Detailed information NTG0215863

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: CVO91_RS12350
• Genome accession: NZ_CP024974
• Coordinates: 2437701..2440241 (-)
• Length: 846 a.a.
• NCBI ID: WP_002941940.1
• Uniprot ID: -
• Organism: Streptococcus suis strain CZ130302
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 2432701..2445241

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CVO91_RS12320 (CVO91_12320)	-	2433095..2433472 (-)	378	WP_002941954.1	LytTR family DNA-binding domain-containing protein	-
CVO91_RS12325 (CVO91_12325)	-	2433764..2434417 (-)	654	WP_002941951.1	DUF998 domain-containing protein	-
CVO91_RS12330 (CVO91_12330)	-	2434429..2435772 (-)	1344	WP_002941948.1	NAD(P)/FAD-dependent oxidoreductase	-
CVO91_RS12335 (CVO91_12335)	-	2435785..2436465 (-)	681	WP_002941947.1	type 1 glutamine amidotransferase domain-containing protein	-
CVO91_RS12340 (CVO91_12340)	-	2436600..2437037 (+)	438	WP_002941944.1	MarR family transcriptional regulator	-
CVO91_RS12345 (CVO91_12345)	-	2437160..2437555 (-)	396	WP_002941942.1	hypothetical protein	-
CVO91_RS12350 (CVO91_12350)	hexA	2437701..2440241 (-)	2541	WP_002941940.1	DNA mismatch repair protein MutS	Machinery gene
CVO91_RS12355 (CVO91_12355)	argR	2440256..2440696 (-)	441	WP_002941938.1	arginine repressor	-
CVO91_RS12360 (CVO91_12360)	argS	2440803..2442491 (+)	1689	WP_002941936.1	arginine--tRNA ligase	-
CVO91_RS12365 (CVO91_12365)	-	2442671..2443624 (+)	954	WP_002941934.1	SH3 domain-containing protein	-
CVO91_RS12370 (CVO91_12370)	-	2443675..2444199 (-)	525	WP_002941931.1	hypothetical protein	-
CVO91_RS12375 (CVO91_12375)	-	2444327..2444521 (+)	195	WP_002941929.1	hypothetical protein	-
CVO91_RS12380 (CVO91_12380)	-	2444561..2444860 (-)	300	WP_002941928.1	hypothetical protein	-

Sequence

Protein

• Length: 846 a.a.
• Molecular weight: 95123.55 Da
• Isoelectric Point: 4.7732

>NTDB_id=215863 CVO91_RS12350 WP_002941940.1 2437701..2440241(-) (hexA) [Streptococcus suis strain CZ130302]
MATEKISPGMQQYLDIKANYPDAFLLFRMGDFYELFYEDAVEAAQILELSLTSRNKNAENPIPMAGVPYHAAQQYIDTLV
ELGHKVAIAEQMEDPKQAVGVVKREVVQVITPGTVTDSSKMGADSNYLVAIDRQGVQFALSYMDVSTGQFFVTSLDDFTS
LCGEIRNLRARELVIGYALSEEEEQVFSNQMNLLLSFEDEVTEDVQLIDNSLTDLEKAAAGKLLSYLHRTQMRDLSHLQK
VVHYEIKDYLQMDYATKSSLDLLENGRTGKKHGSLYWLLDETKTAMGMRLLRAWIDRPLIDLKRIESRQAVVQVFLDYFF
ERSDLVEALKGVYDIERLASRVSFGKTMPKDLLQLSQTLGNVPAIKNILQQMDQPALTSLVAGLDPIPELHALISSAIDP
DAQGAITDGNIIRTGFDETLDQYRLVMREGAGWIAEIEAKEREASGINNLKIDYNKKDGYYFHVTNSNLDNVPDHFFRKA
TLKNSERYGTEELAKIEGQMLEARDKSANLEYEIFMRIRQEVEKYIGRLQKLARTIATIDVLQAFAVVAEQQHLVCPRFT
DQRELTIDRGRHAVVEKVMGKQTYIPNSIHLNTDTHMQLITGPNMSGKSTYMRQLAVIVIMAQMGSYVPADQAELPIFDA
IFTRIGAADDLVSGQSTFMVEMMEANKAVRLATDRSLILFDELGRGTATYDGMALAQSIIEYIHDKIGAKTLFATHYHEL
TDLSQTLEHLENVHVSTLEKDGQVTFLHKIAQGPADKSYGIHVAKIAGMPEELLERADRILQTLENQAPTAPTHPIPSVV
EEPSGQLDLFADTPSHPVLDELEKLDIYNMTPMEVMMAVAELKKKL

Nucleotide

• Length: 2541 bp

>NTDB_id=215863 CVO91_RS12350 WP_002941940.1 2437701..2440241(-) (hexA) [Streptococcus suis strain CZ130302]
ATGGCAACAGAAAAAATTTCTCCGGGAATGCAGCAGTATCTGGATATAAAAGCAAACTATCCAGATGCTTTTTTGCTTTT
CCGTATGGGAGACTTTTATGAATTATTTTATGAAGATGCGGTAGAAGCGGCACAGATTTTGGAATTGTCCTTGACCAGTC
GGAATAAGAATGCGGAGAATCCGATTCCTATGGCGGGGGTACCGTATCACGCTGCACAACAGTATATCGACACACTTGTT
GAATTGGGGCACAAGGTCGCAATTGCCGAGCAAATGGAGGATCCCAAACAGGCAGTCGGTGTGGTCAAGCGGGAAGTAGT
ACAGGTCATTACTCCTGGTACGGTAACAGACTCGTCCAAAATGGGAGCAGACAGTAACTATTTGGTTGCGATTGACCGTC
AGGGCGTACAATTTGCCCTGTCCTACATGGATGTCTCAACAGGTCAGTTTTTCGTGACTAGTCTTGATGATTTTACCAGC
CTCTGCGGTGAAATCCGCAATTTACGGGCAAGGGAATTGGTCATCGGCTATGCTTTATCTGAGGAAGAAGAGCAGGTCTT
CTCTAACCAGATGAACCTCCTACTCTCTTTTGAGGATGAGGTGACGGAAGATGTCCAGCTGATTGACAACTCCCTGACAG
ACTTGGAAAAGGCTGCAGCAGGCAAACTCCTCAGCTACCTACATCGGACACAGATGCGGGACTTGAGTCACTTGCAAAAG
GTGGTCCATTATGAAATCAAGGACTATCTGCAAATGGACTACGCTACCAAGTCTAGTCTGGACTTGCTTGAAAATGGACG
GACAGGCAAGAAGCATGGTAGTTTGTACTGGTTGTTAGACGAAACCAAGACAGCTATGGGCATGCGGCTCTTGCGGGCTT
GGATTGACAGACCGCTGATTGACCTCAAGCGGATTGAAAGTCGGCAGGCTGTTGTGCAGGTTTTTCTGGACTACTTCTTT
GAGCGGAGTGATTTGGTAGAAGCCTTGAAAGGTGTCTATGACATCGAACGCTTGGCCAGTCGGGTGTCTTTCGGAAAAAC
TATGCCCAAGGACCTCTTGCAACTTTCTCAGACCTTGGGAAATGTCCCTGCTATCAAGAACATCTTGCAACAAATGGACC
AGCCTGCTCTGACTAGCTTGGTGGCAGGTCTGGATCCAATCCCAGAACTGCACGCTCTCATCAGCTCTGCTATTGACCCA
GATGCCCAAGGGGCTATTACAGACGGCAATATCATCCGCACGGGCTTTGATGAAACCTTGGACCAGTACCGTCTGGTCAT
GCGTGAGGGTGCGGGCTGGATTGCGGAGATTGAGGCTAAGGAGCGTGAAGCATCTGGTATCAACAATCTCAAGATTGATT
ACAACAAAAAAGACGGTTACTATTTCCATGTGACCAATTCCAATTTGGACAATGTGCCGGACCATTTTTTCCGTAAGGCG
ACCTTGAAAAACTCGGAGCGCTATGGAACGGAAGAGTTGGCTAAGATCGAAGGGCAGATGTTGGAGGCGCGTGATAAGTC
TGCTAATTTGGAGTACGAGATTTTCATGCGGATTCGCCAAGAGGTTGAGAAGTATATTGGTCGCTTGCAGAAGTTGGCTC
GGACCATTGCAACCATCGATGTTTTGCAGGCCTTTGCAGTTGTGGCGGAGCAGCAACATTTGGTTTGTCCACGCTTCACA
GATCAAAGAGAACTGACCATTGACCGTGGTCGTCATGCGGTGGTGGAGAAGGTCATGGGCAAGCAGACCTACATTCCCAA
CTCTATTCACCTGAATACCGATACGCATATGCAACTAATTACAGGTCCAAACATGAGTGGTAAGTCTACCTATATGCGGC
AGTTGGCGGTTATCGTCATCATGGCGCAGATGGGTTCCTATGTGCCTGCGGATCAGGCTGAATTACCGATTTTCGATGCT
ATTTTCACCCGAATTGGGGCGGCAGACGACTTGGTTAGTGGTCAATCGACCTTCATGGTCGAAATGATGGAGGCCAACAA
GGCCGTGCGTTTGGCGACAGATCGTTCGCTCATCCTCTTTGACGAACTTGGACGGGGAACGGCCACCTATGATGGTATGG
CCCTAGCCCAGTCTATCATCGAGTACATCCACGACAAGATTGGTGCCAAAACCCTCTTTGCCACCCACTACCATGAGTTG
ACAGACCTTAGCCAGACCTTGGAACACTTAGAGAATGTCCATGTATCGACCTTGGAGAAGGACGGTCAAGTCACCTTCCT
CCACAAGATTGCCCAAGGTCCAGCTGACAAGTCCTACGGGATTCATGTGGCTAAGATTGCGGGAATGCCAGAGGAGTTAT
TGGAGCGAGCGGATAGGATTTTGCAGACGCTTGAAAACCAAGCCCCTACTGCACCAACTCACCCAATTCCGTCAGTAGTA
GAAGAACCGTCAGGTCAACTTGATCTCTTCGCAGACACGCCTTCTCACCCAGTACTTGATGAACTGGAAAAACTAGACAT
CTACAATATGACCCCTATGGAAGTCATGATGGCAGTGGCGGAGTTGAAGAAGAAACTATAA

Domains

Predicted by InterProScan.

• MutS domain I (MutS_I) (8-118)

• MutS family domain IV (MutS_IV) (415-505)

• MutS domain II (MutS_II) (126-239)

• MutS domain III (MutS_III) (256-546)

• MutS domain V (MutS_V) (599-785)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	73.995	100	0.74
mutS	Pseudomonas stutzeri strain ATCC 17587	37.413	100	0.379