1 2795715..2796431(-) (agrA) [Staphylococcus aureus strain SR434]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGTTTACAATTAT
TATCAAGAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-237)

Response regulator receiver domain (Response_reg)

(3-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q2VG52

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

99.58

100

0.996

Multiple sequence alignment