Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   CFP59_RS25715 Genome accession   NZ_CP025018
Coordinates   6149195..6149908 (+) Length   237 a.a.
NCBI ID   WP_069860877.1    Uniprot ID   A0A2J7ZDG8
Organism   Streptomyces sp. M56     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 6144195..6154908
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CFP59_RS25700 (CFP59_05070) - 6145275..6146417 (-) 1143 WP_100806889.1 NADH-quinone oxidoreductase subunit D -
  CFP59_RS25705 (CFP59_05071) - 6146773..6147795 (-) 1023 WP_100806890.1 SAM-dependent methyltransferase -
  CFP59_RS25710 (CFP59_05072) - 6147904..6149100 (+) 1197 WP_100809307.1 sensor histidine kinase -
  CFP59_RS25715 (CFP59_05073) vraR 6149195..6149908 (+) 714 WP_069860877.1 response regulator transcription factor Regulator
  CFP59_RS25720 (CFP59_05074) - 6149939..6150310 (-) 372 WP_100806891.1 helix-turn-helix domain-containing protein -
  CFP59_RS25725 (CFP59_05075) - 6150530..6151612 (-) 1083 WP_069860875.1 DUF5937 family protein -
  CFP59_RS25735 (CFP59_05077) - 6151919..6153247 (-) 1329 WP_100806892.1 beta-eliminating lyase-related protein -
  CFP59_RS25740 (CFP59_05078) - 6153395..6154330 (+) 936 WP_069860872.1 DUF2520 domain-containing protein -

Sequence

Protein


Download         Length: 237 a.a.        Molecular weight: 24963.99 Da        Isoelectric Point: 6.4979

>NTDB_id=216095 CFP59_RS25715 WP_069860877.1 6149195..6149908(+) (vraR) [Streptomyces sp. M56]
MSIRVMLVDDQVLLRTGFRMVLAAQPDMEVVAEAGDGVEALAAVRSTAIDVILMDVRMPKLDGVEATRRICEREDAPKVI
ILTTFDLDEYAFSALKAGAAGFMLKDVPPGELLAAIRAVHSGDAVVAPSTTRRLLDRFAPMLPGGGAGGSGGRARPGLER
LTDREREVVLLVAQGLSNGEIAARLVLSEATVKTHVGRILTKLELRDRVQVVVMAYETGLVRAGGPAGPAGSAGSAR

Nucleotide


Download         Length: 714 bp        

>NTDB_id=216095 CFP59_RS25715 WP_069860877.1 6149195..6149908(+) (vraR) [Streptomyces sp. M56]
ATGTCGATCCGCGTCATGCTCGTCGATGACCAAGTGCTGCTGCGCACCGGCTTCCGGATGGTGCTCGCGGCCCAGCCCGA
TATGGAGGTCGTCGCCGAGGCGGGCGATGGGGTGGAGGCGCTGGCGGCGGTGCGCTCCACGGCGATCGACGTCATCCTCA
TGGACGTCCGGATGCCCAAACTCGACGGGGTGGAGGCGACCCGGCGGATATGTGAACGCGAGGACGCGCCGAAGGTCATC
ATCCTGACCACTTTCGACCTGGACGAATACGCCTTCTCGGCGCTGAAGGCCGGGGCGGCCGGCTTCATGCTCAAGGATGT
GCCGCCGGGTGAGCTGCTCGCGGCGATCCGCGCGGTGCACAGCGGTGACGCGGTGGTCGCGCCCAGTACGACGCGCCGGC
TGCTGGACCGGTTCGCGCCGATGCTGCCGGGCGGCGGGGCCGGTGGCTCCGGGGGCCGGGCCCGTCCGGGGCTGGAGCGG
CTCACCGACCGGGAGCGCGAGGTGGTGCTGCTGGTCGCGCAGGGGCTGTCGAACGGTGAGATCGCGGCGCGGCTGGTGCT
GTCCGAGGCCACCGTGAAGACCCATGTGGGGCGCATCCTCACCAAGCTGGAGCTGCGGGACCGGGTGCAGGTGGTGGTGA
TGGCCTACGAGACGGGGCTGGTGCGGGCCGGGGGTCCGGCGGGGCCGGCCGGGTCGGCCGGATCGGCTCGCTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(161-215)

Response regulator receiver domain (Response_reg)

(5-117)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2J7ZDG8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

38.222

94.937

0.363