Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   NMA_RS03075 Genome accession   NC_003116
Coordinates   583916..587029 (-) Length   1037 a.a.
NCBI ID   WP_010981100.1    Uniprot ID   A0A0U1RHL7
Organism   Neisseria meningitidis Z2491     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 578916..592029
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NMA_RS15025 - 579098..579449 (+) 352 Protein_580 hypothetical protein -
  NMA_RS03050 (NMA0605) - 579695..580084 (-) 390 WP_002219820.1 endonuclease domain-containing protein -
  NMA_RS03060 (NMA0607) - 580363..580500 (-) 138 WP_002214606.1 VOC family protein -
  NMA_RS03065 (NMA0608) carA 580546..581679 (-) 1134 WP_002223013.1 glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit -
  NMA_RS03075 (NMA0609) pilC 583916..587029 (-) 3114 WP_010981100.1 PilC family type IV pilus tip adhesin Machinery gene
  NMA_RS03085 (NMA0611) apbC 587959..589038 (-) 1080 WP_002247061.1 iron-sulfur cluster carrier protein ApbC -
  NMA_RS03095 (NMA0612) - 589403..589912 (+) 510 WP_002225670.1 protein disulfide oxidoreductase -
  NMA_RS03105 (NMA0613) nadR 590256..590696 (+) 441 WP_002214596.1 MarR family adhesin repressor NadR -
  NMA_RS03110 (NMA0614) hpaC 590811..591311 (+) 501 WP_002224077.1 4-hydroxyphenylacetate 3-monooxygenase, reductase component -
  NMA_RS03115 (NMA0615) murU 591329..592024 (+) 696 WP_002247054.1 N-acetylmuramate alpha-1-phosphate uridylyltransferase MurU -

Sequence

Protein


Download         Length: 1037 a.a.        Molecular weight: 113752.39 Da        Isoelectric Point: 9.7564

>NTDB_id=21633 NMA_RS03075 WP_010981100.1 583916..587029(-) (pilC) [Neisseria meningitidis Z2491]
MNKTLKRRVFRHTALYAAILMFSHTGGGGGAMAQTRQYAIIMNERNQPEVQWNGSYSIKDKDRKREYTHHNHQQGGSSVS
FNNSDELVSRQSGTAVFGTATYLPPYGKVSGFDAAALKERNNAVDWIHTTHPGLIGYSYDGVVCRSATDCPKLVYKTRFS
FDNPDLAKTGGGLDKHTEPSRDNSPIYKLKDHPWLGVSFNLGAEGIAKNGKTINKLVSSFNEKNSNNNLVYTTEGRDISL
GNWQRETTAMAYYLNAKLHLLDKKQIQNITDKTVQLGVLKPSIDVRTRNTGTAGILSYWAKWDIKDTGQIPVKLSLTQVK
AGRCVNKDNPNKNTKTSSPALTAPALWFGAGQDGKAEMYSASVSTYPDSSSSRIFLQNLKRKTDTSRPGRYSLATLNKSD
IESREPSFTSRQTVIRLDGGVQQIKLDRNNTEVTGFNGNDGKNDTFGIVSEGSFMPDASEWKKVLLPWTVRAFNYDGRFN
TVNKEENNGKPKYSQKYRSRNNGKHERNLGDIVNSPIVAVGEYLATSANDGMVHIFKQSGGDKRSYNLKLSYIPGTMPRK
DIESKDSTLAKELRAFAEKGYVGDRYGVDGGFVLRRITDDQDKQKHFFMFGAMGLGGRGAYALDLTKADDNDPTKASLFD
VKDNGNNGNNGNNRVELGYTVGTPQIGKTHNGKYAAFLASGYATKQIDSGENKTALYVYDLESNNGTLIRKIEVTDGKGG
LSSPTLVDKDLDGTVDIAYAGDRGGKMYRFDLSGNNPNSWTVRTIFQGTKPITSAPAISQLKDKRVVIFGTGSDLSEDDV
LSTDEQHIYGIFDNDTNTGTAQEGLGKGLLEQKLSEENKTLFLTDYKRSDGSGDKGWVVKLKDGQRVTVKPTVVLRTAFV
TIHKYTGNDKCGAETAILGINTADGGKLTKKSARPIVPAANSKVAQYSGDKKTSSGKSIPIGCMEKDGGTVCPNGYVYDK
PVNVRYLDEKKTDGFSTTADGDAGGSGTFKEGKKPARNNRCFSGKGVRTLLMNDLDSLDITGPMCGMKRISWREVFY

Nucleotide


Download         Length: 3114 bp        

>NTDB_id=21633 NMA_RS03075 WP_010981100.1 583916..587029(-) (pilC) [Neisseria meningitidis Z2491]
ATGAATAAAACTTTAAAAAGGCGGGTTTTCCGCCATACCGCGCTTTATGCCGCCATCTTGATGTTTTCCCATACCGGCGG
GGGGGGGGGGGCGATGGCGCAAACCCGTCAATACGCTATTATCATGAACGAGAGAAACCAGCCCGAGGTACAGTGGAATG
GGTCATATTCAATAAAGGACAAAGACAGGAAGCGCGAATATACTCATCATAATCACCAACAAGGAGGAAGCTCTGTCTCA
TTCAACAATAGCGATGAGCTTGTTTCTCGACAAAGCGGTACTGCCGTTTTTGGCACAGCCACCTACCTGCCGCCCTACGG
CAAGGTTTCCGGTTTTGATGCCGCCGCTCTGAAAGAGCGCAACAATGCCGTCGATTGGATTCATACCACCCACCCAGGGT
TGATAGGCTACAGCTACGACGGTGTCGTATGCAGAAGCGCCACAGACTGTCCCAAACTTGTCTATAAAACCCGATTTTCC
TTCGATAATCCCGACTTGGCAAAAACAGGAGGCGGGTTGGATAAGCACACAGAGCCAAGCCGCGACAATTCGCCCATTTA
CAAATTGAAGGATCATCCATGGTTGGGCGTGTCTTTCAATTTGGGTGCCGAGGGTATCGCCAAAAATGGTAAGACAATCA
ACAAATTGGTATCTTCTTTTAATGAAAAGAATAGTAATAACAACCTCGTCTATACCACGGAAGGCCGCGATATTTCCTTG
GGCAACTGGCAGCGCGAAACGACCGCCATGGCCTATTATCTGAACGCCAAGCTGCACCTGCTGGATAAAAAACAGATTCA
AAATATCACCGACAAAACAGTGCAGTTGGGTGTCTTGAAGCCGAGCATCGATGTGCGGACAAGAAATACGGGGACTGCCG
GCATTCTATCTTATTGGGCTAAGTGGGACATTAAAGATACCGGGCAGATTCCAGTCAAGCTCAGCTTGACGCAAGTCAAA
GCAGGCCGCTGCGTCAACAAAGATAACCCCAATAAGAATACCAAAACCTCTTCCCCCGCACTGACTGCCCCCGCGCTGTG
GTTCGGAGCTGGGCAAGATGGTAAGGCGGAGATGTATTCCGCTTCGGTTTCCACCTACCCCGACAGTTCGAGCAGCCGCA
TCTTCCTTCAAAATCTGAAAAGAAAAACCGACACCAGCAGACCCGGCCGCTATTCCCTCGCAACCTTGAATAAGTCGGAT
ATTGAAAGTCGAGAGCCGAGTTTCACAAGTCGGCAAACCGTCATCCGATTGGATGGCGGCGTACAGCAGATCAAACTGGA
TAGAAACAATACTGAGGTCACTGGTTTTAATGGAAATGACGGCAAAAACGACACTTTCGGCATTGTTAGTGAAGGGAGCT
TCATGCCTGATGCCAGCGAGTGGAAAAAAGTATTGCTGCCTTGGACGGTTCGTGCTTTCAATTATGACGGTCGATTTAAC
ACAGTCAACAAAGAAGAAAACAACGGCAAGCCAAAATACAGTCAAAAATACCGCAGCCGCAACAACGGCAAGCACGAGCG
CAATTTGGGCGACATCGTCAACAGCCCCATCGTGGCGGTCGGCGAGTATTTGGCTACTTCCGCCAACGACGGGATGGTGC
ATATCTTCAAACAAAGCGGCGGGGACAAGCGCAGCTACAATCTGAAGCTCAGCTACATCCCCGGCACGATGCCGCGCAAG
GATATTGAAAGCAAAGACTCCACCCTTGCCAAAGAGCTGCGCGCCTTTGCCGAAAAAGGCTATGTGGGCGACCGCTACGG
CGTGGACGGCGGCTTTGTCTTGCGCCGCATTACAGATGACCAAGACAAGCAAAAACACTTCTTTATGTTCGGCGCAATGG
GCCTTGGCGGCAGAGGCGCATACGCCTTGGATTTGACCAAAGCCGACGACAATGACCCGACAAAAGCCTCTTTGTTTGAT
GTAAAAGATAACGGCAATAATGGCAATAACGGCAATAATCGCGTGGAATTAGGCTACACCGTCGGCACGCCGCAAATCGG
CAAAACCCACAACGGCAAATACGCCGCCTTCCTCGCCTCCGGTTATGCGACTAAACAGATTGACAGCGGCGAGAATAAAA
CCGCGCTGTATGTGTATGATTTGGAAAGCAACAACGGTACGCTGATTAGAAAAATCGAAGTAACCGACGGCAAGGGCGGG
CTTTCGTCCCCCACGCTGGTGGATAAAGATTTGGACGGCACGGTCGATATCGCCTATGCCGGCGATCGCGGCGGCAAGAT
GTACCGCTTTGATTTAAGCGGCAACAACCCGAACAGTTGGACTGTACGCACTATTTTCCAAGGCACGAAGCCGATTACTT
CCGCGCCCGCCATTTCCCAACTGAAAGACAAACGCGTGGTTATCTTCGGTACGGGCAGTGATTTGAGTGAGGATGATGTA
CTCAGTACGGATGAACAACATATTTACGGTATTTTTGACAATGACACAAACACGGGTACGGCGCAAGAGGGGCTGGGCAA
AGGGCTGCTCGAGCAAAAGCTTAGTGAGGAAAATAAAACCTTATTCCTGACCGATTATAAGCGATCCGACGGCTCGGGCG
ACAAGGGCTGGGTAGTGAAATTGAAGGACGGACAGCGCGTTACCGTCAAACCGACCGTGGTATTGCGTACCGCCTTTGTA
ACCATCCATAAATATACGGGTAATGACAAATGCGGCGCGGAAACCGCCATTTTGGGCATCAATACCGCCGACGGCGGCAA
GCTGACCAAGAAAAGCGCGCGCCCGATTGTGCCGGCAGCCAATTCGAAGGTCGCGCAATATTCCGGCGATAAGAAAACTT
CCAGCGGCAAATCCATCCCTATAGGTTGTATGGAAAAAGACGGGGGAACCGTCTGCCCGAACGGATATGTTTACGACAAA
CCGGTTAATGTGCGCTACCTGGACGAAAAGAAAACAGACGGATTTTCAACAACGGCAGACGGCGATGCGGGCGGCAGCGG
AACATTCAAAGAGGGTAAAAAACCCGCCCGCAATAACCGGTGCTTCTCCGGAAAAGGGGTGCGCACCCTGCTGATGAACG
ATTTGGACAGCTTGGATATTACCGGCCCGATGTGCGGTATGAAACGAATCAGCTGGCGTGAAGTCTTCTACTGA

Domains

Predicted by InterproScan.

Neisseria PilC beta-propeller domain (T4P_PilY1)

(509-844)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0U1RHL7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Neisseria meningitidis A1493

76.291

100

0.77

Multiple sequence alignment