Detailed information NTG0216211

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: BZG42_RS02345
• Genome accession: NZ_CP019557
• Coordinates: 457580..459802 (-)
• Length: 740 a.a.
• NCBI ID: WP_155969646.1
• Uniprot ID: -
• Organism: Streptococcus sp. DAT741
• Function: degradation of ComX (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IS/Tn	456974..457438	457580..459802	flank	142

Gene organization within MGE regions

Location: 456974..459802

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BZG42_RS02340 (BZG42_02325)	tnpA	456974..457438 (+)	465	WP_155996283.1	IS200/IS605 family transposase	-
BZG42_RS02345 (BZG42_02335)	clpE	457580..459802 (-)	2223	WP_155969646.1	ATP-dependent Clp protease ATP-binding subunit	Regulator

Sequence

Protein

• Length: 740 a.a.
• Molecular weight: 82378.68 Da
• Isoelectric Point: 5.3516

>NTDB_id=216211 BZG42_RS02345 WP_155969646.1 457580..459802(-) (clpE) [Streptococcus sp. DAT741]
MLCKNCNINDATIHLYTNLNGKQQQVDLCHNCYQIMKTDPNNAILRGLGDMVNPNNMDPFSEFFNHLGGYPGNTPAGKKR
EQTPPTQSGGSHNGRGGQTPPPQQPNGLLEEFGINVTDIARRGDIDPVIGRDQEITRVIEILNRRTKNNPVLIGEPGVGK
TAVVEGLAQKIVDGDVPQKLRGKEVIRLDVVSLVQGTGIRGQFEERMQKLMEEIRNRREIILFIDEIHEIVGAGSAGDGN
MDAGNILKPALARGEMQLVGATTLNEYRIIEKDAALERRMQPVKVEEPSVEETITILKGIQSKYQDYHHVKYSDTAIEAA
AVLSNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFVDPREIDQRLLDAENRKAQATRDEDYEKAAYFRDQIAKYKEMQKAT
ISEEDTPLITEKEIEAIVEQKTNIPVGDLKEKEQSQLINLASDLKAHVIGQDEAVDKIAKAIRRNRVGLGAPNRPIGSFL
FVGPTGVGKTELSKQLAIELFGSADSMIRFDMSEYMEKHAIAKLVGAPPGYVGYEEAGQLTEKVRRNPYSLILLDEIEKA
HPDVLHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKVEASVGFGASIEGRTQSVLGQLSNFFTPEFMNRFDGII
EFQPLSKENLLEIVSLMLEDVNQRLSHNGINLHVTDKVKEKLVDLGYDPKMGARPLRRTIQDQIEDAITDFYLENPSEKN
LRAVMTSKGTIQIKAQTKTK

Nucleotide

• Length: 2223 bp

>NTDB_id=216211 BZG42_RS02345 WP_155969646.1 457580..459802(-) (clpE) [Streptococcus sp. DAT741]
ATGCTCTGCAAAAATTGTAATATCAACGACGCAACGATCCATCTCTATACCAATCTAAACGGTAAACAGCAACAGGTTGA
CCTCTGTCACAATTGTTATCAAATCATGAAAACAGATCCAAATAATGCTATCCTACGCGGCTTAGGTGACATGGTAAATC
CTAATAATATGGATCCATTTAGCGAGTTCTTCAATCATCTGGGAGGCTATCCAGGTAATACACCTGCTGGCAAAAAACGT
GAACAGACCCCTCCAACTCAGTCTGGCGGAAGTCACAATGGTCGTGGTGGGCAGACGCCTCCTCCACAACAGCCCAATGG
TCTCTTGGAAGAATTTGGAATCAATGTGACCGATATTGCTCGCCGAGGCGACATTGACCCAGTAATTGGTCGCGATCAAG
AAATTACACGGGTCATTGAGATTCTCAACCGCAGGACCAAAAACAATCCCGTCCTCATCGGAGAGCCAGGTGTGGGTAAG
ACTGCGGTTGTTGAAGGTCTAGCTCAAAAAATCGTTGATGGTGATGTTCCACAAAAACTGCGAGGAAAAGAGGTTATCCG
ACTCGATGTGGTAAGTTTGGTCCAAGGGACAGGCATTCGCGGGCAATTTGAAGAACGGATGCAAAAACTGATGGAAGAAA
TCCGCAACCGCCGGGAAATCATCCTCTTTATTGATGAGATCCATGAAATCGTCGGAGCTGGTTCTGCCGGTGATGGTAAT
ATGGATGCAGGAAACATTCTCAAGCCAGCTTTGGCTCGTGGGGAAATGCAATTAGTAGGGGCAACCACCCTCAACGAATA
CCGCATCATTGAGAAGGATGCTGCTCTTGAACGACGCATGCAACCAGTAAAAGTAGAAGAACCTAGCGTTGAAGAAACAA
TCACCATTCTCAAGGGTATTCAAAGCAAATACCAAGATTATCACCACGTTAAGTATTCAGATACGGCCATTGAAGCTGCA
GCTGTTCTTTCCAATCGCTATATTCAAGACCGCTTTCTACCAGACAAGGCCATTGACCTACTGGACGAAGCCGGCTCCAA
AATGAACCTGACCCTCAACTTTGTTGACCCAAGGGAAATTGATCAGCGCTTGCTTGACGCTGAGAATCGTAAGGCTCAAG
CCACACGTGACGAAGATTATGAAAAAGCAGCTTATTTCCGCGATCAGATTGCAAAGTATAAGGAAATGCAAAAGGCTACC
ATCAGCGAAGAGGATACACCGCTCATTACCGAAAAAGAAATCGAAGCCATTGTCGAGCAAAAGACCAATATCCCCGTTGG
TGATTTGAAAGAAAAAGAACAATCACAGCTCATCAATCTAGCAAGCGATCTAAAAGCGCATGTTATCGGTCAAGATGAGG
CCGTTGATAAGATTGCAAAGGCTATCCGCCGTAATCGTGTCGGTCTGGGAGCACCAAATCGCCCAATCGGCTCCTTCCTC
TTTGTTGGTCCGACTGGCGTCGGAAAAACAGAATTGTCCAAACAACTCGCCATTGAACTCTTTGGATCGGCGGACAGTAT
GATTCGCTTTGATATGTCCGAATACATGGAAAAACACGCTATTGCCAAGTTAGTCGGGGCACCCCCAGGCTATGTCGGTT
ATGAAGAAGCAGGACAACTAACAGAAAAAGTTCGCCGCAATCCTTATTCACTCATCCTCTTAGATGAGATAGAAAAGGCC
CATCCGGATGTCTTACACATGTTCCTCCAAGTCTTGGATGATGGGCGTTTGACAGACGGACAAGGGCGGACAGTCAGCTT
TAAAGACACCATCATCATCATGACGTCCAATGCGGGAACAGGTAAGGTTGAAGCCAGCGTTGGTTTTGGTGCCAGCATAG
AAGGACGGACACAATCTGTCCTCGGTCAACTCAGCAACTTCTTTACCCCAGAGTTCATGAATCGTTTTGATGGAATTATC
GAATTCCAACCGCTCAGCAAGGAAAATCTACTAGAAATCGTCAGCCTCATGTTGGAGGATGTCAACCAGCGGCTTTCTCA
CAACGGTATCAACCTACATGTCACAGATAAGGTCAAGGAAAAATTGGTTGACTTGGGCTACGACCCAAAAATGGGAGCTC
GTCCGCTTCGCCGAACTATCCAAGATCAAATTGAGGACGCTATTACTGATTTTTATCTGGAAAATCCAAGTGAAAAGAAC
CTGCGAGCAGTCATGACGAGCAAGGGAACTATCCAAATCAAGGCTCAAACAAAAACCAAATAA

Domains

Predicted by InterproScan.

• AAA lid domain (AAA_lid_9) (289-387)

• AAA domain (Cdc48 subfamily) (AAA_2) (474-637)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (645-720)

• ATPase family associated with various cellular activities (AAA) (AAA) (151-270)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus pneumoniae Rx1	82.29	100	0.835
clpE	Streptococcus pneumoniae D39	82.29	100	0.835
clpE	Streptococcus pneumoniae R6	82.29	100	0.835
clpE	Streptococcus pneumoniae TIGR4	82.29	100	0.835
clpE	Streptococcus mutans UA159	81.684	100	0.826
clpC	Lactococcus lactis subsp. cremoris KW2	77.455	97.703	0.757
clpC	Bacillus subtilis subsp. subtilis str. 168	50.744	90.811	0.461
clpC	Streptococcus thermophilus LMD-9	47.656	86.486	0.412
clpC	Streptococcus thermophilus LMG 18311	47.344	86.486	0.409
clpC	Streptococcus pneumoniae TIGR4	47.68	84.459	0.403
clpC	Streptococcus pneumoniae Rx1	47.68	84.459	0.403
clpC	Streptococcus pneumoniae D39	47.68	84.459	0.403
clpC	Streptococcus mutans UA159	47.512	84.189	0.4
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	46.08	84.459	0.389