Detailed information NTG0021581

Bioinformatically predicted

Overview

• Name: pilA
• Type: Machinery gene
• Locus tag: NMB_RS00245
• Genome accession: NC_003112
• Coordinates: 43186..44451 (+)
• Length: 421 a.a.
• NCBI ID: WP_002243928.1
• Uniprot ID: P57011
• Organism: Neisseria meningitidis MC58
• Function: assembly of type IV pilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 38186..49451

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NMB_RS00225 (NMB0041)	-	38916..39917 (+)	1002	WP_002243927.1	thiamine ABC transporter substrate-binding protein	-
NMB_RS00230 (NMB0042)	-	40011..40859 (+)	849	WP_002215243.1	mechanosensitive ion channel family protein	-
NMB_RS00235 (NMB0043)	-	40885..41370 (+)	486	WP_002215245.1	CinA family protein	-
NMB_RS00240 (NMB0044)	msrAB	41472..43040 (-)	1569	WP_010980745.1	bifunctional peptide-methionine (S)-S-oxide reductase MsrA/peptide-methionine (R)-S-oxide reductase MsrB	-
NMB_RS00245 (NMB0045)	pilA	43186..44451 (+)	1266	WP_002243928.1	signal recognition particle-docking protein FtsY	Machinery gene
NMB_RS00250 (NMB0047)	-	45079..45363 (+)	285	WP_002216166.1	GIY-YIG nuclease family protein	-
NMB_RS11990	pilC	48123..48260 (+)	138	WP_164734201.1	hypothetical protein	Machinery gene

Sequence

Protein

• Length: 421 a.a.
• Molecular weight: 45143.47 Da
• Isoelectric Point: 4.5557

>NTDB_id=21581 NMB_RS00245 WP_002243928.1 43186..44451(+) (pilA) [Neisseria meningitidis MC58]
MFSFFRRKKKQETPALEEAQIQETAAKAESELAQIVENIKEDAESLAESVKGQVESAVETVSGAVEQVKETVAEMLSEAE
EAAEKAAEQVEAAKEAVAETVGEAVGQVQEAVATTEEHKLGWAARLKQGLTKSRDKMAKSLAGVFGGGQIDEDLYEELET
VLITSDMGMEATEYLMKDVRDRVSLKGLKDGNELRGALKEALYDLIKPLEKPLVLPETKEPFVIMLAGINGAGKTTSIGK
LAKYFQAQGKSVLLAAGDTFRAAAREQLQAWGERNNVTVISQTTGDSAAVCFDAVQAAKARGIDIVLADTAGRLPTQLHL
MEEIKKVKRVLQKAMPDAPHEIIVVLDANIGQNAVNQVKAFDDALGLTGLIVTKLDGTAKGGILAALASDRPVPVRYIGV
GEGIDDLRPFDARAFVDALLD

Nucleotide

• Length: 1266 bp

>NTDB_id=21581 NMB_RS00245 WP_002243928.1 43186..44451(+) (pilA) [Neisseria meningitidis MC58]
ATGTTCAGCTTCTTCCGTCGCAAGAAAAAACAGGAAACGCCGGCTCTCGAGGAGGCTCAAATTCAGGAAACCGCAGCAAA
AGCAGAATCTGAACTTGCTCAAATAGTTGAAAATATTAAAGAAGATGCTGAATCTTTAGCAGAAAGCGTCAAAGGGCAGG
TCGAATCTGCCGTTGAAACCGTCAGCGGTGCGGTTGAACAGGTAAAGGAAACCGTTGCCGAGATGCTGTCTGAAGCAGAG
GAAGCGGCGGAAAAAGCAGCGGAACAAGTCGAAGCGGCAAAAGAAGCCGTTGCCGAAACCGTCGGCGAGGCTGTCGGGCA
AGTTCAAGAAGCCGTTGCGACAACTGAAGAACACAAGCTCGGTTGGGCGGCGCGTTTGAAACAAGGCCTGACCAAATCGC
GCGACAAAATGGCGAAATCGCTGGCGGGCGTGTTCGGCGGCGGACAAATCGACGAAGATTTATACGAAGAGCTGGAAACC
GTGCTGATTACCAGCGATATGGGCATGGAAGCCACCGAATACCTGATGAAAGACGTGCGCGACCGCGTCAGCCTCAAAGG
GCTGAAAGACGGCAACGAATTGCGCGGCGCGTTGAAAGAAGCCTTGTACGACCTGATTAAGCCTCTGGAGAAACCTTTGG
TTTTGCCCGAAACCAAAGAGCCGTTTGTCATCATGCTTGCCGGCATCAACGGCGCGGGCAAAACCACGTCTATCGGTAAA
CTCGCCAAATATTTCCAAGCGCAGGGCAAATCCGTATTGCTGGCGGCAGGCGATACTTTCCGTGCCGCCGCGCGTGAGCA
GCTTCAAGCTTGGGGCGAGCGCAACAACGTAACCGTGATTTCGCAAACCACGGGCGATTCCGCCGCCGTGTGCTTCGATG
CCGTCCAAGCCGCCAAAGCGCGCGGCATCGACATTGTGCTGGCCGACACCGCCGGCCGCCTGCCCACGCAGCTTCATTTG
ATGGAAGAAATCAAAAAAGTGAAACGCGTGCTGCAAAAAGCCATGCCCGACGCGCCGCACGAAATCATCGTCGTGCTTGA
TGCCAATATCGGGCAAAACGCCGTCAACCAAGTCAAAGCCTTTGACGACGCATTGGGGCTGACCGGTTTAATCGTTACCA
AACTCGACGGCACGGCAAAAGGCGGCATCCTCGCCGCGCTTGCCTCCGACCGCCCCGTTCCCGTCCGCTATATCGGCGTG
GGCGAAGGCATAGACGACCTGCGCCCGTTTGACGCGCGCGCGTTTGTGGACGCACTGCTGGATTGA

Domains

Predicted by InterproScan.

• SRP54-type protein, GTPase domain (SRP54) (221-420)

• SRP54-type protein, helical bundle domain (SRP54_N) (136-202)

3D structure

• AlphaFold DB: P57011

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilA	Neisseria gonorrhoeae MS11	94.774	100	0.948