Detailed information    

insolico Bioinformatically predicted

Overview

Name   ccrB   Type   Machinery gene
Locus tag   BZP34_RS10590 Genome accession   NZ_CP019563
Coordinates   2028750..2030378 (+) Length   542 a.a.
NCBI ID   WP_001186608.1    Uniprot ID   -
Organism   Staphylococcus aureus strain SR434     
Function   promote SCCmec transfer (predicted from homology)   
Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 2021254..2045689 2028750..2030378 within 0
SCCmec 2022208..2037143 2028750..2030378 within 0


Gene organization within MGE regions


Location: 2021254..2045689
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BZP34_RS10560 (BZP34_10560) - 2021378..2022178 (-) 801 WP_000749913.1 abortive infection family protein -
  BZP34_RS10565 (BZP34_10565) - 2022208..2023362 (-) 1155 WP_000912116.1 ATP-binding protein -
  BZP34_RS10570 (BZP34_10570) - 2023817..2024863 (+) 1047 WP_001042023.1 hypothetical protein -
  BZP34_RS10575 (BZP34_10575) ssb 2025056..2025352 (+) 297 WP_000273823.1 cassette chromosome ssDNA-binding protein -
  BZP34_RS10580 (BZP34_10580) cch1 2025352..2027145 (+) 1794 WP_000079473.1 cassette chromosome replicative helicase -
  BZP34_RS10585 (BZP34_10585) ccrA 2027379..2028728 (+) 1350 WP_000815640.1 cassette chromosome recombinase CcrA Machinery gene
  BZP34_RS10590 (BZP34_10590) ccrB 2028750..2030378 (+) 1629 WP_001186608.1 cassette chromosome recombinase CcrB Machinery gene
  BZP34_RS10595 (BZP34_10595) - 2030900..2031250 (+) 351 WP_000849672.1 SAUGI family uracil-DNA glycosylase inhibitor -
  BZP34_RS10600 (BZP34_10600) - 2031337..2031648 (+) 312 WP_000700851.1 DUF960 family protein -
  BZP34_RS10605 (BZP34_10605) - 2031663..2032169 (+) 507 WP_001092189.1 DUF1643 domain-containing protein -
  BZP34_RS10610 (BZP34_10610) - 2032218..2033828 (+) 1611 Protein_1987 IS1182 family transposase -
  BZP34_RS10615 (BZP34_10615) - 2033819..2034061 (-) 243 Protein_1988 type I restriction enzyme endonuclease domain-containing protein -
  BZP34_RS10620 (BZP34_10620) - 2034051..2035037 (-) 987 WP_001549960.1 beta-lactam sensor/signal transducer MecR1 -
  BZP34_RS10625 (BZP34_10625) mecA 2035134..2037143 (+) 2010 WP_001801873.1 PBP2a family beta-lactam-resistant peptidoglycan transpeptidase MecA -
  BZP34_RS10630 (BZP34_10630) - 2037189..2037617 (-) 429 WP_077156111.1 MaoC family dehydratase -
  BZP34_RS10635 (BZP34_10635) - 2037714..2038457 (-) 744 WP_000958858.1 glycerophosphoryl diester phosphodiesterase -
  BZP34_RS10640 (BZP34_10640) - 2038722..2039396 (+) 675 WP_001106057.1 IS6-like element IS257 family transposase -
  BZP34_RS10645 (BZP34_10645) aadD1 2039598..2040359 (+) 762 WP_001014230.1 aminoglycoside O-nucleotidyltransferase ANT(4')-Ia -
  BZP34_RS10650 (BZP34_10650) bleO 2040576..2040980 (+) 405 WP_001242578.1 bleomycin binding protein -
  BZP34_RS10655 (BZP34_10655) mobV 2041487..2042749 (+) 1263 WP_000119405.1 MobV family relaxase -
  BZP34_RS10660 (BZP34_10660) - 2042994..2043977 (+) 984 Protein_1997 protein rep -
  BZP34_RS10670 (BZP34_10670) - 2044068..2044742 (+) 675 WP_001106057.1 IS6-like element IS257 family transposase -
  BZP34_RS10675 (BZP34_10675) - 2044774..2045013 (-) 240 WP_001282728.1 hypothetical protein -

Sequence

Protein


Download         Length: 542 a.a.        Molecular weight: 62654.83 Da        Isoelectric Point: 9.7970

>NTDB_id=216392 BZP34_RS10590 WP_001186608.1 2028750..2030378(+) (ccrB) [Staphylococcus aureus strain SR434]
MQQLKTKRVGIYVRVSTEMQSTEGYSIDGQINQIKEYCDFHHFEVKDIYADRGISGKSMNRPELQRMLKDAKEGNIDCVM
VYKTNRLARNTSDLLKIVEDLHKQNVEFFSLSERMEVNTSSGKLMLQILASFSEFERNNIVENVFMGQTRRAQEGYYQGN
LPLGYDKIPDSKHELMINQHEANIVKYIFECYAKGHGYRKIANALNHKGYVTKKGKPFSISSITYILANPFYIGKIQFAK
YKDWSEKRRKGLNDKPVIAEGKHSPIINQDLWDKVQMRKKQVSQKPQVHGKGTNLLTGIIHCPQCGAPMAASNTTNTLKD
GTKKRIRYYSCSNFRNKGSKVCSANSVRADVIEDYVMKQILEIVKSDKVIQRVVTHVNQENQVDGAALHHDIAYKQQQYD
EVQIKINNLIKTIEDNPDLTSVIRPSIQKYEKQLNDITNQINQLKNQQNEDKTLFDAKEISKLLQHIFHDIKHIEKSRLK
ALYLSVIDRIDIKKDGNHKKQFYVTLKLNNEIIKQLFNNKQLDEVHLSTSSLFLPQTLYLTI

Nucleotide


Download         Length: 1629 bp        

>NTDB_id=216392 BZP34_RS10590 WP_001186608.1 2028750..2030378(+) (ccrB) [Staphylococcus aureus strain SR434]
ATGCAACAACTTAAAACAAAACGTGTCGGTATCTATGTACGTGTATCAACAGAAATGCAAAGCACAGAAGGTTATAGTAT
CGACGGACAAATCAATCAAATCAAAGAATACTGTGACTTCCATCATTTTGAAGTTAAAGATATATACGCTGACCGTGGTA
TTTCAGGTAAATCTATGAACAGACCTGAGCTCCAACGTATGTTGAAAGATGCAAAAGAAGGCAATATCGACTGTGTTATG
GTATACAAAACAAACCGATTAGCTCGTAATACATCTGATCTTCTCAAAATTGTCGAAGATTTACACAAACAAAATGTCGA
ATTTTTCAGTTTGTCAGAGCGTATGGAAGTCAATACTTCTTCTGGTAAACTCATGTTACAGATACTTGCGAGTTTCTCAG
AATTCGAACGTAATAACATTGTCGAGAACGTATTTATGGGTCAAACGAGACGTGCCCAAGAAGGCTATTATCAAGGCAAT
TTACCACTAGGTTATGACAAAATACCAGATAGTAAACACGAGCTAATGATTAACCAACATGAAGCTAATATTGTAAAATA
TATATTCGAGTGCTATGCCAAAGGACATGGCTATCGTAAAATTGCCAATGCATTGAATCACAAAGGATATGTCACTAAAA
AGGGGAAACCTTTCAGTATTAGTTCAATCACATACATCTTAGCTAACCCTTTCTATATCGGCAAAATTCAATTTGCGAAA
TACAAAGATTGGAGTGAAAAACGTCGTAAAGGGCTGAATGATAAACCAGTGATAGCTGAAGGTAAGCATTCCCCCATTAT
TAATCAAGATTTATGGGATAAAGTACAAATGCGTAAGAAACAAGTCAGTCAAAAACCCCAAGTCCATGGCAAAGGAACGA
ATCTGCTTACAGGCATTATTCACTGTCCCCAATGTGGCGCACCTATGGCAGCAAGCAATACCACGAATACTCTTAAAGAC
GGGACTAAGAAACGTATTCGTTACTATTCATGTAGTAATTTTCGGAACAAGGGTTCCAAAGTATGTTCGGCAAACAGTGT
AAGAGCTGATGTGATTGAAGATTATGTGATGAAGCAAATACTTGAAATAGTCAAAAGTGATAAAGTCATTCAACGCGTAG
TAACACACGTCAATCAAGAAAATCAAGTTGATGGCGCTGCACTTCATCACGATATTGCTTATAAGCAACAACAATATGAT
GAAGTACAAATCAAAATAAATAACTTGATTAAAACCATCGAGGATAATCCGGACTTAACATCAGTAATCAGACCAAGTAT
TCAAAAATATGAAAAGCAACTCAATGACATTACGAATCAAATCAACCAACTCAAAAATCAACAAAATGAAGATAAGACTT
TATTTGATGCCAAAGAAATCAGTAAACTATTACAACACATCTTTCATGATATTAAGCACATAGAAAAATCTCGACTCAAA
GCATTGTATCTATCAGTGATTGATCGCATTGATATTAAAAAAGATGGTAATCATAAAAAACAATTCTATGTCACACTCAA
ACTTAATAACGAAATCATTAAACAACTTTTCAATAATAAACAACTCGACGAAGTGCATCTCAGCACTTCGTCTTTATTTT
TGCCCCAAACACTATATCTTACTATTTAG

Domains

Predicted by InterproScan.

Recombinase (Recombinase)

(180-280)

Resolvase, N terminal domain (Resolvase)

(11-156)

Ogr/Delta-like zinc finger (Ogr_Delta)

(301-356)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ccrB Staphylococcus aureus N315

98.893

100

0.989

Multiple sequence alignment